ID   U3KGW3_FICAL            Unreviewed;      1180 AA.
AC   U3KGW3;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   27-MAR-2024, entry version 59.
DE   RecName: Full=Intraflagellar transport protein 122 homolog {ECO:0000256|ARBA:ARBA00019442};
GN   Name=IFT122 {ECO:0000313|Ensembl:ENSFALP00000014267.1};
OS   Ficedula albicollis (Collared flycatcher) (Muscicapa albicollis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Passeriformes; Muscicapidae; Ficedula.
OX   NCBI_TaxID=59894 {ECO:0000313|Ensembl:ENSFALP00000014267.1, ECO:0000313|Proteomes:UP000016665};
RN   [1] {ECO:0000313|Ensembl:ENSFALP00000014267.1, ECO:0000313|Proteomes:UP000016665}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23103876; DOI=10.1038/nature11584;
RA   Ellegren H., Smeds L., Burri R., Olason P.I., Backstrom N., Kawakami T.,
RA   Kunstner A., Makinen H., Nadachowska-Brzyska K., Qvarnstrom A., Uebbing S.,
RA   Wolf J.B.;
RT   "The genomic landscape of species divergence in Ficedula flycatchers.";
RL   Nature 491:756-760(2012).
RN   [2] {ECO:0000313|Ensembl:ENSFALP00000014267.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   RefSeq; XP_016156930.1; XM_016301444.1.
DR   AlphaFoldDB; U3KGW3; -.
DR   STRING; 59894.ENSFALP00000014267; -.
DR   Ensembl; ENSFALT00000014326.2; ENSFALP00000014267.1; ENSFALG00000013670.2.
DR   GeneID; 101819636; -.
DR   CTD; 55764; -.
DR   eggNOG; KOG1538; Eukaryota.
DR   GeneTree; ENSGT00390000001016; -.
DR   HOGENOM; CLU_008896_0_0_1; -.
DR   OMA; GDSFDTW; -.
DR   OrthoDB; 5484092at2759; -.
DR   Proteomes; UP000016665; Chromosome 12.
DR   GO; GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
DR   GO; GO:0060271; P:cilium assembly; IEA:InterPro.
DR   Gene3D; 1.25.40.470; -; 2.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR039857; Ift122/121.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR12764:SF4; INTRAFLAGELLAR TRANSPORT PROTEIN 122 HOMOLOG; 1.
DR   PANTHER; PTHR12764; WD REPEAT DOMAIN-RELATED; 1.
DR   Pfam; PF00400; WD40; 3.
DR   SMART; SM00320; WD40; 8.
DR   SUPFAM; SSF50978; WD40 repeat-like; 2.
DR   PROSITE; PS50082; WD_REPEATS_2; 1.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000016665};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW   ProRule:PRU00221}.
FT   REPEAT          49..80
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
SQ   SEQUENCE   1180 AA;  134821 MW;  6DCA7DEAE0133CFE CRC64;
     MRAALTWRDR AEQCIYDLAF KPDGTQLIIA AGNRLLVYDT SDGTLIQPLK GHKDTVYCVA
     YAKDGKRFAS GSADKSVIIW TSKLEGILKY THNDSIQCVS YNPLTHQLAS CSSGDFGLWS
     PEQKSVSKHK TSCKITCCSW TNDGQYLALG MFNGIVSIRN KNGDEKVKIE RPGGSSSPIW
     SICWNPSRDE RNDILAVADW GQKLSFYHLS GKQIGKDRVL NFDPCCISYF TKGEYLLLGG
     SDRQVSLFTR DGVRLGTVGE QSSWVWTCKV KPDSNYVAVG CQDGTISFYQ LIFSTVHGLY
     KDRYAYRDSM TDVIVQHLIT EQKVRIKGRE LVKKIAIYKN RLAIQMPEKI LIYELYSDDS
     ADMYYRVKEK IMKKFECNLL VVCSDHIILC QEKRLQCLSF SGVKEREWLM ESLIRYIKVI
     GGPPGREGLL VGLKNGQILK IFVDNGLAMV LLKQATAVRC LDMSASRRKL AVVDENDTCL
     VYDIHTKELL FQEPNANSVA WNTQCEDMLC FSGGGYLNIK ASNFPVHQQK LQGFVVGYNG
     SKIFCLHVFS MSAVEVPQSA PMYQYLERKM FKEAYQIACL GVTDADWREL AMEALEGLEF
     ETAKKAFTRV RDLRYLELIS SIEDRKKQGE NNSDLFLADV FAYQGKFQEA AKLYKRSGHE
     PLALEMYSEL RMFEHAKEFL GSGDPKDTKM LIKKQADWAK DINEPKAAVE MYLSAGEHMK
     AIEISGDHGW VDLLIEIARK LDRAEREPLA KCAFYFKQLD NPGYAAETYM KVGDLRALVQ
     LHVETRRWEE AFALCEKHPE FKDEVYVPYA QWLAESDRFE EAQKAFHRAG RQREAVRVLE
     QLTHNAVLES RFSDAARYYW MLSMQCLDIA RENAGQQTEM LQKFHHFQHL AEVYHVYHFI
     QRYTEEPFSF HLPETLFNIS RFLLHSLTKE TPLGISKVNT LLALAKQSKA LGAYKLARHA
     YDKLQGLQIP DRFQKSVELG SLTIRSKPFH DSEELVPLCY RCSTNNPLLN NLGNVCINCR
     QPFVFSASSY EVLHLVEFYL EDGITDEEAV ALIDLEAPRV SKWQETMSEH TQSLKLDDST
     DIIEDGDPFT AKLSFEQGGS AFVPVVLGRA ALRALSRRDV LVKRWPPPLR WQFYRSLLPD
     AAVTVCPSCL QMFHTEDYEL LILQHNCCPF CRRRIDESNQ
//