ID U3K1E6_FICAL Unreviewed; 1561 AA.
AC U3K1E6;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=PPARG related coactivator 1 {ECO:0000313|Ensembl:ENSFALP00000008850.1};
GN Name=PPRC1 {ECO:0000313|Ensembl:ENSFALP00000008850.1};
OS Ficedula albicollis (Collared flycatcher) (Muscicapa albicollis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Muscicapidae; Ficedula.
OX NCBI_TaxID=59894 {ECO:0000313|Ensembl:ENSFALP00000008850.1, ECO:0000313|Proteomes:UP000016665};
RN [1] {ECO:0000313|Ensembl:ENSFALP00000008850.1, ECO:0000313|Proteomes:UP000016665}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23103876; DOI=10.1038/nature11584;
RA Ellegren H., Smeds L., Burri R., Olason P.I., Backstrom N., Kawakami T.,
RA Kunstner A., Makinen H., Nadachowska-Brzyska K., Qvarnstrom A., Uebbing S.,
RA Wolf J.B.;
RT "The genomic landscape of species divergence in Ficedula flycatchers.";
RL Nature 491:756-760(2012).
RN [2] {ECO:0000313|Ensembl:ENSFALP00000008850.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_016154957.1; XM_016299471.1.
DR Ensembl; ENSFALT00000008888.2; ENSFALP00000008850.1; ENSFALG00000008489.2.
DR GeneID; 101809734; -.
DR CTD; 23082; -.
DR eggNOG; ENOG502QQME; Eukaryota.
DR GeneTree; ENSGT00950000183137; -.
DR HOGENOM; CLU_001907_0_0_1; -.
DR OMA; YWPGIPM; -.
DR OrthoDB; 3134278at2759; -.
DR Proteomes; UP000016665; Chromosome 6.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003712; F:transcription coregulator activity; IEA:InterPro.
DR CDD; cd12624; RRM_PRC; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR034605; PGC-1.
DR InterPro; IPR034834; PRC_RRM.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR15528; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1 PGC-1 -RELATED; 1.
DR PANTHER; PTHR15528:SF5; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA COACTIVATOR-RELATED PROTEIN 1; 1.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000016665};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 1440..1516
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 280..419
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 431..658
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 810..1012
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1038..1135
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1172..1234
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1252..1417
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 324..349
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 352..384
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 394..419
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 431..445
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 510..534
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 557..580
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 898..912
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 937..954
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1053..1073
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1252..1266
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1273..1287
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1300..1350
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1364..1404
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1561 AA; 167179 MW; 6B8AF4D48EF59661 CRC64;
MQNYLDSSVI SIIEDLSLSE QSRACLDAQN ELSLLTAITE ILDSTDDETL SPFDTIMDAE
LLTSPREREN PSFQKFLTLS CPLLECESPA LEQPKALRPL SSSSSSSVSV VGKIDTDMAW
DRAAHGLEDP VLPKKQVCST SRVERKVGWH RAREQPLPQR SDGEEEEEEA ALSLELHSNM
EAVDFCVSEA GAALEENEDP CIINTSDVSL SELVKSMHPY CLPTFTVCLD PDTEPVAKEL
LSSPVLLEIV PGEGESVEIP VVLQPLTPSS PDLEPQLLGV EESTRESVQE DQEELPGTPT
QENGVEDEEK GKLPGKEPSC SIPEATSPLE TTAPGASGPN SSSWHSTEAP ASGKRECSEK
GRGRERARKS RKKKAEEDQS KQARPGRDFV VQRLRSTGSG QSHVQPAISR QRAECPSVQV
SDFLAQQLER ARKEGKMELH AEQALQSRGK PRSTTGAFLP KKGKQELQKE PAPETVSVAL
EKKTQVPLEK TAPSVEGQPA AACPSLTDQA EGQGDVQPSA EQSSGVSQAA SQLPEQGVGL
EPAQSLPASE GLPKEAKPKA LSLREYRIRM LHRKPSMDGS QEGKKQVAGK WPSVPEPPTE
LAEIPCLVSP MRSATEADSA QKGPDKPTSP AAVPPPASKA PTALTSAPAA ATAPPPPSTP
MPFVAPNVPP VAGVAPTGMP PASAGAYALY PPVPSWPCFS PQPMGCHGLP PPPSASSSSS
FHMVPGLPPP AMAWPPPPVP PLPPFGPGGP YAPVGWAPPS YWPGIPMPPP VPSLAYRDPG
AGVQAATAFP AGSQPGTALL HGQLPATPML SCPEPPAFPT QSPAAPTSEM GAAGGPARPV
TGRVSDPRRQ SRLAGESSLP KAPLAPAPAQ PLPAPSAATA QPSRVPPAVP VPQAVPTQPL
EEPQTATPTQ LLKTPPAAIC CPAEVSPAPV EESPGTHTTE KAVEPGKEAV EEALLEPKTA
AGQELPGQKA TSQAVEPPPK AGRESSLPTK APAVRPWRHQ PLLSPAQPSD SNKDIVQAFI
SEIGIEATDL SSLLEQFEKS EAKKEETSVQ PPEEKQLVGS SGPETQQDVP SQQDRKPPDG
LQASELANVA GLTPPATPPH QLWKPLPAVS LLAKTKSPGS MPQEGPQKTT KLMKAKPLPP
NKIQVKSMVP AAPSTAPTHV CSGDHDYCIL GTPRPESSNI PGTQPPAKGG SRWNVKHHRD
ITIKPISSLT KRTLDQPEPT PPAPDTTTGH SQEPLGMACL APLDYRTTIP NKATTGCSSP
PTSVLLSPAA SPCRDQEVQT PSAQPSHAAA KRSLRCYRRP QDSPSPSSDS WRAGRSRASR
SFSSSSDGAS ESSSSSSSSS SRSQSRSLSP PPKRWRRYRS RCSHSSSSRS SCGSCGRSRE
RSSSSSSTSS YSSRSTSRSQ SRSPSPRRRS NRWRRYSYDA QDHYQRQRIL QKERAIEERR
VVFIGKIPSR MTRSELRHRF SVFGDIEECT LHFRSEGDNY GFVTYRYAEE AFAAIESGHK
LRRPDEQPFD LCFGGRRQFC RRNYADLDSN REDFDPAPVK SKFDSLDFDT LLRQAQRSLR
R
//
