ID U5X0C0_MYCKA Unreviewed; 335 AA.
AC U5X0C0;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=UPF0353 protein MKAN_27220 {ECO:0000256|HAMAP-Rule:MF_01340};
GN ORFNames=MKAN_27220 {ECO:0000313|EMBL:AGZ53581.1};
OS Mycobacterium kansasii ATCC 12478.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=557599 {ECO:0000313|EMBL:AGZ53581.1, ECO:0000313|Proteomes:UP000017786};
RN [1] {ECO:0000313|EMBL:AGZ53581.1, ECO:0000313|Proteomes:UP000017786}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 12478 {ECO:0000313|EMBL:AGZ53581.1,
RC ECO:0000313|Proteomes:UP000017786};
RG McGill University Mycobacterium genome consortium;
RA Veyrier F.J., Behr M.A.;
RT "Genome sequence of Mycobacterium kansasii.";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|HAMAP-Rule:MF_01340};
CC Multi-pass membrane protein {ECO:0000256|HAMAP-Rule:MF_01340}.
CC -!- SIMILARITY: Belongs to the UPF0353 family. {ECO:0000256|HAMAP-
CC Rule:MF_01340}.
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DR EMBL; CP006835; AGZ53581.1; -; Genomic_DNA.
DR RefSeq; WP_023373363.1; NC_022663.1.
DR AlphaFoldDB; U5X0C0; -.
DR GeneID; 29699337; -.
DR KEGG; mkn:MKAN_27220; -.
DR eggNOG; COG2304; Bacteria.
DR HOGENOM; CLU_024570_2_0_11; -.
DR OrthoDB; 8882959at2; -.
DR Proteomes; UP000017786; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR CDD; cd00198; vWFA; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR HAMAP; MF_01340; UPF0353; 1.
DR InterPro; IPR024163; Aerotolerance_reg_N.
DR InterPro; IPR022933; UPF0353.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR22550; SPORE GERMINATION PROTEIN; 1.
DR PANTHER; PTHR22550:SF19; UPF0353 PROTEIN RV1481; 1.
DR Pfam; PF07584; BatA; 1.
DR Pfam; PF13519; VWA_2; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|HAMAP-Rule:MF_01340};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_01340};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP-
KW Rule:MF_01340};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|HAMAP-
KW Rule:MF_01340}.
FT TRANSMEM 16..36
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01340"
FT TRANSMEM 67..85
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01340"
FT TRANSMEM 310..329
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01340"
FT DOMAIN 98..294
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
SQ SEQUENCE 335 AA; 35845 MW; 4B62359DBE751EF0 CRC64;
MTLPLLGPMT LSGFEHSWFF LFLFVIVGLV ALYIVLQLAR QKRMLRFANM ELLESVAPKR
PSRWRHVPAI LLALSLVLLT TAMAGPTHDV RIPRNRAVVM LVIDVSQSMR ATDVEPNRMV
AAQEAAKQFA DELTPGINLG LIAYAGTATV LVSPTTNRDA TKNALDKLQF ADRTATGEAI
FTALQAIATV GAVIGGGDTP PPARIVLFSD GKETMPTNPD NPKGAFTAAR TAKDQGVPIS
TISFGTPYGF VEINGQRQPV PVDDETLKKV AQLSGGNAYN AATLAELKSV YASLQQQIGY
ETIKGDASAG WLRLGALVLA LAGLAALLIN RRLPT
//
