ID U4U2L0_DENPD Unreviewed; 2013 AA.
AC U4U2L0;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=Myosin motor domain-containing protein {ECO:0000259|PROSITE:PS51456};
GN ORFNames=D910_05507 {ECO:0000313|EMBL:ERL88119.1};
OS Dendroctonus ponderosae (Mountain pine beetle).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC Curculionidae; Scolytinae; Dendroctonus.
OX NCBI_TaxID=77166 {ECO:0000313|EMBL:ERL88119.1, ECO:0000313|Proteomes:UP000030742};
RN [1] {ECO:0000313|EMBL:ERL88119.1, ECO:0000313|Proteomes:UP000030742}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23537049; DOI=10.1186/gb-2013-14-3-r27;
RA Keeling C.I., Yuen M.M., Liao N.Y., Roderick Docking T., Chan S.K.,
RA Taylor G.A., Palmquist D.L., Jackman S.D., Nguyen A., Li M., Henderson H.,
RA Janes J.K., Zhao Y., Pandoh P., Moore R., Sperling F.A., W Huber D.P.,
RA Birol I., Jones S.J., Bohlmann J.;
RT "Draft genome of the mountain pine beetle, Dendroctonus ponderosae Hopkins,
RT a major forest pest.";
RL Genome Biol. 14:R27-R27(2013).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; KB632028; ERL88119.1; -; Genomic_DNA.
DR Proteomes; UP000030742; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0030017; C:sarcomere; IEA:UniProt.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:InterPro.
DR Gene3D; 1.20.5.340; -; 6.
DR Gene3D; 1.20.5.370; -; 4.
DR Gene3D; 1.20.58.530; -; 7.
DR Gene3D; 1.20.58.60; -; 1.
DR Gene3D; 3.30.70.1590; -; 2.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 4.10.270.10; Myosin, subunit A; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR002928; Myosin_tail.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014751; XRCC4-like_C.
DR PANTHER; PTHR45615:SF40; MYOSIN HEAVY CHAIN, MUSCLE-RELATED; 1.
DR PANTHER; PTHR45615; MYOSIN HEAVY CHAIN, NON-MUSCLE; 1.
DR Pfam; PF00612; IQ; 1.
DR Pfam; PF00063; Myosin_head; 7.
DR Pfam; PF01576; Myosin_tail_1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00015; IQ; 1.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF90257; Myosin rod fragments; 6.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 8.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 5.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|PROSITE-ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Muscle protein {ECO:0000256|ARBA:ARBA00023179};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000030742};
KW Thick filament {ECO:0000256|ARBA:ARBA00022433}.
FT DOMAIN 1..113
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 115..173
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 225..280
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 282..337
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 339..830
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 603..625
