ID U5WUK0_MYCKA Unreviewed; 396 AA.
AC U5WUK0;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Crotonase {ECO:0000313|EMBL:AGZ52824.1};
GN ORFNames=MKAN_22885 {ECO:0000313|EMBL:AGZ52824.1};
OS Mycobacterium kansasii ATCC 12478.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=557599 {ECO:0000313|EMBL:AGZ52824.1, ECO:0000313|Proteomes:UP000017786};
RN [1] {ECO:0000313|EMBL:AGZ52824.1, ECO:0000313|Proteomes:UP000017786}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 12478 {ECO:0000313|EMBL:AGZ52824.1,
RC ECO:0000313|Proteomes:UP000017786};
RG McGill University Mycobacterium genome consortium;
RA Veyrier F.J., Behr M.A.;
RT "Genome sequence of Mycobacterium kansasii.";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the enoyl-CoA hydratase/isomerase family.
CC {ECO:0000256|ARBA:ARBA00005254}.
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DR EMBL; CP006835; AGZ52824.1; -; Genomic_DNA.
DR AlphaFoldDB; U5WUK0; -.
DR KEGG; mkn:MKAN_22885; -.
DR eggNOG; COG1024; Bacteria.
DR HOGENOM; CLU_696022_0_0_11; -.
DR Proteomes; UP000017786; Chromosome.
DR GO; GO:0016289; F:CoA hydrolase activity; IEA:UniProt.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
DR CDD; cd06558; crotonase-like; 1.
DR CDD; cd03443; PaaI_thioesterase; 1.
DR Gene3D; 3.10.129.10; Hotdog Thioesterase; 1.
DR Gene3D; 1.10.12.10; Lyase 2-enoyl-coa Hydratase, Chain A, domain 2; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR001753; Enoyl-CoA_hydra/iso.
DR InterPro; IPR014748; Enoyl-CoA_hydra_C.
DR InterPro; IPR029069; HotDog_dom_sf.
DR InterPro; IPR003736; PAAI_dom.
DR InterPro; IPR006683; Thioestr_dom.
DR NCBIfam; TIGR00369; unchar_dom_1; 1.
DR PANTHER; PTHR43802; ENOYL-COA HYDRATASE; 1.
DR PANTHER; PTHR43802:SF1; IP11341P-RELATED; 1.
DR Pfam; PF03061; 4HBT; 1.
DR Pfam; PF00378; ECH_1; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
DR SUPFAM; SSF54637; Thioesterase/thiol ester dehydrase-isomerase; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 311..385
FT /note="Thioesterase"
FT /evidence="ECO:0000259|Pfam:PF03061"
SQ SEQUENCE 396 AA; 42607 MW; 84F85C4B2654137B CRC64;
MQDVLRREVR NGVALLTLNR PDALNAYTPE IGRRLGEAYR RCDSDDSVRV IVVTGSGSAF
CAGADMSDAD PFDSPTHSDF SASPVQPAAF ELRKPVIAAM NGHAIGIGFT LALQADIRVA
AEEAKYGVVQ SRRGVIGDCM SHWTLLRLVG LATAADLLLT GRTVRGTEVA RMGIANAAVP
GTEVLKHAMT IATDIVENVA PMSAALSKRL LWDTAINGYA PQQVGELEIQ LHRRLMGRDD
SREAVAAYRA KRAPMWTASV PADWQDLPDR RVDAAMKHHF AELLGFRYGR SDQQQAVVEA
MPTAEHCNER GTVHGGFLAA LLDAATGLAV HSALDEQLTA PHFDLTIQYL RPAVPGTLLT
CVARTTKAGR RVVASEAEVF QDGKMVARAI GSHAVV
//
