ID U4TY50_DENPD Unreviewed; 870 AA.
AC U4TY50;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE RecName: Full=Peptidase S9 prolyl oligopeptidase catalytic domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=D910_03950 {ECO:0000313|EMBL:ERL86544.1};
OS Dendroctonus ponderosae (Mountain pine beetle).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC Curculionidae; Scolytinae; Dendroctonus.
OX NCBI_TaxID=77166 {ECO:0000313|EMBL:ERL86544.1, ECO:0000313|Proteomes:UP000030742};
RN [1] {ECO:0000313|EMBL:ERL86544.1, ECO:0000313|Proteomes:UP000030742}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23537049; DOI=10.1186/gb-2013-14-3-r27;
RA Keeling C.I., Yuen M.M., Liao N.Y., Roderick Docking T., Chan S.K.,
RA Taylor G.A., Palmquist D.L., Jackman S.D., Nguyen A., Li M., Henderson H.,
RA Janes J.K., Zhao Y., Pandoh P., Moore R., Sperling F.A., W Huber D.P.,
RA Birol I., Jones S.J., Bohlmann J.;
RT "Draft genome of the mountain pine beetle, Dendroctonus ponderosae Hopkins,
RT a major forest pest.";
RL Genome Biol. 14:R27-R27(2013).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB631820; ERL86544.1; -; Genomic_DNA.
DR AlphaFoldDB; U4TY50; -.
DR STRING; 77166.U4TY50; -.
DR Proteomes; UP000030742; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 2.140.10.30; Dipeptidylpeptidase IV, N-terminal domain; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR001375; Peptidase_S9.
DR InterPro; IPR002469; Peptidase_S9B_N.
DR PANTHER; PTHR11731:SF187; INACTIVE DIPEPTIDYL PEPTIDASE 10-LIKE PROTEIN; 1.
DR PANTHER; PTHR11731; PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED; 1.
DR Pfam; PF00930; DPPIV_N; 1.
DR Pfam; PF00326; Peptidase_S9; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF82171; DPP6 N-terminal domain-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030742};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 81..108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 185..588
FT /note="Dipeptidylpeptidase IV N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00930"
FT DOMAIN 664..856
FT /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT /evidence="ECO:0000259|Pfam:PF00326"
SQ SEQUENCE 870 AA; 99475 MW; 34AD0F0C22144F36 CRC64;
MFQPAGAPPH NAKIATSYST NELLEIHIGY KDPQALTRYL NILMKLSRRY LERNIMKLPS
MFHTSEQDME LALHDDEGHN WWSIIFSLLV IGLVISGIIA AIFLVGYVDE LLYWHGERMK
LEQYLQGELT PKRLPSSWIS SSHFVFQADD GSLAILDTDK NFTVSVLVTN HTLRQLNVRG
YQCSKNFKYV LFQHNVKTVF RQSCTAHYTI YDVNKDHHIP VRFESSPKAQ PERLQYVSWL
RDTTSLLIIF NNDIYYRHSP EDETNTRLTF TGQPDVVFNG VPDWLYQEDV LQSQEALWPS
YDGTHLLYAT FNDTEVGILN FPWFQTEAVL AGGKASNRPM LFPGSKSIRY PTPGTPIPQV
QLWVLDISNL TNLENYQVMP PNALEGQDYY MTSAGWIGQK NTEVSVVWIN RAQNLSIVSA
CLAPNWTCIE SHTERSLERA WLEVQEHPIF SPDGDSFLML AHVQEGRRET YTHIKHITVT
QQHIAVLSHG PHEVSKILAW DTTSHLIWYL ATEPHKAGQQ HLYVSQDPTT DDPRRIESYC
ITCELGDVLW SSRFLYGNCT HFNAIISPQS DNYRAPFYVL QCEGPGLPLA GMHNSTSHKL
LKILYDTRIG HGVLLQDLAM PKKRSFEVPL PQGSLAEVQL LLPPSWREEL RDAAYPVVVE
VHCDVVYIKL DVRGSRGRAD KALYRQLGGI EVQDQISAID YLLNKDHKYH KYLDKTRIGI
WGWGYGGYVT SMVLGMGNQQ KVFKCGIAVN PITDWLYYNS AFTEKVLGLP TENYKGYVQA
DATQRAKNIP RKSFFLLHGM ADLTAPYQHS VLLSRALAEH GVLFRYQSYP DEGHELSGVL
EHVYSSMQNF FEECLKLDTE ERELPATEDT
//
