ID U5EF66_9DIPT Unreviewed; 97 AA.
AC U5EF66;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Protein kinase camp-dependent {ECO:0000313|EMBL:JAB55869.1};
DE Flags: Fragment;
OS Corethrella appendiculata.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Chaoboridae;
OC Corethrella.
OX NCBI_TaxID=1370023 {ECO:0000313|EMBL:JAB55869.1};
RN [1] {ECO:0000313|EMBL:JAB55869.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Salivary glands {ECO:0000313|EMBL:JAB55869.1};
RA Ribeiro J.M.C., Chagas A.C., Pham V.M., Lounibos L.P., Calvo E.;
RT "An insight into the sialome of the frog biting fly, Corethrella
RT appendiculata.";
RL Insect Biochem. Mol. Biol. 44:23-32(2014).
CC -!- FUNCTION: Extremely potent competitive inhibitor of cAMP-dependent
CC protein kinase activity, this protein interacts with the catalytic
CC subunit of the enzyme after the cAMP-induced dissociation of its
CC regulatory chains. {ECO:0000256|ARBA:ARBA00002844}.
CC -!- SIMILARITY: Belongs to the PKI family. {ECO:0000256|ARBA:ARBA00006393}.
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DR EMBL; GANO01004002; JAB55869.1; -; mRNA.
DR AlphaFoldDB; U5EF66; -.
DR GO; GO:0004862; F:cAMP-dependent protein kinase inhibitor activity; IEA:InterPro.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR InterPro; IPR004171; cAMP_dep_PKI.
DR PANTHER; PTHR15416:SF3; AGAP001779-PB; 1.
DR PANTHER; PTHR15416; CAMP-DEPENDENT PROTEIN KINASE INHIBITOR/PKI; 1.
DR Pfam; PF02827; PKI; 1.
PE 2: Evidence at transcript level;
KW Kinase {ECO:0000313|EMBL:JAB55869.1};
KW Transferase {ECO:0000313|EMBL:JAB55869.1}.
FT REGION 61..97
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:JAB55869.1"
SQ SEQUENCE 97 AA; 10386 MW; 9C0712841490315C CRC64;
IISIFAMDKV NTTTQPSQSD EFHSEFYNTG RIGRRNALPD ILGQHCTTTT ADLPNKLSAL
TTTDNSTNSV EPGTSGINNI NCTTTSNTTT NTSDSNT
//