ID U5D3M1_AMBTC Unreviewed; 464 AA.
AC U5D3M1;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE RecName: Full=Rho-GAP domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=AMTR_s00057p00129680 {ECO:0000313|EMBL:ERN16845.1};
OS Amborella trichopoda.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Amborellales; Amborellaceae; Amborella.
OX NCBI_TaxID=13333 {ECO:0000313|EMBL:ERN16845.1, ECO:0000313|Proteomes:UP000017836};
RN [1] {ECO:0000313|Proteomes:UP000017836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24357323;
RG Amborella Genome Project;
RT "The Amborella genome and the evolution of flowering plants.";
RL Science 342:1241089-1241089(2013).
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DR EMBL; KI392405; ERN16845.1; -; Genomic_DNA.
DR RefSeq; XP_006855378.1; XM_006855316.2.
DR AlphaFoldDB; U5D3M1; -.
DR STRING; 13333.U5D3M1; -.
DR EnsemblPlants; ERN16845; ERN16845; AMTR_s00057p00129680.
DR GeneID; 18445173; -.
DR Gramene; ERN16845; ERN16845; AMTR_s00057p00129680.
DR KEGG; atr:18445173; -.
DR eggNOG; KOG4270; Eukaryota.
DR HOGENOM; CLU_031591_0_1_1; -.
DR OrthoDB; 5480623at2759; -.
DR Proteomes; UP000017836; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00132; CRIB; 1.
DR CDD; cd00159; RhoGAP; 1.
DR Gene3D; 3.90.810.10; CRIB domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR000095; CRIB_dom.
DR InterPro; IPR036936; CRIB_dom_sf.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR044785; RopGAP1-5.
DR PANTHER; PTHR23177; MKIAA1688 PROTEIN; 1.
DR PANTHER; PTHR23177:SF35; RHO GTPASE-ACTIVATING PROTEIN GACA; 1.
DR Pfam; PF00786; PBD; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00285; PBD; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50108; CRIB; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000017836}.
FT DOMAIN 67..80
FT /note="CRIB"
FT /evidence="ECO:0000259|PROSITE:PS50108"
FT DOMAIN 112..292
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 297..335
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 390..464
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 314..330
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 392..406
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 419..436
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 448..464
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 464 AA; 51615 MW; E5DCE06AA4ECC1FE CRC64;
MAQVVMVSKL CPGRGNSGEV GKERGDQRED ESAQISLLAL LLDTFRRSLV SCRVREEGEK
PQRQMEIGWP TNVRHVAHVT FDRFNGFLGL PVEFETEVPR KVPSASASVF GVSAESMQCS
YDSKGNSVPT ILLLLQERLY AQGALKAEGI FRINPENGQE EHLRDQLNKG IVPHDTDVHC
LAGLIKAWFR ELPSGVLDGL SPEQVLQCNT EEECLELVKL LLPTQAALLN WAVNLMTDVV
EEEEFNKMNA RNIAMVFAPN MTQMADPLTA LMHAVQVMNL LKTLILRSLR ARQETETGGY
SPFFSSPDQH AHDEDENDDA DFDDDYDGFD SQQESVGMSC ELRASDYDEE EGHDSPECRD
GGEDIECFLR SLNEKEAHLN EPDLLGRKIG SDCSISPSSG SSSRASMRIE KPLKLSEVNL
NVESKTSIPE SKNESSITSV EESEESSEEI YSASKKKCSM EICR
//
