ID   U3K230_FICAL            Unreviewed;       231 AA.
AC   U3K230;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   29-SEP-2021, sequence version 2.
DT   24-JAN-2024, entry version 43.
DE   SubName: Full=Otolin 1 {ECO:0000313|Ensembl:ENSFALP00000009084.2};
GN   Name=OTOL1 {ECO:0000313|Ensembl:ENSFALP00000009084.2};
OS   Ficedula albicollis (Collared flycatcher) (Muscicapa albicollis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Passeriformes; Muscicapidae; Ficedula.
OX   NCBI_TaxID=59894 {ECO:0000313|Ensembl:ENSFALP00000009084.2, ECO:0000313|Proteomes:UP000016665};
RN   [1] {ECO:0000313|Ensembl:ENSFALP00000009084.2, ECO:0000313|Proteomes:UP000016665}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23103876; DOI=10.1038/nature11584;
RA   Ellegren H., Smeds L., Burri R., Olason P.I., Backstrom N., Kawakami T.,
RA   Kunstner A., Makinen H., Nadachowska-Brzyska K., Qvarnstrom A., Uebbing S.,
RA   Wolf J.B.;
RT   "The genomic landscape of species divergence in Ficedula flycatchers.";
RL   Nature 491:756-760(2012).
RN   [2] {ECO:0000313|Ensembl:ENSFALP00000009084.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; U3K230; -.
DR   STRING; 59894.ENSFALP00000009084; -.
DR   Ensembl; ENSFALT00000009123.2; ENSFALP00000009084.2; ENSFALG00000008708.2.
DR   eggNOG; ENOG502QRPC; Eukaryota.
DR   GeneTree; ENSGT00940000155435; -.
DR   HOGENOM; CLU_001074_0_0_1; -.
DR   Proteomes; UP000016665; Chromosome 9.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:Ensembl.
DR   GO; GO:0045299; P:otolith mineralization; IEA:Ensembl.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   Gene3D; 2.60.120.40; -; 1.
DR   InterPro; IPR001073; C1q_dom.
DR   InterPro; IPR008160; Collagen.
DR   InterPro; IPR008983; Tumour_necrosis_fac-like_dom.
DR   PANTHER; PTHR15427:SF44; C1Q DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR15427; EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER; 1.
DR   Pfam; PF00386; C1q; 1.
DR   Pfam; PF01391; Collagen; 1.
DR   PRINTS; PR00007; COMPLEMNTC1Q.
DR   SMART; SM00110; C1Q; 1.
DR   SUPFAM; SSF49842; TNF-like; 1.
DR   PROSITE; PS50871; C1Q; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000016665};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           22..231
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5032717332"
FT   DOMAIN          93..228
FT                   /note="C1q"
FT                   /evidence="ECO:0000259|PROSITE:PS50871"
FT   REGION          23..108
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        46..61
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   231 AA;  24614 MW;  A32B5CE199F02CE6 CRC64;
     MRNSDDPVLL FLILFLPSGE AGAKGNKGSY GFPGLKGQKG AKGDTCDNGT KGDKGDRGDP
     GEPGVGGEQG DKGEKGDTGD KGYCGEPGGR GAPRAPRSAF SAGLARPFPP PNAPIRFERV
     WYDERRDYDP NTGKFNCSVA GAYVFSYHVT VRGRPARLSL VAGGRRVAKA RDTLYGQDVD
     QASFLTILKL RVGDQVWLGA AKDWNGLYAG AEDDSVFTGF LLYPDGFEVL L
//