ID U4PMS5_CAEEL Unreviewed; 551 AA.
AC U4PMS5;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 24-JAN-2024, entry version 58.
DE RecName: Full=Phosphorylase b kinase regulatory subunit {ECO:0000256|RuleBase:RU364123};
GN ORFNames=CELE_Y67D8A.2 {ECO:0000313|EMBL:CDH93399.1}, Y67D8A.2
GN {ECO:0000313|EMBL:CDH93399.1, ECO:0000313|WormBase:Y67D8A.2g};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CDH93399.1, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CDH93399.1, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CDH93399.1,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- FUNCTION: Phosphorylase b kinase catalyzes the phosphorylation of
CC serine in certain substrates, including troponin I.
CC {ECO:0000256|RuleBase:RU364123}.
CC -!- PATHWAY: Glycan biosynthesis; glycogen metabolism.
CC {ECO:0000256|RuleBase:RU364123}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364123};
CC Lipid-anchor {ECO:0000256|RuleBase:RU364123}; Cytoplasmic side
CC {ECO:0000256|RuleBase:RU364123}.
CC -!- SIMILARITY: Belongs to the phosphorylase b kinase regulatory chain
CC family. {ECO:0000256|RuleBase:RU364123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BX284604; CDH93399.1; -; Genomic_DNA.
DR RefSeq; NP_001294595.1; NM_001307666.1.
DR AlphaFoldDB; U4PMS5; -.
DR EnsemblMetazoa; Y67D8A.2g.1; Y67D8A.2g.1; WBGene00022059.
DR AGR; WB:WBGene00022059; -.
DR WormBase; Y67D8A.2g; CE49019; WBGene00022059; -.
DR HOGENOM; CLU_457285_0_0_1; -.
DR OrthoDB; 3640971at2759; -.
DR UniPathway; UPA00163; -.
DR Proteomes; UP000001940; Chromosome IV.
DR Bgee; WBGene00022059; Expressed in larva and 4 other cell types or tissues.
DR ExpressionAtlas; U4PMS5; baseline and differential.
DR GO; GO:0005964; C:phosphorylase kinase complex; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR GO; GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-UniPathway.
DR InterPro; IPR045583; KPBA/B_C.
DR InterPro; IPR008734; PHK_A/B_su.
DR PANTHER; PTHR10749; PHOSPHORYLASE B KINASE REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR10749:SF8; PHOSPHORYLASE B KINASE REGULATORY SUBUNIT BETA; 1.
DR Pfam; PF19292; KPBB_C; 1.
PE 1: Evidence at protein level;
KW Calmodulin-binding {ECO:0000256|RuleBase:RU364123};
KW Carbohydrate metabolism {ECO:0000256|RuleBase:RU364123};
KW Cell membrane {ECO:0000256|RuleBase:RU364123};
KW Glycogen metabolism {ECO:0000256|RuleBase:RU364123};
KW Lipoprotein {ECO:0000256|RuleBase:RU364123};
KW Membrane {ECO:0000256|RuleBase:RU364123};
KW Prenylation {ECO:0000256|RuleBase:RU364123};
KW Proteomics identification {ECO:0007829|EPD:U4PMS5,
KW ECO:0007829|PeptideAtlas:U4PMS5};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940}.
FT DOMAIN 272..391
FT /note="Phosphorylase b kinase regulatory subunit alpha/beta
FT C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19292"
FT REGION 475..551
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 493..545
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 551 AA; 62466 MW; FCAB11B5E779A2FC CRC64;
MEETHDNSAI FSRLSLKEGY DDDMTHEKDV TPRTDHELFQ IIEKDDMERP RLLAFAIWIL
WSRTHPDLLV HNFTLRERLE KVYRRACQLR LWWLVRYCAG RLHKAMNSLA PAITNMLVRG
KQITLGVRNR PGAREEIIVR PIAPSDLNRL LFECCPADEP QAAVFHQELI IACSDLMSHN
PQVFEGVLTI RLSWLSDAIS MLLNYVRITG ALKFSGVSTG TPPTPGTTGI PTELDFIRKL
IRTKYRREKV IEEFKKSCIY DLSPTVVKDV VTALMTRTNW HLLSSLQTRR LNGALNRMPV
NFYDRVWTIL ERSTHGIIIA DQFLPQQPTL SDMTRFELTF SYKIEAMLSR ISHPEYRQLL
VELLSIIATI LERNPEIAFT HSRIDCDSLI KKGFALFAAE EGIKDLNDLT PFYQLEGQAL
STSTATFLTK AVVEFILAGR HFSQVINIFG EGTPEEKTLP SQHHRGKMPK IAYTGRASSE
KKKRHVGGSS SSSQHHHHHQ QQQTPLLRLA TPLTPEPSSG TVTPRAITPS PLSSSLNTSG
GGGQDESCRL Q
//
