ID U5TJ92_COWPX Unreviewed; 785 AA.
AC U5TJ92;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Uncoating factor OPG117 {ECO:0000256|ARBA:ARBA00034867};
GN ORFNames=CPXV122 {ECO:0000313|EMBL:AGY99182.1};
OS Cowpox virus (CPV).
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus.
OX NCBI_TaxID=10243 {ECO:0000313|EMBL:AGZ00663.1, ECO:0000313|Proteomes:UP000125131};
OH NCBI_TaxID=10129; Apodemus sylvaticus (European woodmouse).
OH NCBI_TaxID=9913; Bos taurus (Bovine).
OH NCBI_TaxID=9685; Felis catus (Cat) (Felis silvestris catus).
OH NCBI_TaxID=9606; Homo sapiens (Human).
OH NCBI_TaxID=9785; Loxodonta africana (African elephant).
OH NCBI_TaxID=29092; Microtus agrestis (Short-tailed field vole).
OH NCBI_TaxID=10090; Mus musculus (Mouse).
OH NCBI_TaxID=447135; Myodes glareolus (Bank vole) (Clethrionomys glareolus).
RN [1] {ECO:0000313|Proteomes:UP000117858, ECO:0000313|Proteomes:UP000118701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HumAac09/1 {ECO:0000313|EMBL:AGZ00663.1}, HumGra07/1
RC {ECO:0000313|EMBL:AGZ01081.1}, HumKre08/1
RC {ECO:0000313|EMBL:AGZ01507.1}, RatAac09/1
RC {ECO:0000313|EMBL:AGY99182.1}, RatGer09/1
RC {ECO:0000313|EMBL:AGY99598.1}, and RatKre08/2
RC {ECO:0000313|EMBL:AGZ00028.1};
RA Dabrowski P.W., Radonic A., Kurth A., Nitsche A.;
RT "Genome-wide comparison of cowpoxviruses reveals a new clade related to
RT Variola virus.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CRL86590.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RatPox09 {ECO:0000313|EMBL:CRL86590.1};
RX PubMed=26311891; DOI=10.1128/JVI.01195-15;
RA Hoffmann D., Franke A., Jenckel M., Tamosiunaite A., Schluckebier J.,
RA Granzow H., Hoffmann B., Fischer S., Ulrich R.G., Hoper D., Goller K.,
RA Osterrieder N., Beer M.;
RT "Out of the reservoir: Phenotypic and genotypic characterization of a novel
RT cowpox virus isolated from a common vole.";
RL J. Virol. 0:0-0(2015).
RN [3] {ECO:0000313|EMBL:CRL86590.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=RatPox09 {ECO:0000313|EMBL:CRL86590.1};
RA Michener P.S., Gardner A.G., Jabaily R.S., Sessa E.;
RT "Utilizing next-generation sequencing to resolve the backbone and inform
RT taxonomy of the Core Goodeniaceae.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:AZY88962.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CPXV/Boa Marl {ECO:0000313|EMBL:AZY89325.1}, CPXV/Boy
RC Biederstein {ECO:0000313|EMBL:AZY88962.1}, CPXV/Cepad 332
RC {ECO:0000313|EMBL:AZY91356.1}, CPXV/Cepad 333
RC {ECO:0000313|EMBL:AZY90235.1}, CPXV/Compiegne 2009
RC {ECO:0000313|EMBL:AZY89688.1}, CPXV/Rat Biederstein
RC {ECO:0000313|EMBL:AZY89510.1}, CPXV/Rat Koelle
RC {ECO:0000313|EMBL:AZY90982.1}, and CPXV/Rat Marl
RC {ECO:0000313|EMBL:AZY89140.1};
RA Antwerpen M.H., Georgi E., Nikolic A., Wohlsein P., Baumgartner W.,
RA Zoeller G., Peyrefitte C., Charell R., Meyer H.;
RT "Use of NGS to study Cowpox virus outbreaks.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the orthopoxvirus OPG117 family.
CC {ECO:0000256|ARBA:ARBA00034752}.
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DR EMBL; KC813501; AGY99182.1; -; Genomic_DNA.
DR EMBL; KC813503; AGY99598.1; -; Genomic_DNA.
DR EMBL; KC813505; AGZ00028.1; -; Genomic_DNA.
