ID U3KHN6_FICAL Unreviewed; 693 AA.
AC U3KHN6;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Phospholipid phosphatase related 3 {ECO:0000313|Ensembl:ENSFALP00000014540.1};
GN Name=PLPPR3 {ECO:0000313|Ensembl:ENSFALP00000014540.1};
OS Ficedula albicollis (Collared flycatcher) (Muscicapa albicollis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Muscicapidae; Ficedula.
OX NCBI_TaxID=59894 {ECO:0000313|Ensembl:ENSFALP00000014540.1, ECO:0000313|Proteomes:UP000016665};
RN [1] {ECO:0000313|Ensembl:ENSFALP00000014540.1, ECO:0000313|Proteomes:UP000016665}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23103876; DOI=10.1038/nature11584;
RA Ellegren H., Smeds L., Burri R., Olason P.I., Backstrom N., Kawakami T.,
RA Kunstner A., Makinen H., Nadachowska-Brzyska K., Qvarnstrom A., Uebbing S.,
RA Wolf J.B.;
RT "The genomic landscape of species divergence in Ficedula flycatchers.";
RL Nature 491:756-760(2012).
RN [2] {ECO:0000313|Ensembl:ENSFALP00000014540.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the PA-phosphatase related phosphoesterase
CC family. {ECO:0000256|ARBA:ARBA00008816}.
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DR RefSeq; XP_005060153.1; XM_005060096.1.
DR AlphaFoldDB; U3KHN6; -.
DR STRING; 59894.ENSFALP00000014540; -.
DR Ensembl; ENSFALT00000014602.2; ENSFALP00000014540.1; ENSFALG00000013931.2.
DR GeneID; 101807343; -.
DR KEGG; fab:101807343; -.
DR CTD; 79948; -.
DR eggNOG; KOG3030; Eukaryota.
DR GeneTree; ENSGT00940000160280; -.
DR HOGENOM; CLU_021458_8_0_1; -.
DR OMA; GNPWEWA; -.
DR OrthoDB; 25293at2759; -.
DR Proteomes; UP000016665; Chromosome 28.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006644; P:phospholipid metabolic process; IEA:InterPro.
DR CDD; cd03384; PAP2_wunen; 1.
DR Gene3D; 1.20.144.10; Phosphatidic acid phosphatase type 2/haloperoxidase; 1.
DR InterPro; IPR036938; P_Acid_Pase_2/haloperoxi_sf.
DR InterPro; IPR000326; P_Acid_Pase_2/haloperoxidase.
DR InterPro; IPR043216; PA_PP_rel.
DR PANTHER; PTHR10165; LIPID PHOSPHATE PHOSPHATASE; 1.
DR PANTHER; PTHR10165:SF14; PHOSPHOLIPID PHOSPHATASE-RELATED PROTEIN TYPE 3; 1.
DR Pfam; PF01569; PAP2; 1.
DR SMART; SM00014; acidPPc; 1.
DR SUPFAM; SSF48317; Acid phosphatase/Vanadium-dependent haloperoxidase; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000016665};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 70..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 204..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 228..247
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 259..279
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 130..274
FT /note="Phosphatidic acid phosphatase type 2/haloperoxidase"
FT /evidence="ECO:0000259|SMART:SM00014"
FT REGION 309..340
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 523..553
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 567..676
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 662..676
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 693 AA; 74318 MW; 3F5E3F373F01635B CRC64;
MIPPKEKARA PKDSMTLLPC FYFVELPIVA SSVVTLYFLE LTDLFKPAKV GFQCHDRALS
MPYVETNEEL IPLLMLLSLA FAAPAASIMV GEGMVYCLQS RLKGRAGAEG SINAGGCNFN
SFLRRTVRFV GVHVFGLCAT ALVTDVIQLA TGYHAPFFLT VCKPNYTLLG TPCDANPYIT
QDICSGTDKH AILSARKTFP SQHATLSAFA AVYVSMYFNS IISDSTKLLK PILVFAFAIA
AGICGLTQIT QYRSHPADVY VGFLIGAGIA AYLAFHAVGN FRAPTERVPA QAPAKDALRA
LTQRGHDSVY HQNKSVSTDE LNPQARLEEA ARPVPREKNS LGSLKRASVD VDLLAPRSPM
GKENMVTFSN TLPRVNTPSM DDPARRHMTI HVPVDASRSK QLITEWKQKS LEGRSMTLAE
EAAQGRGVGE PGEEVPPSLY PTVQARSAER VAVGPRVLIQ PRPGASQLVH IPEESQAGAG
AAASAGAAVR AKWVMVAEKG GAQRVANPPR LMQVIAMSKQ QSLVSVTPKH SETSSSSTSS
DSSQYRSPSE RDSSSIITID AHAPHHPVVH LSAGNGPWEW KSGPKGPDGP DTYELGEVGK
DFHGFRPAKS AGVSPGSSVS DMEQDEPRYG SLAAIPGAAG GGGERVEAPP EGLLATASRD
STLRRKPAER DGAADSEVDL YYKKMQAGRR FKD
//
