ID   U4L999_PYROM            Unreviewed;       669 AA.
AC   U4L999;
DT   11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT   11-DEC-2013, sequence version 1.
DT   27-MAR-2024, entry version 49.
DE   SubName: Full=Similar to Vacuolar segregation protein pep7 acc. no. O13786 {ECO:0000313|EMBL:CCX14992.1};
GN   ORFNames=PCON_01218 {ECO:0000313|EMBL:CCX14992.1};
OS   Pyronema omphalodes (strain CBS 100304) (Pyronema confluens).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Pezizomycetes;
OC   Pezizales; Pyronemataceae; Pyronema.
OX   NCBI_TaxID=1076935 {ECO:0000313|EMBL:CCX14992.1};
RN   [1] {ECO:0000313|EMBL:CCX14992.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS100304 {ECO:0000313|EMBL:CCX14992.1};
RC   TISSUE=Vegetative mycelium {ECO:0000313|EMBL:CCX14992.1};
RX   PubMed=24068976; DOI=10.1371/journal.pgen.1003820;
RA   Traeger S., Altegoer F., Freitag M., Gabaldon T., Kempken F., Kumar A.,
RA   Marcet-Houben M., Poggeler S., Stajich J.E., Nowrousian M.;
RT   "The genome and development-dependent transcriptomes of Pyronema confluens:
RT   a window into fungal evolution.";
RL   PLoS Genet. 9:E1003820-E1003820(2013).
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DR   EMBL; HF936108; CCX14992.1; -; Genomic_DNA.
DR   AlphaFoldDB; U4L999; -.
DR   STRING; 1076935.U4L999; -.
DR   eggNOG; KOG1842; Eukaryota.
DR   OMA; QASNFLH; -.
DR   OrthoDB; 1441111at2759; -.
DR   Proteomes; UP000018144; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   CDD; cd15761; FYVE1_Vac1p_like; 1.
DR   CDD; cd15737; FYVE2_Vac1p_like; 1.
DR   Gene3D; 4.10.860.20; Rabenosyn, Rab binding domain; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR   InterPro; IPR006642; Rad18_UBZ4.
DR   InterPro; IPR021565; Rbsn_Rab-bd.
DR   InterPro; IPR036531; Rbsn_Rab-bd_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   InterPro; IPR000306; Znf_FYVE.
DR   InterPro; IPR017455; Znf_FYVE-rel.
DR   InterPro; IPR011011; Znf_FYVE_PHD.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR23164; EARLY ENDOSOME ANTIGEN 1; 1.
DR   PANTHER; PTHR23164:SF30; LD23155P; 1.
DR   Pfam; PF01363; FYVE; 2.
DR   Pfam; PF11464; Rbsn; 1.
DR   SMART; SM00064; FYVE; 2.
DR   SMART; SM00734; ZnF_Rad18; 1.
DR   SUPFAM; SSF57903; FYVE/PHD zinc finger; 2.
DR   SUPFAM; SSF140125; Rabenosyn-5 Rab-binding domain-like; 1.
DR   PROSITE; PS50178; ZF_FYVE; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
PE   4: Predicted;
KW   DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00091}.
FT   DOMAIN          361..436
FT                   /note="FYVE-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50178"
FT   REGION          1..94
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          578..612
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        20..92
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        582..597
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   669 AA;  74132 MW;  2ACE4FDE26CE1705 CRC64;
     MASPRPTPLA VPPVSPRAAG EARQSSTAQS IQSKPPTTRP KRVLGSTATA TNFKPRSTRD
     QQTHTPSSSV SVSNARLSPS ASEVSFTSRS DVSRGPEGLV CPICSEEMMT LLQLNRHLDD
     LHAEVESFEK DDITTWFRKR MLKAKTFQPV AVLNQKLKGL DVFETNEVPA IQQQQQQQQY
     PGQTIQPYAS TTPQPDADFY VTRSHWQKSY GDDYCLDPSC QRPLGVVNGC VNCRKCGKLF
     CEEHTMYQIK LSRSAQHEPV RGYWSRVCET CYKSRVGYND HNGIHQDHTS FFTEKRKAKV
     ERQALEVHRA EKRLTRLTQL LTSPSPSPPP DQGNGFMKGI KPLLQNQRRA LEQSVVAWED
     DAKVTNCPCC TQTFSRFSLQ KHHCRVCGAV VCGDLRTGCS KEIPFDVTAP VEKPTPSTAV
     VTINIRICAP CNTTIFSKRD FEASISIQPQ YVRSYSTLVS FQTGILEQLP RFTKMVETIH
     KSKNRDKVVE AVKMKRRLID TLAKIDGVAK VIATGATDNT AEHKLRRAVA LATANWGTTV
     GMKVKTASTM LDAVVAATRP TAKQEIAARL GKPLPSPLAI DSGASSPVSS NGATTPKALM
     SPPIRDQTER EEDERREIVV VLEEQKFLVL QMLEEAKKRR RFDEVEVLAG SLDEIEAEIK
     ALGGGVLGV
//