DR EMBL; KC813508; AGZ00663.1; -; Genomic_DNA.
DR EMBL; KC813510; AGZ01081.1; -; Genomic_DNA.
DR EMBL; KC813512; AGZ01507.1; -; Genomic_DNA.
DR EMBL; MK035746; AZY88962.1; -; Genomic_DNA.
DR EMBL; MK035747; AZY89140.1; -; Genomic_DNA.
DR EMBL; MK035748; AZY89325.1; -; Genomic_DNA.
DR EMBL; MK035749; AZY89510.1; -; Genomic_DNA.
DR EMBL; MK035750; AZY89688.1; -; Genomic_DNA.
DR EMBL; MK035753; AZY90235.1; -; Genomic_DNA.
DR EMBL; MK035757; AZY90982.1; -; Genomic_DNA.
DR EMBL; MK035759; AZY91356.1; -; Genomic_DNA.
DR EMBL; LN864565; CRL86590.1; -; Genomic_DNA.
DR Proteomes; UP000117858; Genome.
DR Proteomes; UP000118701; Genome.
DR Proteomes; UP000125131; Genome.
DR Proteomes; UP000127103; Genome.
DR Proteomes; UP000145073; Genome.
DR Proteomes; UP000164362; Genome.
DR Proteomes; UP000166586; Genome.
DR Proteomes; UP000283857; Genome.
DR Proteomes; UP000284602; Genome.
DR Proteomes; UP000284816; Genome.
DR Proteomes; UP000285176; Genome.
DR Proteomes; UP000285555; Genome.
DR Proteomes; UP000286331; Genome.
DR Proteomes; UP000286356; Genome.
DR Proteomes; UP000286572; Genome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR004968; DNA_primase/NTPase_C.
DR InterPro; IPR014015; Helicase_SF3_DNA-vir.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014818; Phage/plasmid_primase_P4_C.
DR Pfam; PF08706; D5_N; 1.
DR Pfam; PF03288; Pox_D5; 1.
DR PROSITE; PS51206; SF3_HELICASE_1; 1.
PE 3: Inferred from homology;
FT DOMAIN 477..639
FT /note="SF3 helicase"
FT /evidence="ECO:0000259|PROSITE:PS51206"
SQ SEQUENCE 785 AA; 90402 MW; B6725A09FCB0873C CRC64;
MDATIRGNDI IFVLKTIGVP SACRQNEDPR FVEAFKCDEL ERYIENNPEC TLFESLRDEE
AYSIVRIFMD VDLDACLDEI DYLTAIQDFI IEVSNCVARF AFTECGAIHE NVIKSMRSNF
SLTKSTNRDK TSFHIIFLDT YTTMDTLIAM KRTLLELSRS SENPLTRSID TAVYRRKTTL
RVVGTRKNPN CDTIHVMQPP HDNIEDYLFT YVDMNNNSYY FSLQRRLEDL VPDKLWEPGF
ISFEDAIKRV SKIFINSIIN FNDLDENNFT TVPLVIDYVT PCALCKKRSH KHPHQLSLEN
GAIRIYKTGN PHSCKVKIVP LDGNKLFNIA QRILDTNSVL LTERGDHIVW INNSWKFNSE
EPLITKLILS IRHQLPKEYS SELLCPRKRK TVEANIRDML VDSVETDTYP DKLPFKNGVL
DLVDGMFYSG DDAKKYTCTV STGFKFDDTK FVEDSPEMEE LMNIINDIQP LTDENKKNRE
LYEKTLSSCL CGATKGCLTF FFGETATGKS TTKRLLKSAI GDLFVETGQT ILTDVLDKGP
NPFIANMHLK RSVFCSELPD FACSGSKKIR SDNIKKLTEP CVIGRPCFSN KINNRNHATI
IIDTNYKPVF DRIDNALMRR IAVVRFRTHF SQPSGREAAE NNDAYDKVKL LDEGLDGKIQ
NNRYRFAFLY LLVKWYKKYH VPIMKLYPTP EEIPDFAFYL KIGTLLVSSS VKHIPLMTDL
SKKGYILYDN VVTLPLTTFQ QKISKYFNSR LFGHDIESFI NRHKKFANVS DEYLQYIFIE
DISSP
//
