ID U4U6Y6_DENPD Unreviewed; 1547 AA.
AC U4U6Y6;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=CAP-Gly domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=D910_03140 {ECO:0000313|EMBL:ERL85725.1};
OS Dendroctonus ponderosae (Mountain pine beetle).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC Curculionidae; Scolytinae; Dendroctonus.
OX NCBI_TaxID=77166 {ECO:0000313|EMBL:ERL85725.1, ECO:0000313|Proteomes:UP000030742};
RN [1] {ECO:0000313|EMBL:ERL85725.1, ECO:0000313|Proteomes:UP000030742}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23537049; DOI=10.1186/gb-2013-14-3-r27;
RA Keeling C.I., Yuen M.M., Liao N.Y., Roderick Docking T., Chan S.K.,
RA Taylor G.A., Palmquist D.L., Jackman S.D., Nguyen A., Li M., Henderson H.,
RA Janes J.K., Zhao Y., Pandoh P., Moore R., Sperling F.A., W Huber D.P.,
RA Birol I., Jones S.J., Bohlmann J.;
RT "Draft genome of the mountain pine beetle, Dendroctonus ponderosae Hopkins,
RT a major forest pest.";
RL Genome Biol. 14:R27-R27(2013).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center, centrosome {ECO:0000256|ARBA:ARBA00004300}. Cytoplasm,
CC perinuclear region {ECO:0000256|ARBA:ARBA00004556}.
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DR EMBL; KB631743; ERL85725.1; -; Genomic_DNA.
DR STRING; 77166.U4U6Y6; -.
DR MEROPS; C67.A01; -.
DR Proteomes; UP000030742; Unassembled WGS sequence.
DR GO; GO:0005680; C:anaphase-promoting complex; IEA:InterPro.
DR GO; GO:0005813; C:centrosome; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0004843; F:cysteine-type deubiquitinase activity; IEA:InterPro.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR Gene3D; 2.30.30.190; CAP Gly-rich-like domain; 2.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR007192; APC8.
DR InterPro; IPR036859; CAP-Gly_dom_sf.
DR InterPro; IPR000938; CAP-Gly_domain.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR001394; Peptidase_C19_UCH.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR028889; USP_dom.
DR PANTHER; PTHR12558; CELL DIVISION CYCLE 16,23,27; 1.
DR PANTHER; PTHR12558:SF10; CELL DIVISION CYCLE PROTEIN 23 HOMOLOG; 1.
DR Pfam; PF04049; ANAPC8; 1.
DR Pfam; PF01302; CAP_GLY; 2.
DR Pfam; PF13414; TPR_11; 1.
DR Pfam; PF13181; TPR_8; 2.
DR Pfam; PF00443; UCH; 1.
DR SMART; SM01052; CAP_GLY; 2.
DR SMART; SM00028; TPR; 8.
DR SUPFAM; SSF74924; Cap-Gly domain; 2.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50245; CAP_GLY_2; 1.
DR PROSITE; PS50005; TPR; 3.
DR PROSITE; PS50235; USP_3; 1.
PE 4: Predicted;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Reference proteome {ECO:0000313|Proteomes:UP000030742};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT REPEAT 238..271
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 306..339
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 340..373
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 708..745
FT /note="CAP-Gly"
FT /evidence="ECO:0000259|PROSITE:PS50245"
FT DOMAIN 1167..1506
FT /note="USP"
FT /evidence="ECO:0000259|PROSITE:PS50235"
FT REGION 906..934
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1547 AA; 176598 MW; 426D8775AFB8E4B3 CRC64;
MDISDLKLDL SKCKRDLLTG IRECSERGLL YAVKWLAEIN FALDHIEPAP EDVPASSGDL
GSEFSTYLMA KSYLSLKEYD RCAYFLKNCL TAKARFLHYY ARYMAIEKKD MTEMNCPPDP
RQTSALKALC TELKNEFYEN KLDGYCSYVY GIVLKKMDLH YLAANVFVRA VQEEPLLWSA
WYELGKLPSD KSQDINTQLP DHWMKYFYAA HTYLEQLKND EAVEIYQKLQ QLGFQNSTYI
LSQIALGSHN NRKLQEAIEM FQKILQIDPY RLDNLDTYSN LLYVLENKTD LAHLAHKVVE
IDKYRVETCC VIGNYYSLRS DHAKAVLYFK RALNLNPHFL SAWTLMGHEY MEMKNINAAI
QSYRYAIEIN SRDYRAWYGL GQTYEILKMP FYCLYYYKQA QHLKPNDSRM IIALGETYEK
LDKTENALKC YYKACSVGDI EGSGLIKLAK LYDKLNDTEN AAAVFIEYCV REEDKKEKVI
DEQPEYYNAL QYLANYYLRK GQLDDAYTYA YKCIECEETK EQGKALLKAI AAKRIEHDDV
EHDPEVNISV VDMSMDYSMK NDDSSMNLTS SAKMGARECV YGIFQRNDLL KDTVRGESAR
TVLLGQICII EGFLKEGVLQ VRLLKDGATW DSHTFISDSE QVVIPICDKL WPYIASISSP
QERVKFARDK VLCEKLRMVD LGTTVGFIDS TDVKLGTVRY KGNIKGLGYG FGLELNEKKP
GNKCGGHNAG YQYFQCLPGK GLFTTIEKII PTYKTSEKEG LPPKPSQVPE LDNLMRQNLS
NLTNGALEKP AREEIVTKYG EYSKKLSTPA KNTQLNHNLK SSLSLQNILE VEGGTVNTNN
DFDQNTIIQP DRSQLMNVEK LKNKSDMDLY DLIGNSWTNG ELVKPDTYSS LRKKLDKNDN
IKETYNSLSN SNSTLSSNGT LTKSSRNKSM NPLTHLLDNG GTLKKSKFYT DGLENGLDKG
GGKTNTKKVE NGKKACAFFD RDFNPLPLSV IELNESEPDH QHTLKDRKLI EHHAGKPTAQ
FYIVEKSKYT DPPVGASNDL VVGSLVEVET DVTDQPLYGV IRWMGLDIEN NFILVGIELE
EELPADLPLT LTDGTHNGER FFKCSTDRAF FVPLARCRKD PRFQVPTTPV HQAAASDFVE
CPVIPGAVAP LCMPTEEDVQ AVCGKYRGIQ GHHNSCYLDV TLFAMFTYTA VFDSLLFRPK
NQNDIADYDE NQLSFFMIKA VLSLQVQRVL REEIVNPLRK NLYVSADNVM KLRRLLDRLS
SVSGLTSEEK DPEEFLNSLL AQILKAEPFL KLNSGQTAFH YQLFVEKDAE LTLPTVQQLF
EQSFLTSDIK LTEVPSCLII QMPRFGKNYK MYPRILPSQL LDVTDVIEGS PRQCIVCGKL
AIWECKECFA ECASTAGLES TAFCTECLKT AHKHERRQRH KPKQLNVGED FLAMQEQYRP
PRLFMELFAV ICIETSHYVT FVKCGVGHEA PWCFFDSMAD RKGERDGYNI PEMVACPDIS
LWLSDEALCR QFHEEFPNDR HLPEHARRLL CDAYICMYQS SDVMMYR
//
