ID   U6DDA1_NEOVI            Unreviewed;       742 AA.
AC   U6DDA1;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   SubName: Full=Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32 {ECO:0000313|EMBL:CCP80925.1};
DE   Flags: Fragment;
GN   Name=DHX32 {ECO:0000313|EMBL:CCP80925.1};
OS   Neovison vison (American mink) (Mustela vison).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC   Mustelinae; Neogale.
OX   NCBI_TaxID=452646 {ECO:0000313|EMBL:CCP80925.1};
RN   [1] {ECO:0000313|EMBL:CCP80925.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Pool of brain {ECO:0000313|EMBL:CCP80925.1};
RA   Anistoroaei R., Christensen K.;
RT   "An American mink transcriptome.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; HAAF01009101; CCP80925.1; -; mRNA.
DR   AlphaFoldDB; U6DDA1; -.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   CDD; cd17977; DEXHc_DHX32; 1.
DR   CDD; cd18791; SF2_C_RHA; 1.
DR   Gene3D; 1.20.120.1080; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR   InterPro; IPR048333; HA2_WH.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR   PANTHER; PTHR18934:SF88; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX32-RELATED; 1.
DR   Pfam; PF21010; HA2_C; 1.
DR   Pfam; PF04408; HA2_N; 1.
DR   Pfam; PF07717; OB_NTP_bind; 1.
DR   SMART; SM00847; HA2; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:CCP80925.1};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:CCP80925.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:CCP80925.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022806,
KW   ECO:0000313|EMBL:CCP80925.1}.
FT   DOMAIN          72..238
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        8..23
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         742
FT                   /evidence="ECO:0000313|EMBL:CCP80925.1"
SQ   SEQUENCE   742 AA;  83785 MW;  BCD04D388E07D472 CRC64;
     MEEADLECPD SASEKRYFPE SLDSSDGDEE GILACEDLEL NPFDGLPYSS RYYKLLKERE
     DLPIWKEKYS FMENLLQNQI VIVSGDAKCG KSSQVPQWCA EYCLSIHYQH GGVVCTQVHK
     PTAVQLALRV ADEMDVNIGH EVGYVIPFEN CCTSETILRY CTDDMLQREM MSSPFLGSYG
     VIILDDVHER SIATDVLLGL LKDVLLARPE LKLIINSSPH LVSKLSSYYG NVPLVEVRKQ
     HPVEVVHLSG AQKESFESIL RLIFEIHQSG EKGDIVVFLA CEQDIEKAYE IVCQEGSNLN
     PDLGELVVIP LYPKEKCALF KPNDETEKRC QVYQRRVVLT ASSGESLIWS NTVKFVIDVG
     VERRKVYNPR IRADSLVTQP ISRSQADTRK QLLGSSSSGK LFCLYSEEFA SKDMRPLKPA
     EMQEANLTSM VLFLKRIDIA GLGHCDFMNR PAPESLMQAL EDLDYLAALD NDGNLSEFGI
     IMSEFPLDPQ LSKSILASCE FDCVEEMLTI AAMVTAPNCF SNVPHGAEEA ALTRWKTFLH
     PEGDHFTLIN IYKAYQDTAL NSTSEHCVEK WCHDYFLNCC ALRMADVIRA ELLEIVKRIE
     LPCAEPAFGS KENALNIKKA LLSGYFMQIA RDVDGSGNYL MLTHKQVAQL HPLSSYSVTK
     KLPEWVLFHK FSIAENNYIR ITSEISPELF MQLAPPYYFS NLPPSESKDI LHQVMDHLSP
     LSTMKKDQKM CEKCPETTEP RC
//