ID U5VPL9_9ACTN Unreviewed; 892 AA.
AC U5VPL9;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Putative diguanylate cyclase/phosphodiesterase with PAS sensor {ECO:0000313|EMBL:AGZ38749.1};
GN ORFNames=AFR_02300 {ECO:0000313|EMBL:AGZ38749.1};
OS Actinoplanes friuliensis DSM 7358.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=1246995 {ECO:0000313|EMBL:AGZ38749.1, ECO:0000313|Proteomes:UP000017746};
RN [1] {ECO:0000313|EMBL:AGZ38749.1, ECO:0000313|Proteomes:UP000017746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 7358 {ECO:0000313|EMBL:AGZ38749.1,
RC ECO:0000313|Proteomes:UP000017746};
RX PubMed=24637369; DOI=10.1016/j.jbiotec.2014.03.011;
RA Ruckert C., Szczepanowski R., Albersmeier A., Goesmann A., Fischer N.,
RA Steinkamper A., Puhler A., Biener R., Schwartz D., Kalinowski J.;
RT "Complete genome sequence of the actinobacterium Actinoplanes friuliensis
RT HAG 010964, producer of the lipopeptide antibiotic friulimycin.";
RL J. Biotechnol. 178:41-42(2014).
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DR EMBL; CP006272; AGZ38749.1; -; Genomic_DNA.
DR RefSeq; WP_023357692.1; NC_022657.1.
DR AlphaFoldDB; U5VPL9; -.
DR STRING; 1246995.AFR_02300; -.
DR KEGG; afs:AFR_02300; -.
DR PATRIC; fig|1246995.3.peg.465; -.
DR eggNOG; COG5001; Bacteria.
DR HOGENOM; CLU_000445_129_3_11; -.
DR OrthoDB; 3304401at2; -.
DR Proteomes; UP000017746; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF08447; PAS_3; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000017746};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 14..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 79..95
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 107..128
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 140..161
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 173..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 211..232
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 238..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 273..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..319
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 332..402
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 488..620
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 629..880
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 892 AA; 93982 MW; 004B625F223EF486 CRC64;
MDHAPRTSAW DRRLLLISGS LAVAGTVWFT VVYAFGEIGP TILGWAMMPV SAAVATVVCR
RSSTDPSLTD AARLFWRRFG FAFAVLTAAM TSHVIDSIGP GLAMSTRVGA VTGLLHAAFL
LLLSWPLFGL PLGARTRGQL VTTGLDVGIL VSGAAVFFWH FSAQRLFEGS AAGTVSIVAS
VSFVITGLVT MLAIAKVAAT GATSLGHRSM WALGSSLVAT GLVTALTPLL ATRPHLDITL
LGVPVAAFLV AFGAAGTRAH GLPPAPNRRR TSPLPYVMAA ATNALLIYVV AVDSSDRLPV
TVVAVLLTGL VIIRQLIALR DNDNLVTRLE HREERFRLLV QNSTDVVTIT APNGRIHYIS
PAVRRVLGSE PEPMAGTNIA HRVHPDDREV VATNVAHVIS RPGNSATYQA RMSHADGSWR
TLEIISVNLT DVPSVAGVVS NSRDVTETVQ AHERLSYEAT HDVLTGLANR ALFGDRVQAG
VANAGPGNTI SIVLIDLDDF KTVNDTLGHS VGDGLLVAVA DRMRASVRPT DIVARLGGDE
FAILFEGVGG DTVDRVLERI ADALAVPVEI DGHLLGVRAS FGVVDGQAGD DDAGDLLRRA
DIAMYEAKER GEGGYQRYRP GMEARGAERN RLTAALLAAL DQDELVLRYQ PVVTLPEGRL
TGVEALVRWQ HPERGLLGPG EFIPGAEETG LIVPLGRWVL REACRQATAW IDDLGDLAPG
TMSVNASARQ LQEPGFAAEV AAALRDSGLA AGRLTIEITE STAVGGGATQ DNLRGLRALG
VRLSLDDFGT GASTLSLLAN CPVDQIKLDR SFAPGPGPDA IAGAVLQLAR ALGVEAVAEG
VETPAQAAKL GDLGYVRAQG FHFARPMTPE DVGAGIRARQ VTELAGSFSA RP
//
