ID U6CQD2_NEOVI Unreviewed; 886 AA.
AC U6CQD2;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Metabotropic glutamate receptor 7 {ECO:0000313|EMBL:CCP72711.1};
GN Name=GRM7 {ECO:0000313|EMBL:CCP72711.1};
OS Neovison vison (American mink) (Mustela vison).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Neogale.
OX NCBI_TaxID=452646 {ECO:0000313|EMBL:CCP72711.1};
RN [1] {ECO:0000313|EMBL:CCP72711.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Pool of brain {ECO:0000313|EMBL:CCP72711.1};
RA Anistoroaei R., Christensen K.;
RT "An American mink transcriptome.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 3 family.
CC {ECO:0000256|ARBA:ARBA00007242}.
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DR EMBL; HAAF01000885; CCP72711.1; -; mRNA.
DR AlphaFoldDB; U6CQD2; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR CDD; cd15451; 7tmC_mGluR7; 1.
DR CDD; cd06376; PBP1_mGluR_groupIII; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR017979; GPCR_3_CS.
DR InterPro; IPR001883; GPCR_3_mGluR7.
DR InterPro; IPR000162; GPCR_3_mtglu_rcpt.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR24060; METABOTROPIC GLUTAMATE RECEPTOR; 1.
DR PANTHER; PTHR24060:SF98; METABOTROPIC GLUTAMATE RECEPTOR 7; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF07562; NCD3G; 1.
DR PRINTS; PR00248; GPCRMGR.
DR PRINTS; PR01057; MTABOTROPC7R.
DR PRINTS; PR00593; MTABOTROPICR.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00979; G_PROTEIN_RECEP_F3_1; 1.
DR PROSITE; PS00980; G_PROTEIN_RECEP_F3_2; 1.
DR PROSITE; PS00981; G_PROTEIN_RECEP_F3_3; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 2: Evidence at transcript level;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:CCP72711.1};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 554..580
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 592..612
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 624..645
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 718..739
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 751..773
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 793..815
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 554..828
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
SQ SEQUENCE 886 AA; 99126 MW; 8B79B3FB4724B8CA CRC64;
MYAPHSIRIE GDVTLGGLFP VHAKGPSGVP CGDIKRENGI HRLEAMLYAL DQINSDPNLL
PNVTLGARIL DTCSRDTYAL EQSLTFVQAL IQKDTSDVRC TNGEPPVFVK PEKVVGVIGA
SGSSVSIMVA NILRLFQIPQ ISYASTAPEL SDDRRYDFFS RVVPPDSFQA QAMVDIVKAL
GWNYVSTLAS EGSYGEKGVE SFTQISKEAG GLCIAQSVRI PQERKDRTID FDRIIKQLLD
TPNSRAVVIF ANDEDIKQIL AAAKRADQVG HFLWVGSDSW GSKINPLHQH EDIAEGAITI
QPKRATVEGF DAYFTSRTLE NNRRNVWFAE YWEENFNCKL TISGSKKEDT DRKCTGQERI
GKDSNYEQEG KVQFVIDAVY AMAHALHHMN KDLCADYRGV CPEMEQAGGK KLLKYIRNVN
FNGSAGTPVM FNKNGDAPGR YDIFQYQTTN TTNPGYRLIG QWTDELQLNI EDMQWGKGVR
EIPPSVCTLP CKPGQRKKTQ KGTPCCWTCE PCDGYQYQFD EMTCQHCPYD QRPNENRTGC
QDIPIIKLEW HSPWAVIPVF LAMLGIIATI FVMATFIRYN DTPIVRASGR ELSYVLLTGI
FLCYIITFLM IAKPDVAVCS FRRVFLGLGM CISYAALLTK TNRIYRIFEQ GKKSVTAPRL
ISPTSQLAIT SSLISVQLLG VFIWFGVDPP NIIIDYDEHK TMNPEQARGV LKCDITDLQI
ICSLGYSILL MVTCTVYAIK TRGVPENFNE AKPIGFTMYT TCIVWLAFIP IFFGTAQSAE
KLYIQTTTLT ISMNLSASVA LGMLYMPKVY IIIFHPELNV QKRKRSFKAV VTAATMSSRL
SHKPSDRPNG EAKTELCENV DPNNCIPPVR KSVQKSVTWY TIPPTV
//
