ID U4TXG3_DENPD Unreviewed; 626 AA.
AC U4TXG3;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Basement membrane-specific heparan sulfate proteoglycan core protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=D910_02115 {ECO:0000313|EMBL:ERL84688.1};
OS Dendroctonus ponderosae (Mountain pine beetle).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC Curculionidae; Scolytinae; Dendroctonus.
OX NCBI_TaxID=77166 {ECO:0000313|EMBL:ERL84688.1, ECO:0000313|Proteomes:UP000030742};
RN [1] {ECO:0000313|EMBL:ERL84688.1, ECO:0000313|Proteomes:UP000030742}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23537049; DOI=10.1186/gb-2013-14-3-r27;
RA Keeling C.I., Yuen M.M., Liao N.Y., Roderick Docking T., Chan S.K.,
RA Taylor G.A., Palmquist D.L., Jackman S.D., Nguyen A., Li M., Henderson H.,
RA Janes J.K., Zhao Y., Pandoh P., Moore R., Sperling F.A., W Huber D.P.,
RA Birol I., Jones S.J., Bohlmann J.;
RT "Draft genome of the mountain pine beetle, Dendroctonus ponderosae Hopkins,
RT a major forest pest.";
RL Genome Biol. 14:R27-R27(2013).
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DR EMBL; KB631616; ERL84688.1; -; Genomic_DNA.
DR AlphaFoldDB; U4TXG3; -.
DR STRING; 77166.U4TXG3; -.
DR Proteomes; UP000030742; Unassembled WGS sequence.
DR GO; GO:0048513; P:animal organ development; IEA:UniProt.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR CDD; cd00096; Ig; 1.
DR CDD; cd00112; LDLa; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 3.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR000034; Laminin_IV.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR023415; LDLR_class-A_CS.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR InterPro; IPR002049; LE_dom.
DR PANTHER; PTHR24270; LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED; 1.
DR PANTHER; PTHR24270:SF67; PROLOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 1-LIKE PROTEIN; 1.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF00052; Laminin_B; 1.
DR Pfam; PF00057; Ldl_recept_a; 3.
DR PRINTS; PR00261; LDLRECEPTOR.
DR SMART; SM00409; IG; 2.
DR SMART; SM00408; IGc2; 2.
DR SMART; SM00281; LamB; 1.
DR SMART; SM00192; LDLa; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR SUPFAM; SSF57424; LDL receptor-like module; 3.
DR PROSITE; PS01248; EGF_LAM_1; 1.
DR PROSITE; PS50835; IG_LIKE; 2.
DR PROSITE; PS51115; LAMININ_IVA; 1.
DR PROSITE; PS01209; LDLRA_1; 2.
DR PROSITE; PS50068; LDLRA_2; 3.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00124}; Reference proteome {ECO:0000313|Proteomes:UP000030742}.
FT DOMAIN 20..92
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 224..313
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 364..556
FT /note="Laminin IV type A"
FT /evidence="ECO:0000259|PROSITE:PS51115"
FT DISULFID 107..119
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 114..132
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 126..141
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 144..156
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 151..169
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 163..178
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 187..199
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 194..212
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 206..221
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
SQ SEQUENCE 626 AA; 68903 MW; 60BA4F87DD1FAF66 CRC64;
MRAKVEKAMF AAAVIHITIN QEVVFQCRDE GPIRARVEWK RANGAPLPPG SRDNNGRLEM
PNIKLEHGGT YVCVAKDFPL GTPGAEISVQ LHVEKVPEIY IPPPVHCYIN ESTCSNGDCI
PRNKVCDGHF DCSDGSDEIR CRQCEPNEFK CDNKKCVSAV WKCDGQDDCD DGSDERFCQA
SGPDGQCGAQ QFTCRDRQCV PRTFHCDGAP DCIDKSDEIG CTAPVIAQGP PSMITLAAGQ
TFIITCRAVG VPTPQIMWRL NWNHVPPKCR MTSENGFGTL TCENIQIEDQ GAYSCEALSA
IKTVFASPDT ILTVTRQAFC PAGYFNVDAR VENECIKCFC FGHSSSCRSA DLFIFQFQPP
FDALKLLGAR IDPRTGVVDI RDEPIYKGVE PQLWNIGANG VATSLPKYAE LNQPDVVPYF
ALPENYHGNQ LKSYGGYLKY TVRHGNTGRP VEGPDVILTG NNYVLLHESR DPPAPFQAEE
KRVRFFDGDW TIKSASQRPR PASREEVMMA LEDVSQILIK LAYSSDGLLN TTLTNIEMDS
AAVPDSGLGV ANYVEECSCP VGYTGTSCEN CAEGYVRHNS GQWLGQCYRE PQTCPPGSYF
DGRECQVCPC PYTSPSNQPS FGRNSS
//
