ID U6EAC3_9EURY Unreviewed; 786 AA.
AC U6EAC3;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=Signal transduction histidine kinase {ECO:0008006|Google:ProtNLM};
GN ORFNames=MBMB1_0843 {ECO:0000313|EMBL:CDG64946.1};
OS Methanobacterium sp. MB1.
OC Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC Methanobacteriales; Methanobacteriaceae; Methanobacterium.
OX NCBI_TaxID=1379702 {ECO:0000313|EMBL:CDG64946.1, ECO:0000313|Proteomes:UP000017867};
RN [1] {ECO:0000313|EMBL:CDG64946.1, ECO:0000313|Proteomes:UP000017867}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MB1 {ECO:0000313|Proteomes:UP000017867};
RA Maus I., Wibberg D., Stantscheff R., Cibis K., Eikmeyer F.G., Puehler A.,
RA Koenig H., Schlueter A.;
RT "Methanobacterium sp. Mb1.";
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; HG425166; CDG64946.1; -; Genomic_DNA.
DR AlphaFoldDB; U6EAC3; -.
DR STRING; 1379702.MBMB1_0843; -.
DR KEGG; meth:MBMB1_0843; -.
DR PATRIC; fig|1379702.4.peg.836; -.
DR HOGENOM; CLU_356686_0_0_2; -.
DR BioCyc; MSP1379702:MBMB1_RS04055-MONOMER; -.
DR Proteomes; UP000017867; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR011495; Sig_transdc_His_kin_sub2_dim/P.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR PANTHER; PTHR43065:SF23; SENSOR HISTIDINE KINASE PDTAS-RELATED; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07568; HisKA_2; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF08447; PAS_3; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000017867};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 39..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 69..92
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 147..165
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 172..192
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 204..225
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 246..263
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 275..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 316..369
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 441..512
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 575..781
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 786 AA; 89391 MW; CF0EB82597FAA27E CRC64;
MDQNTRDGLE PFKIPQDEDI KQSSAYLNRV RRFKLYSKIF AIIVILLGVM GVLGWFFDIP
LLRGEYGGVI GIKLNTTLLL ILSGSSVYLL NLKLKGNQIL IPRILGVIIV LVGLVTSIEY
IVGINLGMNY LFPGILTDNP ILSRSRLVSS VIFILIGSAI IMTSYKYKIR YVQSIAFFCG
FLAFFGLSSH LYGSSSSYLL DMMAQMAFMT SIAHICLSIG ILCLCPDHSY IGRITTENSG
GYMARHLLPF ALLAVFLMDL LIISGERFNI YSPSFGNVFG VILALSFLTT VIVWGAKMLN
KMDRQRQEAN LHSLNLKRFY ENLVEGINEG IWVTDKQDHL YFMNRGMEEI SGITSQEMEN
RDLLEDLFHT TEGLKEYYLE AKETLKPVHY DSIKSTSHRG HPTYQSGWII PQVKEGKFNG
AICTVIDETP RKEAENALKK SEAFYRTIFE NTGTATIIIG QDNTIIMANK RCESLVGYKV
AEIEHQLKWT NFVHPDDREK MKTYHHMRIS GKEAPSEYEF RLVNKNGDER EVLLFTSLIP
NTKNSVVSLL DITERNKAEN LIKKSLKDKE LLLREIHHRV KNNMQIISSL LNLQRNYVED
EETHNILHES QGRVKSMALI HEKLYQTPDL AKINIKNYLE SLTMNLFHSY RTNPNIKLNL
DVGDIYFNID TAIPLGLIIN ELVSNCLKYA FKDQDDGEIF ISLHKVDTDE LGEVNEENGA
EESYLLKVGD DGVGLPEDLH IEHTPTLGLQ LVNTLVSQVD GNLKITRNNG TCFQILFKEQ
KYTNRI
//
