ID U4QI57_LACHE Unreviewed; 698 AA.
AC U4QI57;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=DNA methylase N-4/N-6 domain protein {ECO:0000313|EMBL:CDI42901.1};
GN ORFNames=LHCIRMBIA953_00909 {ECO:0000313|EMBL:CDI42901.1};
OS Lactobacillus helveticus CIRM-BIA 953.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactobacillus.
OX NCBI_TaxID=1226335 {ECO:0000313|EMBL:CDI42901.1, ECO:0000313|Proteomes:UP000017243};
RN [1] {ECO:0000313|EMBL:CDI42901.1, ECO:0000313|Proteomes:UP000017243}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CIRM-BIA 953 {ECO:0000313|EMBL:CDI42901.1,
RC ECO:0000313|Proteomes:UP000017243};
RA Valence F., Chuat V., Ma L., Creno S., Falentin H., Lortal S., Bizet C.,
RA Clermont D., Loux V., Bouchier C., Cousin S.;
RT "Draft Genome Sequence of five Lactobacillus helveticus strains CIRM-BIA
RT 101T, 103, 104, 951 and 953 isolated from milk product.";
RL Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the N(4)/N(6)-methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00006594}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDI42901.1}.
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DR EMBL; CBUH010000131; CDI42901.1; -; Genomic_DNA.
DR RefSeq; WP_023061693.1; NZ_CBUH010000131.1.
DR AlphaFoldDB; U4QI57; -.
DR Proteomes; UP000017243; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR GO; GO:0006306; P:DNA methylation; IEA:InterPro.
DR GO; GO:0009307; P:DNA restriction-modification system; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002941; DNA_methylase_N4/N6.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR001091; RM_Methyltransferase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR Pfam; PF01555; N6_N4_Mtase; 1.
DR PRINTS; PR00508; S21N4MTFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:CDI42901.1}; Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 149..498
FT /note="DNA methylase N-4/N-6"
FT /evidence="ECO:0000259|Pfam:PF01555"
SQ SEQUENCE 698 AA; 79376 MW; 053F8425D8D1F140 CRC64;
MAAIDDLINQ IPNVSLRERI KQEVNRLQKN KKFGLVYEEH LPEYTELYDA PIIKGSKVAL
KGQNKSDIYI VTKIINKVAT CKLIGERKIE NYQLLDLTAI AEFGDPIYPY LQQIDNICNN
SQSQLWHQLI EADNYHALQL LEYIYSGKID CIYIDPPYNT GAKDWKYNND YVDSNDEYRH
SKWLSFMEKR LKLAKKLLNP KDSTLIITID EKEYIHLGAL LEQIFPEAKM QMITTVINPK
GVSRIGEFSR VDEYIYVLMF GDSKPIQTSD SMLTLETDIK KTKSKSGTIW LPLKRSGSSS
LRTDRPNLFY PIYVDKVSGK VKKVGSPVPE NINSNDVEKI DGCDTILPIK QNGTEGRWQL
QRSTVLTELK EGTVRVTKKK NGEYILQHLN AGAKKEIENG SLKVVNKDQN GALIIERVDN
KLVTAKSVWN KASHDATTYG TNLLKKFLND RSFPYPKSLY AVKDILNLFI GNKKDSIVLD
FFAGSGTTLH AVNLLNKEDG GNRQCILVTN NEVSDSEASK LRRKGYQPGD NAWESKGIAQ
YVTWPRTVCS IIGKDIKGNT VKDEYLDGVS MSDGFATNVV YFKLGFLEKN SVALGMQLRK
LLSILWMKAG AKGKCPIIRD INSKGFYIFK ENKFAILVNE KNYAEFMTTV NEDDNISTVY
IITDSEAGYH EMISHLNVKN TYQLYKDYLD NFRINTKG
//