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 945..991
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1706..1727
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1876..1895
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1973..2013
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 945..974
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 975..991
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1707..1725
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2013 AA; 232781 MW; 118B2FDD1A61C23D CRC64;
MGHDFTYTQR FKHIAKNFFN HHMFVLEQEE YTREGITWVF IDFGMDLAAC IELIEKYNGF
EQLCINFTNE KLQQFFNHHM FVLEQEEYKI EGINWVFIDF GMDLAACIEL IEKFNGFEQL
CINFTNEKLQ QFFNHHMFVL EQEEYKTEGI NWVFIDFGMD LAACIELIEK VIGREWVVSS
LACRMVPSQS IDWSCRIHRP TKNRRLLSVL VNVLCSQIPD STTFNSFEQL CINFTNEKLQ
QFFNHHMFVL EQEEYKIEGI DWVFIDFAMD LAACIELIEK FNSFEQLCIN FTNEKLQQFF
NHHMFVLEQE EYKIEGIEWT FIDFGLDLAA CIELIEKFNS FEQLCINFTN EKLQQFFNHH
MFVLEQEEYK REGIEWAFID FGMDLAACIE LIEKYNGFNQ LCINYSNEKL QQFYNHHMFI
LEQEQYKIEG VPWKFIDFGL DLQACIDLIE KPMGILSILE EESMFPKATD QTFVEKLNTN
HLGKSPNYQK PKPPKPGQQA AHFTLGHYAG NVPYNITGWL EKNKDPLNDT VVDLFKKGTN
KLLCEIFSDH PGQSGGAEAK GAKRTKGSAF QTVSAMYREA VERRVVVSRL YLPPTRYIIE
EQLNNLMSTL RATQPHFVRC IIPNELKQPG LIDSHLVMHQ LTCNGVLEGI RICRKGFPNR
MVYPDFKLRY MILAPATMAA EKEAKEAARK CLEEIGLDPD SYRVGHTKAR LSCPCLKSHC
LVRFAAPCTM NYSPYKILNP SGASKEPDTK KCADIILQAT GLDSELYRLG HTKVSYKILA
PSSIKASTTP EKAAEIILDA IALEKEQFRM GKTKVFFRAG VLGQMEELRD ERLGKIVTWM
QSWVRGYLSR KEFKRLQEQR LALQVCQRNL RKYLKLRTWP WYKLWQKVRP LLNVTRIEDE
IAKLEEKAAK AQEAYEREAK AKKELETLYA KLLTEKTDLL STLEGEKGSL SETQERANKL
QAQKSDLEAQ LQETQDRLSQ EEDSRNQLTQ QKKKLEQEIN GFKKDIEDLE LNLQKSEQDK
ATKDHQIRNL NDEIAHQDEL INKLNKEKKV GGENNQKISE ELQAAEDKVN HLNKVKAKLE
QTLDELEDSL EREKKLRGDV EKSKRKVEGD LKLTQEGVAD LERNKKELEQ TIQRKDKEIS
SLTAKLEDEQ SVVGKTQKQI KELQARIEEL EEEVEAERQA RAKAEKQRAD LARELEELGE
RLEEAGGATS AQIELNKKRE AELAKLRRDL EESNIQHEGT LANLRKKHND AVSEMGEQID
QLNKLKAKAE KEKAQYFGEL NDLRASVDHL ANEKAAIEKV SKQLQQQLND VQGKLDETNR
TLNDFDAAKK KLSIENSDLL RQLEEAESQV SQLSKIKVSL TTQLEDTKRL ADEESRERAT
LLGKFRNLEH DLDNIREQVE EEAEAKADIQ RQLSKANAES QLWRQKYESE GVARSEELEE
AKRKLQARLA EAEETIESLN QKVVALEKTK QRLATEVEDL QLEVDRATAI ANAAEKKQKA
FDKIIGEWKL KVDDLAAELD ASQKECRNYS TELFRLKGAY EEGQEQLEAV RRENKNLADE
VKDLLDQIGE GGRNIHEIEK ARKRLEAEKD ELQAALEEAE AALEQEENKV LRSQLELSQV
RQEIDRRIQE KEEEFENTRK NHQRALDSMQ ASLEAEAKGK AEALRMKKKL EADINELEIA
LDHANKANAE AQKTIKRYQQ QLKDTQQALE EEQRARDEAR EQLGISERRA NALQNELEES
RTLLEQSDRA RRQAEQELGD AHEQLNDLAA QNASMSAAKR KLETELQTLH SDLDELLNEA
KNSEEKAKKA MVDAARLADE LRAEQDHAQT QEKLRKALET QIKDLQVRLD EAEANALKGG
KKAIAKLEQR VRELENELDG EQRRHADAQK NLRKSERRIK ELSFQAEEDR KNHERMQDLV
DKLQQKIKTY KRQIEEAEEI AALNLAKFRK AQQELEEAEE RADLAEQAIA KFRAKGRAGS
SARGQSPAPR QRPQLGEGGL FPPRFDLAPE GDY
//
