ID U3KAJ3_FICAL Unreviewed; 807 AA.
AC U3KAJ3;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 2.
DT 24-JAN-2024, entry version 47.
DE SubName: Full=Plakophilin 3 {ECO:0000313|Ensembl:ENSFALP00000012047.2};
GN Name=PKP3 {ECO:0000313|Ensembl:ENSFALP00000012047.2};
OS Ficedula albicollis (Collared flycatcher) (Muscicapa albicollis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Muscicapidae; Ficedula.
OX NCBI_TaxID=59894 {ECO:0000313|Ensembl:ENSFALP00000012047.2, ECO:0000313|Proteomes:UP000016665};
RN [1] {ECO:0000313|Ensembl:ENSFALP00000012047.2, ECO:0000313|Proteomes:UP000016665}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23103876; DOI=10.1038/nature11584;
RA Ellegren H., Smeds L., Burri R., Olason P.I., Backstrom N., Kawakami T.,
RA Kunstner A., Makinen H., Nadachowska-Brzyska K., Qvarnstrom A., Uebbing S.,
RA Wolf J.B.;
RT "The genomic landscape of species divergence in Ficedula flycatchers.";
RL Nature 491:756-760(2012).
RN [2] {ECO:0000313|Ensembl:ENSFALP00000012047.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the beta-catenin family.
CC {ECO:0000256|ARBA:ARBA00005462}.
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DR AlphaFoldDB; U3KAJ3; -.
DR STRING; 59894.ENSFALP00000012047; -.
DR Ensembl; ENSFALT00000012096.2; ENSFALP00000012047.2; ENSFALG00000011536.2.
DR eggNOG; KOG1048; Eukaryota.
DR GeneTree; ENSGT00940000159515; -.
DR HOGENOM; CLU_009111_2_0_1; -.
DR Proteomes; UP000016665; Chromosome 5.
DR GO; GO:0001533; C:cornified envelope; IEA:Ensembl.
DR GO; GO:0030057; C:desmosome; IEA:Ensembl.
DR GO; GO:1990124; C:messenger ribonucleoprotein complex; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0045294; F:alpha-catenin binding; IEA:Ensembl.
DR GO; GO:0050839; F:cell adhesion molecule binding; IEA:Ensembl.
DR GO; GO:0019899; F:enzyme binding; IEA:Ensembl.
DR GO; GO:0098609; P:cell-cell adhesion; IEA:InterPro.
DR GO; GO:0002159; P:desmosome assembly; IEA:Ensembl.
DR GO; GO:1902373; P:negative regulation of mRNA catabolic process; IEA:Ensembl.
DR GO; GO:0072659; P:protein localization to plasma membrane; IEA:Ensembl.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR028435; Plakophilin/d_Catenin.
DR PANTHER; PTHR10372:SF1; PLAKOPHILIN-3; 1.
DR PANTHER; PTHR10372; PLAKOPHILLIN-RELATED; 1.
DR Pfam; PF00514; Arm; 2.
DR SMART; SM00185; ARM; 3.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50176; ARM_REPEAT; 2.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Reference proteome {ECO:0000313|Proteomes:UP000016665}.
FT REPEAT 372..415
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 414..445
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REGION 60..155
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 257..300
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 257..272
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 273..291
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 807 AA; 89225 MW; F9BC0230CB47EBE8 CRC64;
MQETNAFLLS ALQPEAGVCS LALPSDRQLD ERGREAAEAQ RLRSARVQEQ VRIRMMLRGQ
APARPDDLAD GTRGGRNPRA PLGTRGGMGG GSPPAGTGLW AHPGCGLGGA PHPERVPRPP
PSIASCPRRR GTRQGGEATS APRGQRAGEG GLLPPLCPPQ PCLRCRGSRS RSPWDELGRS
WLGRSLPALP VLTLPPLWLS RRWSVQLDPA LLLQLPLPEQ WRGPQSLGTY RGSVPCPRPR
LCRGDRTIRA PAMRTLQRFQ SNNRSRLSTG SFGTVPPPPP PPPPPPPRSR APSVRSLAES
GHHLAEPRAM EMYNGHSTLL GHHAGGFDDI DLPSAVKYLI ASDPNLQVLG AAYLQHKCYS
DSSAKKQARS LQAMPKLVKL FNSPNQEVQR HATGAMRNLI YDNAENKLAL VEENGIYELM
RTLREPDDEL RKNVTGILWN LSSSDNLKDR LARDTLEQLT DLVLVPLSGL GGSGVIQQNP
SEAEIFYNST GFLRNLSSAS QQTRQKMREC HGLVDSMIHY VNSSLEVGKS EDKSVENAVC
VLRNLSYRLY DEMPPSSLQR LEGHRRNAGG TVTGELVGCF SPQSKKAREH YLNADIVTFT
EVSKDPKGME WLWNPQIVGI YNRLLQRCEL NKHTTEAASG ALQNITAGDR RWAGVLSRLA
LEQERILNPV LDRVRTADHH QLRSLTGLIR NLSRHARNKD EMSTKVVSHL IEKLPGSVGD
KAPPADVIVN IIAVLNNLVV ESPMAARDIV YFDGLRKLFF IKKRRDSSDN EKSSRAAASL
LGNMWQYTKL HRDFKMKGYR KEDFLSL
//
