ID   U6G3P2_9EIME            Unreviewed;      1284 AA.
AC   U6G3P2;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   SubName: Full=EF hand family protein, related {ECO:0000313|EMBL:CDI74841.1};
GN   ORFNames=EPH_0016690 {ECO:0000313|EMBL:CDI74841.1};
OS   Eimeria praecox.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC   Eucoccidiorida; Eimeriorina; Eimeriidae; Eimeria.
OX   NCBI_TaxID=51316 {ECO:0000313|EMBL:CDI74841.1};
RN   [1] {ECO:0000313|EMBL:CDI74841.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Houghton {ECO:0000313|EMBL:CDI74841.1};
RA   Reid A.J., Blake D., Billington K., Browne H., Dunn M., Hung S.,
RA   Kawahara F., Miranda-Saavedra D., Mourier T., Nagra H., Otto T.D.,
RA   Rawlings N., Sanchez A., Sanders M., Subramaniam C., Tay Y., Dear P.,
RA   Doerig C., Gruber A., Parkinson J., Shirley M., Wan K.L., Berriman M.,
RA   Tomley F., Pain A.;
RT   "Genomic analysis of the causative agents of coccidiosis in chickens.";
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CDI74841.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Houghton {ECO:0000313|EMBL:CDI74841.1};
RA   Aslett M.;
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; HG690568; CDI74841.1; -; Genomic_DNA.
DR   EnsemblProtists; CDI74841; CDI74841; EPH_0016690.
DR   VEuPathDB; ToxoDB:EPH_0016690; -.
DR   OrthoDB; 198501at2759; -.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0007338; P:single fertilization; IEA:UniProtKB-KW.
DR   CDD; cd00051; EFh; 2.
DR   Gene3D; 1.10.238.10; EF-hand; 3.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR018928; HAP2/GCS1_dom.
DR   InterPro; IPR001751; S100/CaBP7/8-like_CS.
DR   PANTHER; PTHR34524; CALCYPHOSIN; 1.
DR   PANTHER; PTHR34524:SF6; CALCYPHOSINE-LIKE-RELATED; 1.
DR   Pfam; PF13202; EF-hand_5; 1.
DR   Pfam; PF13499; EF-hand_7; 2.
DR   Pfam; PF10699; HAP2-GCS1; 1.
DR   SMART; SM00054; EFh; 4.
DR   SUPFAM; SSF47473; EF-hand; 2.
DR   PROSITE; PS00018; EF_HAND_1; 2.
DR   PROSITE; PS50222; EF_HAND_2; 4.
DR   PROSITE; PS00303; S100_CABP; 1.
PE   4: Predicted;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837};
KW   Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          764..799
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   DOMAIN          906..941
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   DOMAIN          1202..1237
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   DOMAIN          1238..1273
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   REGION          615..710
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        624..640
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        641..684
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        693..709
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1284 AA;  141894 MW;  9B7301874490722B CRC64;
     MSSAVSQKLQ FQWEAGDINE RSPRKSDAGN AGVVVTVQKT AVSYSYGLTY IKAVPYNWVE
     YAHRALLWQV KKGGETFCSD TWGSKWLRFG KIPDPYLTKF CPVVEYPWYR MLKVSENRTW
     FFKVHVGISW WRPPSPSSLS DEEYKAECSK KISEGSYPKN FDCSQRLHTE AGMADAILEL
     SDATKVARDT TFDVTARLIS SDMPDAPEGC SDSDDLAAWG VSETDNPDLA RLCKSGSTPC
     SPFCNPKSCL RHMIVLDEKD VTVDGATCDL PGVSLQQWGR DGFCDYSPGS CFAKNLKWFQ
     AYNEEVAKTG RTPPYALEYP PGNYPRYHAG LENANEAIDT SKAGPFELHR LAFAYPESHK
     SKVRIEMNAG LIRWIQSSAP GQITSIAPPA PRECDNAQTF GCPLKVYVLN SGSVDATFYL
     ELPYCTEHGS DEPTDKLDPV SAVQRNVPAG SSQAFDLTLR LTAVVQEFDF NCVMKLYDSE
     LNQLDIKSFD LLTGKAAVSL EPDLPTAVTN PTGEVTVVEP PEDKRNWFQR LMNVVPNDGE
     CDCSFWNVIC LPADWNDCFG SLKKALKIIL LAGITLVALF LLWPVLKPLL KIVCKCASIP
     FKCLRSAGRH RKTLRKAKKL RKKEAKKLEK EQRRMQQKAL EASQRRGSGS YSEEPDESQS
     SAAQGSESAV SSEVASSEAY ATEGRRQASN EEFTDADNSS STNDDGSKTH YNAQRTKVEE
     LRAALAHRPA FAAHKAFAAL DPLGNGCLTS GDLQRYLRNH GIAVTDSEAY NLLRRLDANG
     DGRVSFPEFV DFLLPAEPSE GELLLSRDQR SPQLPSRSAV ACYCCCCCCA DKKECACICS
     GGDACVAQLL HREVDAHRAL EVRRRILAAC PDFMLLAAFQ FLEEPSMAAI TPLSLQEALA
     EEGFALTHME QKLIFRRFDR DGDGRLKYLE FVEAVMPSNY PSSRSCSDPL ASGPHLCVCS
     LEASPIDCCS HSAAFSGSTR LTRRPKCSML RSSSSNSSLL RRPVLQPRKG CSCSASLRSF
     WNRSSSSTES DDSLLLSGTS STKRNSRFVA SECEVAGVLN SQIDTERRLE CLREKLALKS
     DFNLLQFWGL FDTEGRGYAT AVHIQDAFNA VGLNISLTQA RLFAGKLNSD SEPRLRYADM
     AKAFLPTKAR YAEAMINRTS NGSHKCSAPL THLAPETLDI VAAIFDLTLA SEEQAELSRH
     RLCLKDLSAA FRDLDKNGDG YITAAEFSAS LMAHGFRPSE AELNALVNRY DKNGDSKVSY
     AEFVNEIGRT RCPVGCCRLI CLCR
//