ID U3KIW1_FICAL Unreviewed; 549 AA.
AC U3KIW1;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=LRRNT domain-containing protein {ECO:0000259|SMART:SM00013};
GN Name=AMIGO3 {ECO:0000313|Ensembl:ENSFALP00000014965.1};
OS Ficedula albicollis (Collared flycatcher) (Muscicapa albicollis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Muscicapidae; Ficedula.
OX NCBI_TaxID=59894 {ECO:0000313|Ensembl:ENSFALP00000014965.1, ECO:0000313|Proteomes:UP000016665};
RN [1] {ECO:0000313|Ensembl:ENSFALP00000014965.1, ECO:0000313|Proteomes:UP000016665}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23103876; DOI=10.1038/nature11584;
RA Ellegren H., Smeds L., Burri R., Olason P.I., Backstrom N., Kawakami T.,
RA Kunstner A., Makinen H., Nadachowska-Brzyska K., Qvarnstrom A., Uebbing S.,
RA Wolf J.B.;
RT "The genomic landscape of species divergence in Ficedula flycatchers.";
RL Nature 491:756-760(2012).
RN [2] {ECO:0000313|Ensembl:ENSFALP00000014965.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily. AMIGO family.
CC {ECO:0000256|ARBA:ARBA00005670}.
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DR RefSeq; XP_005052957.1; XM_005052900.2.
DR AlphaFoldDB; U3KIW1; -.
DR STRING; 59894.ENSFALP00000014965; -.
DR Ensembl; ENSFALT00000015030.2; ENSFALP00000014965.1; ENSFALG00000014350.2.
DR GeneID; 101812843; -.
DR KEGG; fab:101812843; -.
DR CTD; 386724; -.
DR eggNOG; ENOG502QUWU; Eukaryota.
DR GeneTree; ENSGT00950000183146; -.
DR HOGENOM; CLU_030478_0_0_1; -.
DR OMA; TPCRCPP; -.
DR OrthoDB; 5352422at2759; -.
DR Proteomes; UP000016665; Chromosome 12.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR031283; AMIGO.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000372; LRRNT.
DR PANTHER; PTHR24368; AMPHOTERIN-INDUCED PROTEIN; 1.
DR PANTHER; PTHR24368:SF62; AMPHOTERIN-INDUCED PROTEIN 3; 1.
DR Pfam; PF00560; LRR_1; 1.
DR Pfam; PF13855; LRR_8; 1.
DR SMART; SM00369; LRR_TYP; 6.
DR SMART; SM00013; LRRNT; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 3.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000016665};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 431..450
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 73..105
FT /note="LRRNT"
FT /evidence="ECO:0000259|SMART:SM00013"
FT REGION 516..549
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 517..531
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 532..549
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 549 AA; 61059 MW; 8F85DFA0859FF012 CRC64;
MLGRAKPEWG KRRETAADFF SRLTELCRRA VESFLPATMS SPVPGDPLWP RVAKLLLLLL
QLSAPRASPQ PHRCPAACIC TSDLLSCSRQ TLQRVPQALP PTTTTLDLSH NALTQLHDRW
LAALPHLETL HISHNQIRDL PPRAFHNASF LRHLDMSSNH LHAVERHYFE ALVSLEELLL
YNNRITRVDE NAFAKLSSLR KVYLSWNNLT TFPFHAVQGL GIYNLRTLDL SSNNLSSIPV
EVLAALPENI GNGLYLHNNP IRCSCPLYLM LQRWNQRGFS SVKDFSEEHT CKVSDNVPRS
LIKFLKHSRM FENCSASAED AHLSHLEVTV GQPILLTCNT SNTSNTSLPH AAATYMWITP
QHEPIRHPGN SNRSLEVYGN GSLRIAAAKP WLSGVYVGLA MNSPYNFSRM CEFNVTILYP
KAAGETFSTG LTTLLGCIVS LVLVIIYLYL TPCRCLGCCR KPAPLSPPQE CSAQSSILST
TPPATDAPNR KASANKHVVF LEPIRETQNG KIRLALGEDF PDPKHPKVLQ LKSDSESISS
VFSDTPIVS
//
