ID   U5WV68_MYCKA            Unreviewed;       443 AA.
AC   U5WV68;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   SubName: Full=Hydrolase {ECO:0000313|EMBL:AGZ51816.1};
GN   ORFNames=MKAN_17140 {ECO:0000313|EMBL:AGZ51816.1};
OS   Mycobacterium kansasii ATCC 12478.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=557599 {ECO:0000313|EMBL:AGZ51816.1, ECO:0000313|Proteomes:UP000017786};
RN   [1] {ECO:0000313|EMBL:AGZ51816.1, ECO:0000313|Proteomes:UP000017786}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 12478 {ECO:0000313|EMBL:AGZ51816.1,
RC   ECO:0000313|Proteomes:UP000017786};
RG   McGill University Mycobacterium genome consortium;
RA   Veyrier F.J., Behr M.A.;
RT   "Genome sequence of Mycobacterium kansasii.";
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP006835; AGZ51816.1; -; Genomic_DNA.
DR   RefSeq; WP_023369937.1; NC_022663.1.
DR   AlphaFoldDB; U5WV68; -.
DR   GeneID; 29697083; -.
DR   KEGG; mkn:MKAN_17140; -.
DR   eggNOG; COG2114; Bacteria.
DR   eggNOG; COG2267; Bacteria.
DR   HOGENOM; CLU_036293_0_0_11; -.
DR   OrthoDB; 27092at2; -.
DR   Proteomes; UP000017786; Chromosome.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR000073; AB_hydrolase_1.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   PANTHER; PTHR43433:SF8; BLL8011 PROTEIN; 1.
DR   PANTHER; PTHR43433; HYDROLASE, ALPHA/BETA FOLD FAMILY PROTEIN; 1.
DR   Pfam; PF00561; Abhydrolase_1; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   PRINTS; PR00111; ABHYDROLASE.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:AGZ51816.1}.
FT   DOMAIN          289..396
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
SQ   SEQUENCE   443 AA;  47842 MW;  968D37DA40B2A372 CRC64;
     MTAPLRYARN GDVRLAYRVF GDTGPFLIWV SGWVLSNVDT IDEPGSPYAE FIDRVSQSTR
     LIVWDRRGTG LSDPSTQPLS LDQRIDDVRA ILDAAGAGRA AFLGTSEGGS VSVLFAATHP
     ERVASLVLYG TAARYSQELP DFPWGFTPAE IESQLDEIDD RWGEGALADL FYSATADTSG
     VRAMFGKLQR AIASPTMAKL WWKAFMEIDV RSVLGLVRAP TLVFARPGDR LVPIEAAAAL
     AAAIPEAHFQ PLPPGPHSPF DIIADFVPSV VEFVCEKPSE RPDERILKAV MFTDIVGSTE
     QLSATGDAHW RHQLDAHDRA VDWLLAKYGG HRAKHTGDGI FALFDGPTKA VRCALDLVPT
     LATRGIQIRA GVHVGECERR GEEWSGMAVH TGARVGALAG AGEVVASRTV RDLSAGSGLS
     FESLGPQRLK GLPEAVEVYR VTT
//