ID U5WB60_9ACTN Unreviewed; 253 AA.
AC U5WB60;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Metallophosphoesterase {ECO:0000313|EMBL:AGZ46227.1};
GN ORFNames=AFR_39865 {ECO:0000313|EMBL:AGZ46227.1};
OS Actinoplanes friuliensis DSM 7358.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=1246995 {ECO:0000313|EMBL:AGZ46227.1, ECO:0000313|Proteomes:UP000017746};
RN [1] {ECO:0000313|EMBL:AGZ46227.1, ECO:0000313|Proteomes:UP000017746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 7358 {ECO:0000313|EMBL:AGZ46227.1,
RC ECO:0000313|Proteomes:UP000017746};
RX PubMed=24637369; DOI=10.1016/j.jbiotec.2014.03.011;
RA Ruckert C., Szczepanowski R., Albersmeier A., Goesmann A., Fischer N.,
RA Steinkamper A., Puhler A., Biener R., Schwartz D., Kalinowski J.;
RT "Complete genome sequence of the actinobacterium Actinoplanes friuliensis
RT HAG 010964, producer of the lipopeptide antibiotic friulimycin.";
RL J. Biotechnol. 178:41-42(2014).
CC -!- SIMILARITY: Belongs to the cyclic nucleotide phosphodiesterase class-
CC III family. {ECO:0000256|ARBA:ARBA00025742}.
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DR EMBL; CP006272; AGZ46227.1; -; Genomic_DNA.
DR RefSeq; WP_023562560.1; NC_022657.1.
DR AlphaFoldDB; U5WB60; -.
DR STRING; 1246995.AFR_39865; -.
DR KEGG; afs:AFR_39865; -.
DR PATRIC; fig|1246995.3.peg.8066; -.
DR eggNOG; COG1409; Bacteria.
DR HOGENOM; CLU_070320_2_1_11; -.
DR OrthoDB; 5241795at2; -.
DR Proteomes; UP000017746; Chromosome.
DR GO; GO:0004115; F:3',5'-cyclic-AMP phosphodiesterase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd07402; MPP_GpdQ; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR026575; GpdQ/CpdA-like.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR PANTHER; PTHR42988:SF2; CYCLIC NUCLEOTIDE PHOSPHODIESTERASE CBUA0032-RELATED; 1.
DR PANTHER; PTHR42988; PHOSPHOHYDROLASE; 1.
DR Pfam; PF00149; Metallophos; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Reference proteome {ECO:0000313|Proteomes:UP000017746}.
FT DOMAIN 5..186
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
SQ SEQUENCE 253 AA; 27013 MW; 51FDB4BA3B16AC58 CRC64;
MTSFIAQLSD SHITTGPLSG GPAAGLQLAL ARVMALDPRP DCVVITGDLT DHGRPDEYAA
LREIIGSFPL PLHLTTGNHD DRVALLDVFG GEAYYLVEYP EFTVVALDSL IPGSPAGELG
AEQLAWLDQV LGRRPGMPVL IGLHHPPVPV GIRFLDNMRL RDGETLREVV SGHSNVVRVM
AGHVHRTITT GFAGSLLTIA PSLWRQAGLL FNSDEPPGYL AEPTGFLLHM IDGPDCVTHT
VPVSHTAALL GAY
//
