ID U5W691_9ACTN Unreviewed; 885 AA.
AC U5W691;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=HTH luxR-type domain-containing protein {ECO:0000259|PROSITE:PS50043};
GN ORFNames=AFR_31895 {ECO:0000313|EMBL:AGZ44639.1};
OS Actinoplanes friuliensis DSM 7358.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=1246995 {ECO:0000313|EMBL:AGZ44639.1, ECO:0000313|Proteomes:UP000017746};
RN [1] {ECO:0000313|EMBL:AGZ44639.1, ECO:0000313|Proteomes:UP000017746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 7358 {ECO:0000313|EMBL:AGZ44639.1,
RC ECO:0000313|Proteomes:UP000017746};
RX PubMed=24637369; DOI=10.1016/j.jbiotec.2014.03.011;
RA Ruckert C., Szczepanowski R., Albersmeier A., Goesmann A., Fischer N.,
RA Steinkamper A., Puhler A., Biener R., Schwartz D., Kalinowski J.;
RT "Complete genome sequence of the actinobacterium Actinoplanes friuliensis
RT HAG 010964, producer of the lipopeptide antibiotic friulimycin.";
RL J. Biotechnol. 178:41-42(2014).
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DR EMBL; CP006272; AGZ44639.1; -; Genomic_DNA.
DR RefSeq; WP_023560972.1; NC_022657.1.
DR AlphaFoldDB; U5W691; -.
DR STRING; 1246995.AFR_31895; -.
DR KEGG; afs:AFR_31895; -.
DR PATRIC; fig|1246995.3.peg.6456; -.
DR eggNOG; COG0457; Bacteria.
DR eggNOG; COG2197; Bacteria.
DR HOGENOM; CLU_006850_2_0_11; -.
DR OrthoDB; 3543649at2; -.
DR Proteomes; UP000017746; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd06170; LuxR_C_like; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR PANTHER; PTHR16305:SF35; TRANSCRIPTIONAL ACTIVATOR DOMAIN; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF00196; GerE; 1.
DR PRINTS; PR00038; HTHLUXR.
DR SMART; SM00421; HTH_LUXR; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS00622; HTH_LUXR_1; 1.
DR PROSITE; PS50043; HTH_LUXR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000017746}.
FT DOMAIN 818..883
FT /note="HTH luxR-type"
FT /evidence="ECO:0000259|PROSITE:PS50043"
SQ SEQUENCE 885 AA; 94160 MW; 5C82CA8F2F3D941A CRC64;
MGLVGRVPEV VALDRLRAAA AAGEGGAALL VGEAGMGKTT VVEEAVARAT AAGATVATGR
AVPDEGAPAY WPWLRLIEDL PGLPPELLTA ATAAGESPAA ARFRVAQRTV RALRETGHLV
LVLEDLHWAD AGSLALLRLL SRELPGSRLL VIATARPPFP LDDVPGAEVL RLEPWEPAAV
GAYLGPAAHA SWTPVVHRLS GGNPLYVREL TRQLSREDRL RRPAGGVGVP TELRRLVGRR
TAQLGAACRD LLGGAAALGA EIDVAVLRAA APEPAAVDDL LTEALDAGVL TDDPWRPALL
RFAHDLVRQA RYDDLARAER IAWHHRLADA LADAGAAPAE IARHRVRCAV DAESRQAAVA
ACRAAAAAAL DFAEAIRWHD HTIDLADSPA DRLARALASY ADGRLDHAIA DCTAVQRAGV
PTLAVEAALV VRGVAGAHGP ALEVLCERAL ALAGRHPRVL AQYAYLLAER GDVRRAGEIS
AEAMTLAEES GDPDDVAAAV HARHQIVDPF DQPEVVLALA DRSCSLDRPD AELWGRTWRI
DMFLMRGDTT AVEQETARLS TLADRLGWPL ARWHLLRARA ARSLLAGRFT EAEQLALEAR
DLAVRTQDGA GAQLFYAFGG GLALHTGRSE QYLGRAAEWL TSLLTVPIAA AQLGRTAMDA
GDTTTVELCW QNLRPILAGL PPDGRRTYVL ITSGELAAWL GDLESARKCY DRTVRYEHIH
LNNTTSCYGA TARSLGTIAS ALGDHDAAVR HLTTAVTMDA SSPPFEAHAK LGLAQALISR
AAPGDRRRAQ DLATEAATAA RRLGMPPVAT AAQTLADKTS GAGALTTRER EIAHLVAEGH
PNRTIAADLV LSERTVETHV RNLLAKLGLT NRTQIATWIR TTSQR
//
