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Database: UniProt
Entry: U6GK46_EIMAC
LinkDB: U6GK46_EIMAC
Original site: U6GK46_EIMAC 
ID   U6GK46_EIMAC            Unreviewed;       992 AA.
AC   U6GK46;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   25-OCT-2017, entry version 17.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
GN   ORFNames=EAH_00047830 {ECO:0000313|EMBL:CDI79967.1};
OS   Eimeria acervulina (Coccidian parasite).
OC   Eukaryota; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC   Eucoccidiorida; Eimeriorina; Eimeriidae; Eimeria.
OX   NCBI_TaxID=5801 {ECO:0000313|EMBL:CDI79967.1, ECO:0000313|Proteomes:UP000018050};
RN   [1] {ECO:0000313|EMBL:CDI79967.1, ECO:0000313|Proteomes:UP000018050}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Houghton {ECO:0000313|EMBL:CDI79967.1};
RA   Aslett M.;
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-
CC       ATPase), a multimeric enzyme that catalyzes the translocation of
CC       protons across the membranes. Required for assembly and activity
CC       of the V-ATPase. {ECO:0000256|RuleBase:RU361189}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|RuleBase:RU361189}.
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DR   EMBL; HG671117; CDI79967.1; -; Genomic_DNA.
DR   RefSeq; XP_013250004.1; XM_013394550.1.
DR   EnsemblProtists; CDI79967; CDI79967; EAH_00047830.
DR   GeneID; 25272853; -.
DR   OMA; MFLQPEA; -.
DR   Proteomes; UP000018050; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000220; C:vacuolar proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   InterPro; IPR026028; V-type_ATPase_116kDa_su_euka.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom.
DR   PANTHER; PTHR11629; PTHR11629; 2.
DR   Pfam; PF01496; V_ATPase_I; 2.
DR   PIRSF; PIRSF001293; ATP6V0A1; 3.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000018050};
KW   Hydrogen ion transport {ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018050};
KW   Transmembrane {ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    588    621       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    633    656       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    715    733       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    745    764       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    931    952       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   COILED       48     75       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   992 AA;  107528 MW;  39891620956B99ED CRC64;
     MGLFRSEPMR LGTLVLPQEG ARDFIVAIGT AVKVQIEDMN GMSLSRGYRR QLQRLEELER
     ILRYLKEKIE DISGVRLVHV AQDLDRAADA AAAAAAASVY NAAAAADHAD VEAAGGGAAA
     AASAAAAAAA AEKPQVYVLD RVEDMLNKVY RQFLRFAQNN QDLQREKIAA EEELAVVSFA
     ASQLRSSLRS PWRLDPGSAA AAAAAAAAAA AEDPKIAATS TCSSSNTLQQ QQQQQQTNTP
     SAATADAHAR SSSARRRRPT QLSSSNSGSS SSSSWQADVQ QQEKQQTFPY SASRRLLSAG
     GLGGLESGEM SSLVFSSVAG IVAAKDQERF ARAMFRSTRG NAFTHFKRLE EEELTAYPHG
     EEPKSLFVTY FQGAATGSAF MEKVKCVCSA MGARTYNWPH SGAEAQQRQQ QLQQLLRDKA
     AAAAAYEQYF LNEVGVFLEA VPASNLPLIP AAASAAAAAA AAEGDLTAAA AAAAAAAAGV
     RRRPLITELQ RFVERERAVY TTLNLFALSD ATLQADCWFL EAEEAALRKT LAQVAAEKST
     SAFLLVHASE GLGLRSPPTS FSRCSFMSSF QGLVDTYGVA RYGEANPALF AAAIFPFLFG
     LMFGDVGHGL LLLLLAAALL WCRSRGYVFT DELLCMLVEA RYLILLMALH SIYAGFMYND
     VFSMGINLFG SRWGPSKEGG PPEPVAGGPY PFGVDPAWKG ASNELLFLNS LKMKLAIIVG
     FVHMLLGLAL FILNTIHFKD WRSLLLTAVL RLVLLLCLPV MFLGKPLLEL YVHRRRQPPP
     GFQSLNSVDS SAIQLQQLHQ QQQQQQYHQP YHHHHQQQRQ QQQQYVALAT MGSRGEKDSR
     AAAPSAAAAA VAAAGSGVAA AEEEMDVTEL WLHNMIEGIE FVLGSISNTA SYLRLWALSL
     AHQQLSCIFF EKTVGLAFQP GLSPSQMAFK LIFFFPAFLC ITIFVMVAME ALECFLHALR
     LQWVEFQNKF YKGDGVPFRP LDLNCLPGDS TS
//
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