ID U5E9M7_NOCAS Unreviewed; 800 AA.
AC U5E9M7;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Arylsulfatase {ECO:0000313|EMBL:GAD86807.1};
GN Name=astA {ECO:0000313|EMBL:GAD86807.1};
GN ORFNames=NCAST_33_01850 {ECO:0000313|EMBL:GAD86807.1};
OS Nocardia asteroides NBRC 15531.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=1110697 {ECO:0000313|EMBL:GAD86807.1, ECO:0000313|Proteomes:UP000017048};
RN [1] {ECO:0000313|EMBL:GAD86807.1, ECO:0000313|Proteomes:UP000017048}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 15531 {ECO:0000313|EMBL:GAD86807.1,
RC ECO:0000313|Proteomes:UP000017048};
RX PubMed=24884595; DOI=10.1186/1471-2164-15-323;
RA Komaki H., Ichikawa N., Hosoyama A., Takahashi-Nakaguchi A., Matsuzawa T.,
RA Suzuki K., Fujita N., Gonoi T.;
RT "Genome based analysis of type-I polyketide synthase and nonribosomal
RT peptide synthetase gene clusters in seven strains of five representative
RT Nocardia species.";
RL BMC Genomics 15:323-323(2014).
CC -!- SIMILARITY: Belongs to the sulfatase family.
CC {ECO:0000256|ARBA:ARBA00008779}.
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DR EMBL; AB685274; BAO98993.1; -; Genomic_DNA.
DR EMBL; BAFO02000033; GAD86807.1; -; Genomic_DNA.
DR AlphaFoldDB; U5E9M7; -.
DR STRING; 1824.SAMN05444423_1011770; -.
DR eggNOG; COG3119; Bacteria.
DR Proteomes; UP000017048; Unassembled WGS sequence.
DR GO; GO:0008484; F:sulfuric ester hydrolase activity; IEA:UniProt.
DR CDD; cd16025; PAS_like; 1.
DR Gene3D; 3.30.1120.10; -; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR024607; Sulfatase_CS.
DR InterPro; IPR000917; Sulfatase_N.
DR PANTHER; PTHR42693:SF33; ARYLSULFATASE; 1.
DR PANTHER; PTHR42693; ARYLSULFATASE FAMILY MEMBER; 1.
DR Pfam; PF00884; Sulfatase; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
DR PROSITE; PS00523; SULFATASE_1; 1.
DR PROSITE; PS00149; SULFATASE_2; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000017048}.
FT DOMAIN 55..475
FT /note="Sulfatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00884"
FT REGION 27..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 290..313
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 800 AA; 87923 MW; 54CAB255D1512515 CRC64;
MHITLVTSGY VTFTASMPVP PHARGYESFG GTAGRTSADS TPEWTSPPAA PAGAPNIVVV
LVDDMGYSDI GPFGSEIETP TLDRLAATGV RLSNYHTTPL CSPSRAALLT GINSHRAGFG
FVANADPGYP GLRLELADDV LTLPEILRGN GYATYAVGKW HLVRDATMNP SAHRDSWPTQ
RGFDRYYGSL EGLNSFYYPN QLVSDSSVVD VEEYPEGYYL TDDLTDKALS YIKDLRAHDA
TKPFFLYFAH VAMHGPLQAK AEDQAKYRGR YAEGWDELRR KRFAEQLAQG LFPPGTEQKP
RNTEPGYEAA EWDSLSAEEQ RRYAKYMEVY AGMVDSIDQS LGRIVDLLTE LGELDNTIIV
FTSDNGGTAE GGPEGTRSYF AEFAHIDDPD WIGDIPHDED LIGTAKLGVH YPRGWGQASN
TPFRFYKGQT FAGGVRVPLV VSWPKGLPRT GTDSGIRHEY AYVTDLAPTL LELAGLTRPS
VRNGLPAKEF DGVSAAELLR DPAAPTRHTE QYSEMTGHRG FYRDGWKLLS LYEAGADLDA
PHWQLFDVRA DPTELHDLSE RFPDKAAELA AAWDESAWAN TVFPLLSRAD LFRRRPEEAR
FAAPVRVLPG TPTLERYRSQ RLIAYRDFTI TVELTGASSS RHGARPTGDA GYRPGEEGVL
VAHGDPLGGY LLYIENGAVT LGVNSYGRYA AVTAPVPTGT REITVRAAIR PRLRWDFVVE
VDGSAVAELT DQVQLVGMAP WTGISVGVDA RGPVSWELRE RRGPFRYTGS LRAVTYTPGP
IQVPQATIDA VEHEAEYVAE
//
