ID U5WIV2_MYCKA Unreviewed; 639 AA.
AC U5WIV2;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Multidrug ABC transporter ATP-binding protein {ECO:0000313|EMBL:AGZ48907.1};
GN ORFNames=MKAN_00310 {ECO:0000313|EMBL:AGZ48907.1};
OS Mycobacterium kansasii ATCC 12478.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=557599 {ECO:0000313|EMBL:AGZ48907.1, ECO:0000313|Proteomes:UP000017786};
RN [1] {ECO:0000313|EMBL:AGZ48907.1, ECO:0000313|Proteomes:UP000017786}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 12478 {ECO:0000313|EMBL:AGZ48907.1,
RC ECO:0000313|Proteomes:UP000017786};
RG McGill University Mycobacterium genome consortium;
RA Veyrier F.J., Behr M.A.;
RT "Genome sequence of Mycobacterium kansasii.";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP006835; AGZ48907.1; -; Genomic_DNA.
DR RefSeq; WP_023364036.1; NC_022663.1.
DR AlphaFoldDB; U5WIV2; -.
DR GeneID; 29700208; -.
DR KEGG; mkn:MKAN_00310; -.
DR eggNOG; COG4178; Bacteria.
DR HOGENOM; CLU_007587_6_2_11; -.
DR OrthoDB; 9810134at2; -.
DR Proteomes; UP000017786; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03223; ABCD_peroxisomal_ALDP; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11384:SF59; ATP-BINDING CASSETTE SUB-FAMILY D MEMBER; 1.
DR PANTHER; PTHR11384; ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER; 1.
DR Pfam; PF06472; ABC_membrane_2; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50929; ABC_TM1F; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:AGZ48907.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 20..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 65..86
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 121..141
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 214..235
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 255..277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 68..393
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 427..639
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 639 AA; 71839 MW; 8B20B5240CCABE2E CRC64;
MGPKPFTPSI DWSGAFVDSL YWIGKAWAIS AVCVLAVLVL LRFLTPWGRQ YWRITREYFV
GPRSIWVWLM LGVLLLSVVL AVRLNVLFSY QGNDMYTALQ KAFQGAAAGD EVVKRSGVQG
FWMSIGVFSI MAVIHVVRVM ADIYLTQRFI IAWRVWLTDH LTKDWLDGRA YYRDLFIDET
IDNPDQRIQQ DIDIFTAGVG GTPNAPSNGT GSTLLFGAVQ SIISVISFTA ILWNLSGTLN
IWGVSFPRAM FWTVLGYVLV ATVISFVIGR PLIWLSFRNE KLNAAFRYAL VRLRDAAEAV
GFYRGERVEG AQLQQRFRPV IDNYRRYVRR SIAFNGWNLS VSQTIVPLPW VIQAPRLFAG
QIEFGDVSQT AIAFGNIHDS LSFFRNNYDA FASFRAAIIR LYGLVDANEK GRALPAVLTR
PSDDESVELN EIEVRTPAGD RLIDPLDVRL DRGDSLVITG RSGSGKTSLL RSLAELWPYA
SGTLRRPDGD NETMFLSQLP YVPLGTLRDV VCYPNPPFVI PDDIVRDTLT KVALAPLCDR
LEEERDWAKV LSPGEQQRVA FARILLTKPK AVFLDESTSA LDAGLEFALY ELLRRELPDC
IIVSVSHRPA LERLHDQQLE LLGGGPWRLS PVTKEPVRV
//
