ID U3KMU9_RABIT Unreviewed; 356 AA.
AC U3KMU9;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=N-acetyl-D-glucosamine kinase {ECO:0000256|ARBA:ARBA00014974};
DE EC=2.7.1.59 {ECO:0000256|ARBA:ARBA00012122};
DE AltName: Full=GlcNAc kinase {ECO:0000256|ARBA:ARBA00031123};
GN Name=NAGK {ECO:0000313|Ensembl:ENSOCUP00000026558.2};
OS Oryctolagus cuniculus (Rabbit).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX NCBI_TaxID=9986 {ECO:0000313|Ensembl:ENSOCUP00000026558.2, ECO:0000313|Proteomes:UP000001811};
RN [1] {ECO:0000313|Ensembl:ENSOCUP00000026558.2, ECO:0000313|Proteomes:UP000001811}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thorbecke inbred {ECO:0000313|Ensembl:ENSOCUP00000026558.2,
RC ECO:0000313|Proteomes:UP000001811};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSOCUP00000026558.2}
RP IDENTIFICATION.
RC STRAIN=Thorbecke {ECO:0000313|Ensembl:ENSOCUP00000026558.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the eukaryotic-type N-acetylglucosamine kinase
CC family. {ECO:0000256|ARBA:ARBA00006198}.
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DR EMBL; AAGW02006884; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_008252481.1; XM_008254259.2.
DR AlphaFoldDB; U3KMU9; -.
DR Ensembl; ENSOCUT00000033511.2; ENSOCUP00000026558.2; ENSOCUG00000008901.4.
DR GeneID; 100347215; -.
DR CTD; 55577; -.
DR GeneTree; ENSGT00510000047418; -.
DR HOGENOM; CLU_016274_0_0_1; -.
DR OrthoDB; 3030525at2759; -.
DR Proteomes; UP000001811; Chromosome 2.
DR Bgee; ENSOCUG00000008901; Expressed in ovary and 18 other cell types or tissues.
DR ExpressionAtlas; U3KMU9; baseline.
DR GO; GO:0045127; F:N-acetylglucosamine kinase activity; IEA:UniProtKB-EC.
DR CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR Gene3D; 3.30.420.40; -; 1.
DR InterPro; IPR002731; ATPase_BadF.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR039758; NAGK_prok_euk.
DR PANTHER; PTHR12862; BADF TYPE ATPASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR12862:SF0; N-ACETYL-D-GLUCOSAMINE KINASE; 1.
DR Pfam; PF01869; BcrAD_BadFG; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001811}.
FT DOMAIN 23..289
FT /note="ATPase BadF/BadG/BcrA/BcrD type"
FT /evidence="ECO:0000259|Pfam:PF01869"
SQ SEQUENCE 356 AA; 39122 MW; 94CF5412BE56579A CRC64;
MELWQVCELG HTSKVSRTWC CRGGTRSKVL LLSEDGQILA EADGLSTNHW LIGTDKCVER
INEMVNRAKR KAGVDPLVPL RSLGLSLSGG EQEDAVRILM EELRDRFPYL SESYLITTDA
AGSIATATPD GGIVLISGTG SNCRLINPDG SESGCGGWGH MMGDEGSAYW IAHQAVKIVF
DSIDNLEAAP HDIGYVKQAM FNYFQVPDRL GILTHLYRDF DKCRFAGFCR KIAEGAQQGD
PLSRYIFRKA GEMLGRHVVA VLPEIDPVLF QGEIGLPILC VGSVWKSWEL LKEGFLLALT
QGREIQAQNS FSSFTLMKLR HSSALGGASL GARHIGHLLP MDYNVNAIAF YSYTFS
//
