ID   U6D6E2_NEOVI            Unreviewed;       721 AA.
AC   U6D6E2;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=Dynein heavy chain 2, axonemal {ECO:0000313|EMBL:CCP78550.1};
DE   Flags: Fragment;
GN   Name=DYH2 {ECO:0000313|EMBL:CCP78550.1};
OS   Neovison vison (American mink) (Mustela vison).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC   Mustelinae; Neogale.
OX   NCBI_TaxID=452646 {ECO:0000313|EMBL:CCP78550.1};
RN   [1] {ECO:0000313|EMBL:CCP78550.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Pool of brain {ECO:0000313|EMBL:CCP78550.1};
RA   Anistoroaei R., Christensen K.;
RT   "An American mink transcriptome.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; HAAF01006726; CCP78550.1; -; mRNA.
DR   AlphaFoldDB; U6D6E2; -.
DR   GO; GO:0030286; C:dynein complex; IEA:InterPro.
DR   GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR   GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR   GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   Gene3D; 1.20.1270.280; -; 1.
DR   Gene3D; 3.10.490.20; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.10.8.720; Region D6 of dynein motor; 1.
DR   InterPro; IPR041658; AAA_lid_11.
DR   InterPro; IPR042219; AAA_lid_11_sf.
DR   InterPro; IPR026983; DHC_fam.
DR   InterPro; IPR041228; Dynein_C.
DR   InterPro; IPR043160; Dynein_C_barrel.
DR   InterPro; IPR004273; Dynein_heavy_D6_P-loop.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR45703; DYNEIN HEAVY CHAIN; 1.
DR   PANTHER; PTHR45703:SF32; DYNEINS HEAVY CHAIN; 1.
DR   Pfam; PF18198; AAA_lid_11; 1.
DR   Pfam; PF18199; Dynein_C; 1.
DR   Pfam; PF03028; Dynein_heavy; 1.
PE   2: Evidence at transcript level;
FT   DOMAIN          127..240
FT                   /note="Dynein heavy chain region D6 P-loop"
FT                   /evidence="ECO:0000259|Pfam:PF03028"
FT   DOMAIN          272..411
FT                   /note="Dynein heavy chain AAA lid"
FT                   /evidence="ECO:0000259|Pfam:PF18198"
FT   DOMAIN          418..717
FT                   /note="Dynein heavy chain C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF18199"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:CCP78550.1"
SQ   SEQUENCE   721 AA;  81765 MW;  00931340350CB9E6 CRC64;
     SLALCPAQVL DREGQMDNPC TSWLADAYWD NITELDKLTN FHGLMNSFEQ YPRDWHLWYT
     NATPEKAMLP GEWENACNEM QRMLIVRSLR QDRVAFCVTS FIVSNLGSRF VEPPVLNMKL
     VMEDSSPRTP LVFILSPGVD PTSALLQLAE HTGMAQRFHA LSLGQGQAPI AARLLREGVS
     QGHWVFLANC HLSLSWMPNL DKLVEQLQVA EPHPSFRLWL SSSPHPDFPI SILQASIKMT
     TEPPKGLKAN MTRLYQLMTE AQFSRCAKPA KYKKLLFALC FFHSVLLERK KFLQLGWNII
     YGFNDSDFEV SENLLSLYLD EYDETPWDAL KYLIAGVNYG GHVTDDWDRR LLTTYINDYF
     CDQALSTPFH RLSVLEAYFI PKDGSLASYK EYISMLPGMD PPEAFGQHPN ADVASQITEA
     RTLFETLLSL QPQITPARAG SQSREEKVLE LAADVKQKIP EMIDYEGTRK LLAMDPSPLN
     VVLLQEIQRY NKLMETILSS LTDLEKGIQG LIVMSTSLEE IFNCIFDAHV PPLWGKAYPS
     QKPLASWTRD LATRVEQFEL WASRARPPVI FWLSGFTFPT GFLTAVLQSS ARQNNIPVDN
     LSWEFIVSTV DDSNLVYPPK DGVWVRGLYL EGAGWDRKNS CLVEAEPMQL VCPMPTIHFR
     PTESRKKSAK GMYSCPCYYY PNRAGSSDRS SFVIGIDLRS GTMTSDHWIK RGTALLMSLD
     N
//