ID U6DGH6_NEOVI Unreviewed; 493 AA.
AC U6DGH6;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=EPH receptor B1 {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN Name=C9JCC7 {ECO:0000313|EMBL:CCP81679.1};
OS Neovison vison (American mink) (Mustela vison).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Neogale.
OX NCBI_TaxID=452646 {ECO:0000313|EMBL:CCP81679.1};
RN [1] {ECO:0000313|EMBL:CCP81679.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Pool of brain {ECO:0000313|EMBL:CCP81679.1};
RA Anistoroaei R., Christensen K.;
RT "An American mink transcriptome.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251};
CC Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
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DR EMBL; HAAF01009855; CCP81679.1; -; mRNA.
DR AlphaFoldDB; U6DGH6; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0005003; F:ephrin receptor activity; IEA:InterPro.
DR CDD; cd00063; FN3; 2.
DR Gene3D; 2.60.40.1770; ephrin a2 ectodomain; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 1.
DR InterPro; IPR027936; Eph_TM.
DR InterPro; IPR001090; Ephrin_rcpt_lig-bd_dom.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR001426; Tyr_kinase_rcpt_V_CS.
DR PANTHER; PTHR46877; EPH RECEPTOR A5; 1.
DR PANTHER; PTHR46877:SF17; EPHRIN TYPE-B RECEPTOR 1; 1.
DR Pfam; PF14575; EphA2_TM; 1.
DR Pfam; PF01404; Ephrin_lbd; 1.
DR Pfam; PF00041; fn3; 2.
DR PRINTS; PR00014; FNTYPEIII.
DR SMART; SM00615; EPH_lbd; 1.
DR SMART; SM01411; Ephrin_rec_like; 1.
DR SMART; SM00060; FN3; 2.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR PROSITE; PS51550; EPH_LBD; 1.
DR PROSITE; PS50853; FN3; 2.
DR PROSITE; PS00790; RECEPTOR_TYR_KIN_V_1; 1.
DR PROSITE; PS00791; RECEPTOR_TYR_KIN_V_2; 1.
PE 2: Evidence at transcript level;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 435..457
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..95
FT /note="Eph LBD"
FT /evidence="ECO:0000259|PROSITE:PS51550"
FT DOMAIN 216..326
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 327..422
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:CCP81679.1"
FT NON_TER 493
FT /evidence="ECO:0000313|EMBL:CCP81679.1"
SQ SEQUENCE 493 AA; 54500 MW; 1FCDCD1CB954B4DF CRC64;
KETFNLYYYE TDSVIATKKS AFWSEAPYLK VDTIAADESF SQVDFGGRLM KVNTEVRSFG
PLTRNGFYLA FQDYGACMSL LSVRVFFKKC PSIVQNFAVF PETMTGAEST SLVIARGTCI
PNAEEVDVPI KLYCNGDGEW MGPLGRCTCK PGYEAENSVA CKACPAGMFK ASQEAEGCSH
CPSNSRSPSE ASPICTCRTG YYRADFDPPE VACTSVPSGP RNVISIVNET SIILEWHPPR
ETGGRDDVTY NIICRKCRAD RRSCSRCDDN VEFVPRQLGL TECRVSISSL WAHTPYTFDI
QAVNGVSSKS PFPPQHVSVN ITTNQAAPST VPIMHQVSAT MRSITLSWPQ PEQPNGIILD
YEIRYYEKEH NEFNSSMARS QTNTARIDGL RPGMVYVVQV RARTVAGYGK FSGKMCFQTL
TDDDYKSELR EQLPLIAGSA AAGVVFVVSL VAISIVCSRK RAYSKEAVYS DKLQHYSTGR
GSPGMKIYID PFT
//
