ID   U4UM90_DENPD            Unreviewed;       481 AA.
AC   U4UM90;
DT   11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT   11-DEC-2013, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=transketolase {ECO:0000256|ARBA:ARBA00013152};
DE            EC=2.2.1.1 {ECO:0000256|ARBA:ARBA00013152};
DE   Flags: Fragment;
GN   ORFNames=D910_11513 {ECO:0000313|EMBL:ERL94232.1};
OS   Dendroctonus ponderosae (Mountain pine beetle).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC   Curculionidae; Scolytinae; Dendroctonus.
OX   NCBI_TaxID=77166 {ECO:0000313|EMBL:ERL94232.1, ECO:0000313|Proteomes:UP000030742};
RN   [1] {ECO:0000313|EMBL:ERL94232.1, ECO:0000313|Proteomes:UP000030742}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=23537049; DOI=10.1186/gb-2013-14-3-r27;
RA   Keeling C.I., Yuen M.M., Liao N.Y., Roderick Docking T., Chan S.K.,
RA   Taylor G.A., Palmquist D.L., Jackman S.D., Nguyen A., Li M., Henderson H.,
RA   Janes J.K., Zhao Y., Pandoh P., Moore R., Sperling F.A., W Huber D.P.,
RA   Birol I., Jones S.J., Bohlmann J.;
RT   "Draft genome of the mountain pine beetle, Dendroctonus ponderosae Hopkins,
RT   a major forest pest.";
RL   Genome Biol. 14:R27-R27(2013).
CC   -!- COFACTOR:
CC       Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC         Evidence={ECO:0000256|ARBA:ARBA00001913};
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DR   EMBL; KB632384; ERL94232.1; -; Genomic_DNA.
DR   AlphaFoldDB; U4UM90; -.
DR   STRING; 77166.U4UM90; -.
DR   Proteomes; UP000030742; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   CDD; cd02012; TPP_TK; 1.
DR   Gene3D; 3.40.50.920; -; 1.
DR   Gene3D; 3.40.50.970; -; 1.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   InterPro; IPR033248; Transketolase_C.
DR   InterPro; IPR005474; Transketolase_N.
DR   PANTHER; PTHR43195:SF1; FI06132P-RELATED; 1.
DR   PANTHER; PTHR43195; TRANSKETOLASE; 1.
DR   Pfam; PF02780; Transketolase_C; 1.
DR   Pfam; PF00456; Transketolase_N; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
DR   SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000030742}.
FT   DOMAIN          24..255
FT                   /note="Transketolase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00456"
FT   DOMAIN          351..471
FT                   /note="Transketolase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02780"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:ERL94232.1"
FT   NON_TER         481
FT                   /evidence="ECO:0000313|EMBL:ERL94232.1"
SQ   SEQUENCE   481 AA;  52058 MW;  1BF8F04E3C04C9E4 CRC64;
     LGACANLNIS TQQKLQLYLK HYIHPTSCSS IGEILSVLFF HTMRYKVSAP RDPSSDRFVL
     SKGHAAPALY AAWAEAGLFS ISDLQNLRKF KSDLEGHPTP RLNFIDVGTG SLGQGLAIAG
     GMAYVGKYFD KASYRVYCLI GDGESAEGSI WESVHFASYY KLDNLCIIID VNRLGQSQET
     SIGHDVESYR KKMEAFGTEA IIVDGHDVEE LVKAFHSASA TKGKPTAIIA KTLKGKNFPK
     IENLENWHGK PLGVESDVVV NHLKGLLQNP GPLQVHPQKP LKEDAPTVDI TNIRLSSPPN
     YKLGDQIATR VAYGTALVKI AQNNPRVIAL DGDMKNSTFS EKLLHYDVGK ANVVLSSPKD
     QVVLIGAGVT LQESLSAAKE LAQAGIGARV IDPFTVKPLD KETIIKNIKD VGGRAVVTED
     HYYQGGLGEA VIAALAMEKD IIVKHLAVGE LPRSGPPNAL LQYYGISAKH ISSAAQDILK
     L
//