ID U3SWM1_MYCAV Unreviewed; 446 AA.
AC U3SWM1;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=PPE domain-containing protein MACPPE12 {ECO:0000313|EMBL:QGZ13096.1};
DE SubName: Full=PPE family protein {ECO:0000313|EMBL:BAN84502.1};
GN Name=MACPPE12 {ECO:0000313|EMBL:BAN84502.1};
OS Mycobacterium avium subsp. hominissuis.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium avium complex (MAC).
OX NCBI_TaxID=439334 {ECO:0000313|EMBL:BAN84502.1};
RN [1] {ECO:0000313|EMBL:BAN84502.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=606MA {ECO:0000313|EMBL:BAN84502.1};
RX PubMed=24060733; DOI=10.1016/j.meegid.2013.08.010;
RA Iwamoto T., Arikawa K., Nakajima C., Nakanishi N., Nishiuchi Y.,
RA Yoshida S., Tamaru A., Tamura Y., Hoshino Y., Yoo H., Park Y.K., Saito H.,
RA Suzuki Y.;
RT "Intra-subspecies sequence variability of the MACPPE12 gene in
RT Mycobacterium avium subsp. hominissuis.";
RL Infect. Genet. Evol. 21:479-483(2014).
RN [2] {ECO:0000313|EMBL:QGZ13096.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=135-1108 {ECO:0000313|EMBL:QGZ13096.1};
RA Starkova D., Iwamoto T., Vyazovaya A., Molchanov V., Zhuravlev V.,
RA Narvskaya O.;
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:QGZ13096.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=135-1108 {ECO:0000313|EMBL:QGZ13096.1};
RA Starkova D.A., Iwamoto T., Vyazovaya A.A., Molchanov V.M., Zhuravlev V.Y.,
RA Vishnevsky B.I., Narvskaya O.V.;
RT "Single nucleotide polymorphisms in hsp65 and MACPPE12 genes of
RT Mycobacterium avium subsp. hominissuis.";
RL Russ. J. Genet. 55:544-550(2019).
CC -!- SIMILARITY: Belongs to the mycobacterial PPE family.
CC {ECO:0000256|ARBA:ARBA00010652}.
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DR EMBL; AB820314; BAN84502.1; -; Genomic_DNA.
DR EMBL; MK029416; QGZ13096.1; -; Genomic_DNA.
DR RefSeq; WP_033713215.1; NZ_LMVZ01000019.1.
DR AlphaFoldDB; U3SWM1; -.
DR Gene3D; 1.20.1260.20; PPE superfamily; 1.
DR InterPro; IPR022171; PPE_C.
DR InterPro; IPR000030; PPE_dom.
DR InterPro; IPR038332; PPE_sf.
DR InterPro; IPR018649; SHOCT.
DR PANTHER; PTHR46766; GLUTAMINE-RICH PROTEIN 2; 1.
DR PANTHER; PTHR46766:SF1; GLUTAMINE-RICH PROTEIN 2; 1.
DR Pfam; PF00823; PPE; 1.
DR Pfam; PF12484; PPE-SVP; 1.
DR Pfam; PF09851; SHOCT; 1.
DR SUPFAM; SSF140459; PE/PPE dimer-like; 1.
PE 3: Inferred from homology;
FT DOMAIN 5..161
FT /note="PPE"
FT /evidence="ECO:0000259|Pfam:PF00823"
FT DOMAIN 304..374
FT /note="PPE family C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12484"
FT DOMAIN 417..443
FT /note="SHOCT"
FT /evidence="ECO:0000259|Pfam:PF09851"
FT REGION 276..321
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 337..409
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 446 AA; 44357 MW; DDA25235DE977FF8 CRC64;
MHFAVLPPEV NSGRMYSGPG SGSMLAAASA WDELANELHV TAANIESVIS GLTSEPWQGP
SAAAVTAAAA TQVEWLTATA EQAAQTGAQL RAAATAYESA YAMTVPPSVV AANRSRLASL
VATNLLGQNT PAIAATEVAY GEMWAQDVAA MYGYAGAAQA ASRVTPFTPP QRTTNEAGMG
AQNASVAQAA GTSAGHVQSA VSNSNAMSAV PNALQNLASS SSSSSAASGL SDFSSFLNPY
NLVSLGSAFF GNGTGLIGVS GAAGFISDAE HKMTEPGAKS KAVAAPERLE PPPGSRSSGA
TTVSAGMGRA SSLGGMSVPQ GWSTAAPELR LTALQAPAAA AAPPGRPGPF GEMPLFGGAP
LMGLPGRGAA DSRDGRSSGD AGTAGRGRRA AASHGPAGAA RTASTGTTAE LREITDLLGK
LAELRATGAL TDTEFAEQKQ RLLGAR
//
