ID U3JW70_FICAL Unreviewed; 802 AA.
AC U3JW70;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 2.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=Signal recognition particle subunit SRP72 {ECO:0000256|ARBA:ARBA00018350};
GN Name=SRP72 {ECO:0000313|Ensembl:ENSFALP00000007024.2};
OS Ficedula albicollis (Collared flycatcher) (Muscicapa albicollis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Muscicapidae; Ficedula.
OX NCBI_TaxID=59894 {ECO:0000313|Ensembl:ENSFALP00000007024.2, ECO:0000313|Proteomes:UP000016665};
RN [1] {ECO:0000313|Ensembl:ENSFALP00000007024.2, ECO:0000313|Proteomes:UP000016665}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23103876; DOI=10.1038/nature11584;
RA Ellegren H., Smeds L., Burri R., Olason P.I., Backstrom N., Kawakami T.,
RA Kunstner A., Makinen H., Nadachowska-Brzyska K., Qvarnstrom A., Uebbing S.,
RA Wolf J.B.;
RT "The genomic landscape of species divergence in Ficedula flycatchers.";
RL Nature 491:756-760(2012).
RN [2] {ECO:0000313|Ensembl:ENSFALP00000007024.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00004240}.
CC -!- SIMILARITY: Belongs to the SRP72 family.
CC {ECO:0000256|ARBA:ARBA00007676}.
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DR AlphaFoldDB; U3JW70; -.
DR STRING; 59894.ENSFALP00000007024; -.
DR Ensembl; ENSFALT00000007055.2; ENSFALP00000007024.2; ENSFALG00000006713.2.
DR eggNOG; KOG2376; Eukaryota.
DR GeneTree; ENSGT00390000013264; -.
DR HOGENOM; CLU_013808_1_0_1; -.
DR Proteomes; UP000016665; Chromosome 4.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR GO; GO:0005786; C:signal recognition particle, endoplasmic reticulum targeting; IEA:UniProtKB-KW.
DR GO; GO:0008312; F:7S RNA binding; IEA:Ensembl.
DR GO; GO:0043022; F:ribosome binding; IEA:Ensembl.
DR GO; GO:0005047; F:signal recognition particle binding; IEA:Ensembl.
DR GO; GO:0030911; F:TPR domain binding; IEA:Ensembl.
DR GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; IEA:InterPro.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 4.
DR InterPro; IPR013699; Signal_recog_part_SRP72_RNA-bd.
DR InterPro; IPR026270; SRP72.
DR InterPro; IPR031545; SRP72_TPR-like.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR14094; SIGNAL RECOGNITION PARTICLE 72; 1.
DR PANTHER; PTHR14094:SF9; SIGNAL RECOGNITION PARTICLE SUBUNIT SRP72; 1.
DR Pfam; PF08492; SRP72; 1.
DR Pfam; PF17004; SRP_TPR_like; 1.
DR Pfam; PF13181; TPR_8; 1.
DR SMART; SM00028; TPR; 3.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Reference proteome {ECO:0000313|Proteomes:UP000016665};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274};
KW Signal recognition particle {ECO:0000256|ARBA:ARBA00023135};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT REPEAT 358..391
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 664..720
FT /note="Signal recognition particle SRP72 subunit RNA-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF08492"
FT REGION 75..125
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 663..802
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 226..281
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 696..717
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 731..774
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 788..802
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 802 AA; 87975 MW; 49F16C2CE9A6F2ED CRC64;
MCPWLCLMPP RTGFGLLAAR HNDSHSIAIH QDPQLPFHST ALQPLVPQSM HTARVAQVQN
RQWPRLHLIE QKLDSETIKA HGPSGGSGRA GGGAGKGGAA GRVRAPAGGG APLGSSASGA
APLPRRVSRP GAKMAAAAGA AAVAGLWSEV NRCGQNGDFA RALKSVNKIL QINKDDVTAL
HCKVVCLIQN GNFKEALGVI NTHTKVLTSD VIAFEKAYCE YRLNRIESAL KTIQSASQQT
DKLKELYGQV LYRLERYDDC LAAYRDLIRN SQDEYEEERK TNLSAVVAAQ STWEKVVPED
LGLREATYEL CYNSACALIG QGKLNEAMKK LQKAEELCRQ SLSEDSDVTE EDIEAELAII
HGQMAYIMQL QGRTEDALQL YNQIIKLKPT DVGLLAVIAN NIITINKDQN VFDSKKKVKL
TNAEGVEHKL SKKQLQAIEF NKALLAMYTN QADQCRKLSA SLQSQSPEHL LPVLIQAAQL
CREKQHAKAV VLLQDFAEQH PANAAEIKLT MAQLKIAQGS VTKACMILRS IEELQHKPGM
VSALVTMYSH EEDIDSAIEV FTQAIQWYQQ HQPKSPVHLS LIREAANFKL KHGRKKEAIS
DLEELWKQNP KDVHTLAQLI SAYSLVDPEK AKVLSKHLPS SDTMSLKVDV DALENSHGAT
YVRKKAGKLT GDNQQKEQGQ GEVKKKKKKK KGKLPKNYDP KVTPDPERWL PMRERSYYRG
RKKGKKKDQV GKGTQGSTTT GSSELDASRT ASSPPTSPRP GSGAAVSATS NVIPPRHQKP
AGAPATKKKQ QQKKKKGAKG GW
//
