ID   U4TX66_9LACO            Unreviewed;       894 AA.
AC   U4TX66;
DT   11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT   11-DEC-2013, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   RecName: Full=alpha-L-rhamnosidase {ECO:0000256|ARBA:ARBA00012652};
DE            EC=3.2.1.40 {ECO:0000256|ARBA:ARBA00012652};
GN   ORFNames=L248_2018 {ECO:0000313|EMBL:ERL65942.1};
OS   Schleiferilactobacillus shenzhenensis LY-73.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Schleiferilactobacillus.
OX   NCBI_TaxID=1231336 {ECO:0000313|EMBL:ERL65942.1, ECO:0000313|Proteomes:UP000030647};
RN   [1] {ECO:0000313|Proteomes:UP000030647}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LY-73 {ECO:0000313|Proteomes:UP000030647};
RX   PubMed=24265500;
RA   Lin Z., Liu Z., Yang R., Zou Y., Wan D., Chen J., Guo M., Zhao J., Fang C.,
RA   Yang R., Liu F.;
RT   "Whole-Genome Sequencing of Lactobacillus shenzhenensis Strain LY-73T.";
RL   Genome Announc. 1:e00972-e00913(2013).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Hydrolysis of terminal non-reducing alpha-L-rhamnose residues
CC         in alpha-L-rhamnosides.; EC=3.2.1.40;
CC         Evidence={ECO:0000256|ARBA:ARBA00001445};
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DR   EMBL; KI271584; ERL65942.1; -; Genomic_DNA.
DR   RefSeq; WP_022528885.1; NZ_KI271584.1.
DR   AlphaFoldDB; U4TX66; -.
DR   STRING; 1231336.L248_2018; -.
DR   eggNOG; COG3408; Bacteria.
DR   HOGENOM; CLU_002926_1_1_9; -.
DR   OrthoDB; 9761045at2; -.
DR   Proteomes; UP000030647; Unassembled WGS sequence.
DR   GO; GO:0030596; F:alpha-L-rhamnosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 1.50.10.10; -; 1.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   Gene3D; 2.60.420.10; Maltose phosphorylase, domain 3; 1.
DR   InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR   InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR   InterPro; IPR016007; Alpha_rhamnosid.
DR   InterPro; IPR035396; Bac_rhamnosid6H.
DR   InterPro; IPR035398; Bac_rhamnosid_C.
DR   InterPro; IPR013737; Bac_rhamnosid_N.
DR   InterPro; IPR036116; FN3_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR008902; Rhamnosid_concanavalin.
DR   PANTHER; PTHR33307; ALPHA-RHAMNOSIDASE (EUROFUNG); 1.
DR   PANTHER; PTHR33307:SF5; CELLULOSE-BINDING SDE182 NUCLEOSIDE HYDROLASE-LIKE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR   Pfam; PF05592; Bac_rhamnosid; 1.
DR   Pfam; PF17389; Bac_rhamnosid6H; 1.
DR   Pfam; PF17390; Bac_rhamnosid_C; 1.
DR   Pfam; PF08531; Bac_rhamnosid_N; 1.
DR   PIRSF; PIRSF010631; A-rhamnsds; 1.
DR   SUPFAM; SSF49265; Fibronectin type III; 1.
DR   SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT   DOMAIN          144..269
FT                   /note="Bacterial alpha-L-rhamnosidase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08531"
FT   DOMAIN          308..405
FT                   /note="Alpha-L-rhamnosidase concanavalin-like"
FT                   /evidence="ECO:0000259|Pfam:PF05592"
FT   DOMAIN          410..756
FT                   /note="Alpha-L-rhamnosidase six-hairpin glycosidase"
FT                   /evidence="ECO:0000259|Pfam:PF17389"
FT   DOMAIN          758..833
FT                   /note="Alpha-L-rhamnosidase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF17390"
SQ   SEQUENCE   894 AA;  98493 MW;  DCEEC877F87035C9 CRC64;
     MTIKAIIRIN DTTDFLFTAQ PQFSWQLVGG VNTLYQTDYT LVLAADPECR QVLWQTTRHT
     SQSLAIRLPA AQLQPATRYY ARVRVQTNQG STDWSAPVSW ADPRTAWQAA WIRPEVTAVG
     GPKGQRRPFI AQKTFTLTEP LAGRAILRLS ALGLYHAQLN GRDVGADYFR PGFTDYDQRV
     QYQSGDVTDL LCQGTNVLTI EVTAGWYSGL YGWWGARGLF GDTNALIGQL EINGRVVVAT
     DDSWTEWVGP RQYADFYNGE AYDARVQKQQ VGHMLLFPHS RAVLVPQEGP SVRVVEKITP
     RRLFRDPAGD LVLDLGQNIA GWVAFRNRHV AAPGVVTLTY GEVLDQAGNF FRENLRGADA
     QDTYRLAPND GQTYQPRFTY HGFRYVRLTG FTDAVTAADF TGIAISSLHR QTGTFTTDQP
     AVNQLQSNIT WSQRGNFVEI PTDCPQRDER AGWTADAQVF MPTANFNADT QFFIRRWLRD
     FLPSQQAQDG ALPVVIPDIL RGGFNGTSGV WGDAAVLIPW ALYCTYGDLQ ILQEQYASMR
     AWVDYVRRQG TVAGLYDTGA QLGDWLALDT PAGSYHGATD QNFVATAFFA WSTAVVAQTA
     RLLGDVPAAQ DYTQLDDTIR KAIQQTYLNG IVPKKDTQTA NVLLLQCGLV PAAERPAVAR
     HLADLIRANG HHLDTGFAGA PYLCPVLSAN GQTETAYDLL FQDDYPSWLY EVKQGATTMW
     EHWDGIKPDG SFWSSDMNSF NHYAYGSIGQ WLYETVAGIR AQRPGYQWSV IAPQPDPQRR
     LHHVRASIAT AFGLLGSEWT LSAAGTFSLT VTVPANTTAQ VVLPQGAGEE EMVQAATAGQ
     AQFTDGTLHG RSVDSFGVPF TEPVPADAEA YAVPAGALGF TVGSGTYTFS YPVQ
//