ID U4UN74_DENPD Unreviewed; 402 AA.
AC U4UN74;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=TGF-beta family profile domain-containing protein {ECO:0000259|PROSITE:PS51362};
DE Flags: Fragment;
GN ORFNames=D910_12800 {ECO:0000313|EMBL:ERL95539.1};
OS Dendroctonus ponderosae (Mountain pine beetle).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC Curculionidae; Scolytinae; Dendroctonus.
OX NCBI_TaxID=77166 {ECO:0000313|EMBL:ERL95539.1, ECO:0000313|Proteomes:UP000030742};
RN [1] {ECO:0000313|EMBL:ERL95539.1, ECO:0000313|Proteomes:UP000030742}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23537049; DOI=10.1186/gb-2013-14-3-r27;
RA Keeling C.I., Yuen M.M., Liao N.Y., Roderick Docking T., Chan S.K.,
RA Taylor G.A., Palmquist D.L., Jackman S.D., Nguyen A., Li M., Henderson H.,
RA Janes J.K., Zhao Y., Pandoh P., Moore R., Sperling F.A., W Huber D.P.,
RA Birol I., Jones S.J., Bohlmann J.;
RT "Draft genome of the mountain pine beetle, Dendroctonus ponderosae Hopkins,
RT a major forest pest.";
RL Genome Biol. 14:R27-R27(2013).
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
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DR EMBL; KB632432; ERL95539.1; -; Genomic_DNA.
DR AlphaFoldDB; U4UN74; -.
DR STRING; 77166.U4UN74; -.
DR Proteomes; UP000030742; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR CDD; cd13752; TGF_beta_INHB; 1.
DR Gene3D; 2.60.120.970; -; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR015615; TGF-beta-rel.
DR InterPro; IPR017948; TGFb_CS.
DR PANTHER; PTHR11848:SF294; DAWDLE, ISOFORM A; 1.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR PRINTS; PR00669; INHIBINA.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00250; TGF_BETA_1; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 3: Inferred from homology;
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354};
KW Reference proteome {ECO:0000313|Proteomes:UP000030742};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 284..402
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
FT NON_TER 402
FT /evidence="ECO:0000313|EMBL:ERL95539.1"
SQ SEQUENCE 402 AA; 46020 MW; EC5182BB6F82AEE6 CRC64;
MRIFSAMYRI MLTLVYIFVL SGSVRYVAGG IFPSSFYFRS VTQSEIPQEN SVDSEIDDPD
TVGTISEADF TALRIEYIKN QILKKLRLKE KPQITIADLP KPIKENENLL PNQDTNFFSR
YDDDFYGKTT QAVVLPYEDE ARCLRKVNYP SACLPFQMPN DIHSSDVSTA ELWFHKKADI
MDAHNQTFII YEVAHWDTNK SFQKTNPIAI RDTNIKEGWL KVDVTYVVKN WLDFQDSPIH
AINVLCKTCG LDKSQSPVSF SGDLKPFLII YTHSQQRRSL MHRRPKRSSE CKDSPNECCR
ESLYVSFAEI GWNDWIIKPE GYNAFFCRGS CTTPTAIMNS ATHHNSILQK VMGKNNQRGS
RPELTPCCAA TQFQQLHLIY MDGNKTLTTK SLSNMIVETC AC
//
