ID U3JNE8_FICAL Unreviewed; 454 AA.
AC U3JNE8;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 2.
DT 24-JAN-2024, entry version 57.
DE SubName: Full=Regulator of G protein signaling 11 {ECO:0000313|Ensembl:ENSFALP00000004302.2};
GN Name=RGS11 {ECO:0000313|Ensembl:ENSFALP00000004302.2};
OS Ficedula albicollis (Collared flycatcher) (Muscicapa albicollis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Muscicapidae; Ficedula.
OX NCBI_TaxID=59894 {ECO:0000313|Ensembl:ENSFALP00000004302.2, ECO:0000313|Proteomes:UP000016665};
RN [1] {ECO:0000313|Ensembl:ENSFALP00000004302.2, ECO:0000313|Proteomes:UP000016665}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23103876; DOI=10.1038/nature11584;
RA Ellegren H., Smeds L., Burri R., Olason P.I., Backstrom N., Kawakami T.,
RA Kunstner A., Makinen H., Nadachowska-Brzyska K., Qvarnstrom A., Uebbing S.,
RA Wolf J.B.;
RT "The genomic landscape of species divergence in Ficedula flycatchers.";
RL Nature 491:756-760(2012).
RN [2] {ECO:0000313|Ensembl:ENSFALP00000004302.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_016157311.1; XM_016301825.1.
DR AlphaFoldDB; U3JNE8; -.
DR STRING; 59894.ENSFALP00000004302; -.
DR Ensembl; ENSFALT00000004323.2; ENSFALP00000004302.2; ENSFALG00000004130.2.
DR GeneID; 101812847; -.
DR CTD; 8786; -.
DR eggNOG; KOG3589; Eukaryota.
DR GeneTree; ENSGT00940000160198; -.
DR HOGENOM; CLU_025092_0_0_1; -.
DR OrthoDB; 22856at2759; -.
DR Proteomes; UP000016665; Chromosome 14.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
DR GO; GO:0008277; P:regulation of G protein-coupled receptor signaling pathway; IEA:InterPro.
DR CDD; cd04450; DEP_RGS7-like; 1.
DR CDD; cd00068; GGL; 1.
DR CDD; cd08740; RGS_RGS11; 1.
DR Gene3D; 1.10.1240.60; -; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR Gene3D; 4.10.260.10; Transducin (heterotrimeric G protein), gamma chain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000591; DEP_dom.
DR InterPro; IPR015898; G-protein_gamma-like_dom.
DR InterPro; IPR036284; GGL_sf.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR047016; RGS6/7/9/11.
DR InterPro; IPR047017; RGS6/7/9/11_DHEX_sf.
DR InterPro; IPR040759; RGS_DHEX.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR45746; LP21163P; 1.
DR PANTHER; PTHR45746:SF3; REGULATOR OF G-PROTEIN SIGNALING 11; 1.
DR Pfam; PF00610; DEP; 1.
DR Pfam; PF00631; G-gamma; 1.
DR Pfam; PF00615; RGS; 1.
DR Pfam; PF18148; RGS_DHEX; 1.
DR PRINTS; PR01301; RGSPROTEIN.
DR SMART; SM00049; DEP; 1.
DR SMART; SM01224; G_gamma; 1.
DR SMART; SM00224; GGL; 1.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR SUPFAM; SSF48670; Transducin (heterotrimeric G protein), gamma chain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50186; DEP; 1.
DR PROSITE; PS50132; RGS; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000016665};
KW Signal transduction inhibitor {ECO:0000256|ARBA:ARBA00022700}.
FT DOMAIN 17..92
FT /note="DEP"
FT /evidence="ECO:0000259|PROSITE:PS50186"
FT DOMAIN 286..401
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
FT REGION 418..454
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 454 AA; 53115 MW; 47F584B52C7D2F0E CRC64;
MPCLSKMERM IVSMQDPDMG IKMRNQRLLI TVIPHAMTGN DIVEWLIQKY GISEEESLHL
GNLIVKHGYI YPLKDPRSLV LRADESPYRF QTPYFWTSTK WPATELDYAI YLAKKNIRKQ
GDLIEHEKDN YNLLHKRINH TWDFVVMQAR EQLRAAKQRR KGDRIVIDCQ EQAYWLVNRP
PPGAPNVLEQ GPERRNCHTT RVQLNMDYYK REIEYCRKAM ARTRVKSSIC LEGYIKFNEQ
YVPHDPIMSG CLPSNPWITD DTTYWAMNAP TVTTPTKLRV ERWGFNFSEL INDPLGRAQL
LEFLKKEFSA ENLSFWEACE ELRYGEQSRI AEIVDSIYQQ FLAPGATRWV NIDSKTMERT
LEGIKTPHRY VMDDAQMHIY MLMKKDSYPR FLKSDLYKNL LAEAVIPPET KKRVFPFMRK
QRHSSPSPAL LLPAGDAEEK SRSPSTAPVP EEES
//
