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Database: UniProt
Entry: U5Q9G7_9BACT
LinkDB: U5Q9G7_9BACT
Original site: U5Q9G7_9BACT 
ID   U5Q9G7_9BACT            Unreviewed;       471 AA.
AC   U5Q9G7;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   05-JUL-2017, entry version 26.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:AGY54010.1};
GN   ORFNames=BRDCF_p1383 {ECO:0000313|EMBL:AGY54010.1};
OS   Bacteroidales bacterium CF.
OC   Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales.
OX   NCBI_TaxID=1400053 {ECO:0000313|EMBL:AGY54010.1, ECO:0000313|Proteomes:UP000017642};
RN   [1] {ECO:0000313|EMBL:AGY54010.1, ECO:0000313|Proteomes:UP000017642}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CF {ECO:0000313|EMBL:AGY54010.1};
RX   PubMed=24356833;
RA   Tang S., Edwards E.A.;
RT   "Complete Genome Sequence of Bacteroidales Strain CF from a
RT   Chloroform-Dechlorinating Enrichment Culture.";
RL   Genome Announc. 1:e01066-13(2013).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP006772; AGY54010.1; -; Genomic_DNA.
DR   RefSeq; WP_022546084.1; NZ_CP006772.1.
DR   KEGG; bacc:BRDCF_p1383; -.
DR   KO; K02313; -.
DR   Proteomes; UP000017642; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000017642};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017642}.
FT   DOMAIN      166    297       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      378    447       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     174    181       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   471 AA;  53541 MW;  2688F801AFA276A8 CRC64;
     MSEASYTTVW NNCLQIVKDN IPPQSFKTWF EPIKAVKLTG SILTIAVPTH FFIEFLEEYY
     IDLISKALKR ELGRDAKLEY NVKVISNEKP VQIPHQSTAE ITNKTLPFPN QARQIANPFV
     IPGLQQLKID PQLNPHFSFE NFIEGECNRL ARSAGLTIAS NPGSSAFNPL FLYGGSGLGK
     THLAQAIGIN IKERFPDKIV LYVSANRFQT QFMDAVNVKN KLTDFLHFYQ MIDVLIIDDV
     QEFAGKSGTQ NAFFHIFSHL HNLGKQLILT SDKPPVDLQD LEQRLLSRFK WGLLAELRQP
     DYQTRMAIIR AKCYNDGVTL PEEVVSYLAS RVTTNIREIE GTLNSLLAQA IFNNKTIDME
     LAESLTEKIV SRNRNELTID EIQKTVCEYF KINTELFLSS SRKRELVQAR QIAMFLSRNL
     TNNSLATIGS QTGGRDHATV LHAYNTVCDL IDTDRSFRKY VTDIEKKLKP Q
//
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