ID U5VSZ2_9ACTN Unreviewed; 694 AA.
AC U5VSZ2;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Membrane protein ydfJ {ECO:0000313|EMBL:AGZ38845.1};
GN ORFNames=AFR_02780 {ECO:0000313|EMBL:AGZ38845.1};
OS Actinoplanes friuliensis DSM 7358.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=1246995 {ECO:0000313|EMBL:AGZ38845.1, ECO:0000313|Proteomes:UP000017746};
RN [1] {ECO:0000313|EMBL:AGZ38845.1, ECO:0000313|Proteomes:UP000017746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 7358 {ECO:0000313|EMBL:AGZ38845.1,
RC ECO:0000313|Proteomes:UP000017746};
RX PubMed=24637369; DOI=10.1016/j.jbiotec.2014.03.011;
RA Ruckert C., Szczepanowski R., Albersmeier A., Goesmann A., Fischer N.,
RA Steinkamper A., Puhler A., Biener R., Schwartz D., Kalinowski J.;
RT "Complete genome sequence of the actinobacterium Actinoplanes friuliensis
RT HAG 010964, producer of the lipopeptide antibiotic friulimycin.";
RL J. Biotechnol. 178:41-42(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP006272; AGZ38845.1; -; Genomic_DNA.
DR AlphaFoldDB; U5VSZ2; -.
DR STRING; 1246995.AFR_02780; -.
DR KEGG; afs:AFR_02780; -.
DR PATRIC; fig|1246995.3.peg.558; -.
DR eggNOG; COG2409; Bacteria.
DR HOGENOM; CLU_005108_5_2_11; -.
DR Proteomes; UP000017746; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000017746};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 151..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 196..215
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 242..259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 265..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 315..343
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 486..504
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 511..534
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 554..575
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 596..618
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 630..655
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 50..328
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
FT DOMAIN 419..664
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..20
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 694 AA; 72620 MW; CD400E253C9AB684 CRC64;
MTILSGQIGT REASSSDQGH GESGRAEKIV EQAGFPVRPA GEMVLIQGAD RDKAVADVTK
TLTGREGVAG VADPLVSPDG NSTLVPFTMS GDPETAKDRV LPLLDAVADV QARHPGVLVA
EAGDASGSKL IGDALDEGLT RLSMLSIPVS LGILLVAFGA VVAAVLPVGL AVTAVVAAIG
LLAGASRFAP TVDETMHVML LVGLAVGVDY CLFYIRRERD ERRNGADPHR ALVIAAQTSG
RSIWISGLTV IVAMAGMFFT QDATFTSFAV GTILVVATAV LGSLTVLPAL LSALGDKVDA
IKIPGLYRRR NDGRVWNAIL RVVLAKPLIS TIVAVGVLAA LAYPMLDLRT KGESIEDVSP
NSAIVQTYVK IGEAFPSETV PAEVVVQAPT VRGPQFDAAL ADFRTAAKAS GQLLEPIDVR
VNPAGTVAVV SVGLVGNGSD RTSESAVDTL RGRVAPDAFG QVPGATVAVG GDTAGSMDFN
QRLDESLPWV FGFVLGLAFL LLLVSFRSVV VAITGVVLNL LSVAAAYGML VFVFQYGHFE
SFLQFKSGGG ITNWMPLFLF IILFGLSMDY HVFVLSRIRE GHDRGLPTRQ AVSQGIGSTA
GVITSAAVVM VAVFSLFATL PLTATKELGV GLAAAVLLDA TIIRAVLLPA VMALLGEKNW
YLPRWLNWLP TIAHEPPPAV TQEPATDREL IPTA
//
