ID U3K9Q4_FICAL Unreviewed; 621 AA.
AC U3K9Q4;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 2.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=Solute carrier family 23 member 1 {ECO:0008006|Google:ProtNLM};
GN Name=LOC101821303 {ECO:0000313|Ensembl:ENSFALP00000011758.2};
OS Ficedula albicollis (Collared flycatcher) (Muscicapa albicollis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Muscicapidae; Ficedula.
OX NCBI_TaxID=59894 {ECO:0000313|Ensembl:ENSFALP00000011758.2, ECO:0000313|Proteomes:UP000016665};
RN [1] {ECO:0000313|Ensembl:ENSFALP00000011758.2, ECO:0000313|Proteomes:UP000016665}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23103876; DOI=10.1038/nature11584;
RA Ellegren H., Smeds L., Burri R., Olason P.I., Backstrom N., Kawakami T.,
RA Kunstner A., Makinen H., Nadachowska-Brzyska K., Qvarnstrom A., Uebbing S.,
RA Wolf J.B.;
RT "The genomic landscape of species divergence in Ficedula flycatchers.";
RL Nature 491:756-760(2012).
RN [2] {ECO:0000313|Ensembl:ENSFALP00000011758.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR AlphaFoldDB; U3K9Q4; -.
DR STRING; 59894.ENSFALP00000011758; -.
DR Ensembl; ENSFALT00000011806.2; ENSFALP00000011758.2; ENSFALG00000011238.2.
DR eggNOG; KOG1292; Eukaryota.
DR GeneTree; ENSGT00950000182953; -.
DR HOGENOM; CLU_017959_5_4_1; -.
DR OrthoDB; 911690at2759; -.
DR Proteomes; UP000016665; Chromosome 1A.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0071702; P:organic substance transport; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR InterPro; IPR006042; Xan_ur_permease.
DR PANTHER; PTHR11119:SF22; SOLUTE CARRIER FAMILY 23 MEMBER 4; 1.
DR PANTHER; PTHR11119; XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
DR PROSITE; PS01116; XANTH_URACIL_PERMASE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000016665};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 55..81
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 93..115
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 176..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 224..244
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 265..288
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 327..345
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 414..433
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 439..461
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 473..491
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 507..527
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..38
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 600..621
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 621 AA; 66511 MW; D7A1749B9015B7D5 CRC64;
ETETPSNVSS GLDTPGEHGS HCHSSPAHAA WGPEEGGGTG HRGTKLGYIV TDVPPWYLCI
LLGIQHFLTA MGGLVAIPLI LSEGLCLQHD LLTQSHLIST IFFVSGICTL LQVLFGVRLP
IIQGGTFTFL TPTLAMLSLP SWKCPAWTQN ATLVNASSPE FIQVWQTRMR EVQGTIIVAS
CFQIFVGFSG LIGFLMRFIG PLTIAPTITL VALPLFESAG DMAGQHWGVA FMTIFFIVLF
SQYLKDVAVP LPSYQRAEKC HFSPIYLFQI FPVLLGLSLS WLLCYVLTVA SVLPAAPAAY
GHLARTDTRG AVLAQAPWFR LPYPGQWGRP TVSLAGIFGM LAGVISSMLE SVGDYYACAR
LCGAPSPPQH AISRGIGVEG IGCLLAGAWG TGSGTTSYSE NVGALGITKV GSRVVIIAGA
CAMLLSGIFG KVGAMLASIP IPVIGGMFLV MFGVITAVGI SNLQYTDMNS SRNIFIFGFS
LFAGLTIPNW ANKNSTLLET GIMQLDQVIL VLLTTGMFVG GLLGFILDNT IPGTQEERGL
LAWKQSHEGG MESSQLVSKV YDLPFGIGTK YCNVSWFHYL PACPKRLPCD NRMNELKAAG
QKNSLKASLE RNSETGDDTR I
//
