ID U6H174_9EIME Unreviewed; 7677 AA.
AC U6H174;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=HECT-domain (Ubiquitin-transferase) containing protein, putative {ECO:0000313|EMBL:CDI85592.1};
GN ORFNames=EPH_0059130 {ECO:0000313|EMBL:CDI85592.1};
OS Eimeria praecox.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Eimeriidae; Eimeria.
OX NCBI_TaxID=51316 {ECO:0000313|EMBL:CDI85592.1};
RN [1] {ECO:0000313|EMBL:CDI85592.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Houghton {ECO:0000313|EMBL:CDI85592.1};
RA Reid A.J., Blake D., Billington K., Browne H., Dunn M., Hung S.,
RA Kawahara F., Miranda-Saavedra D., Mourier T., Nagra H., Otto T.D.,
RA Rawlings N., Sanchez A., Sanders M., Subramaniam C., Tay Y., Dear P.,
RA Doerig C., Gruber A., Parkinson J., Shirley M., Wan K.L., Berriman M.,
RA Tomley F., Pain A.;
RT "Genomic analysis of the causative agents of coccidiosis in chickens.";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CDI85592.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Houghton {ECO:0000313|EMBL:CDI85592.1};
RA Aslett M.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; HG694022; CDI85592.1; -; Genomic_DNA.
DR EnsemblProtists; CDI85592; CDI85592; EPH_0059130.
DR VEuPathDB; ToxoDB:EPH_0059130; -.
DR OrthoDB; 226847at2759; -.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 3.30.2160.10; Hect, E3 ligase catalytic domain; 1.
DR Gene3D; 3.30.2410.10; Hect, E3 ligase catalytic domain; 1.
DR Gene3D; 3.90.1750.10; Hect, E3 ligase catalytic domains; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR000569; HECT_dom.
DR InterPro; IPR035983; Hect_E3_ubiquitin_ligase.
DR PANTHER; PTHR13491; ZCCHC10 PROTEIN; 1.
DR PANTHER; PTHR13491:SF0; ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 10; 1.
DR Pfam; PF00632; HECT; 2.
DR SMART; SM00248; ANK; 3.
DR SMART; SM00119; HECTc; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF56204; Hect, E3 ligase catalytic domain; 1.
DR PROSITE; PS50237; HECT; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Transferase {ECO:0000313|EMBL:CDI85592.1};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786,
KW ECO:0000256|PROSITE-ProRule:PRU00104}.
FT DOMAIN 7421..7663
FT /note="HECT"
FT /evidence="ECO:0000259|PROSITE:PS50237"
FT REGION 71..132
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 230..265
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 583..607
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 639..663
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 738..772
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 821..857
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 930..952
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 980..1005
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1157..1187
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1221..1242
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1323..1364
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1570..1597
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1643..1682
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1880..1920
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1950..1989
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2212..2234
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2652..2717
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2781..2820
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3298..3325
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3732..3787
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4167..4247
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4254..4273
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4432..4464
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4607..4630
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4678..4720
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4866..4891
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4927..4946
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5046..5071
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5267..5286
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5330..5355
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5670..5704
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5748..5846
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 6052..6155
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 6212..6241
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 6492..6631
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 6729..6764
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 7245..7329
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 7383..7408
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 163..201
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1262..1306
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2823..2850
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 74..91
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 100..126
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 230..259
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 742..772
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 931..952
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 982..1002
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1646..1682
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1887..1920
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1950..1986
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2212..2231
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2659..2716
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2799..2820
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3308..3325
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4434..4464
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5049..5068
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5330..5354
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5748..5770
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5787..5801
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 6056..6107
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 6128..6155
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 6557..6571
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 6578..6631
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7268..7306
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7387..7401
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 7631
FT /note="Glycyl thioester intermediate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00104"
SQ SEQUENCE 7677 AA; 802486 MW; F2EC1129D2076514 CRC64;
MGAREGDTEE PAAAAAAAAA ATAADTVHPC LSSGLQQQQQ QQQQQQQQLC AHAAAAAAAA
AAAEGRLSLS SVVSGAPAAI SSSSSSGVSA GERVASRGAA AAAQQQQQQQ QQRQQQQQQQ
AVGPLERNST EPAADSLGEI YPLHNPAAAA WAPHDSSNPG LTLQQQQQQQ QQQQQQQQQQ
QHVLQQQQQQ QQQLLQQQQQ QHLLHQQQQQ LLQQQQQQRR SYWLAAAFPN CSSSSSSSGN
SSSSSSSRSS NSSSRSPAAA APAAATPAAA APASAPPAAT ASGGGGASES SAAAAAAATA
AAATAAAAAT AAAATEEAVE DPIVLSIEWL SPQPLLINAS AAARHSRNIC LPAANVSEGA
ALASEAAAAA ATGAAAAAAA AAAAAAGPVL EESLAASVGS VGPLALNSGL PRALHPLQLQ
LQTLVTAAAA SWGSRFAAAA SSSSSSSSSR TPRRGLRSRY MQAAEGLRPY RCLGALWSEE
QRQQQQQQQQ VQQQQQQTAL EREGELLLVG PLQLLQQQDT QTSFGIWLAT QKGERYPQLL
LQLLHAAKSR LLAGLPAAFV GPRRRAAAAA AAAGAAAAAA AGAPAAAAEE EEEGEEEQKG
DAQDPLEAKS CCRGTAAQRE MGALLRLLLQ AAQQQARRGL EKQREGDSWG YPSAETLQQQ
QQQQQQQQQQ QQQQQQQEGD SQQQAWEAVA LALDCLLLLA LHKGRLCCLL QFILILMETA
DSLSCCQVSP AAPPAAAALL PSPSTHDNSS SSSSSSNSSS NSSSSSSKGQ QPVHVRRYLW
EPKYAFPSLD ALELLTLQRR CWFAAAAATT AAAAADSPRQ YVIEGGYGGP PSGREEGGAP
RGKGGGPPGS EDEPTLRLLS NGLGGPGATI TQLQLLLPQP ADLEFVGDSS EAAAAAAAAE
TPGAAAGVEG AACVLLEFLY GNERLIRLRR EGSSSSSSNS NSNSSSSSSS ISEDGESLIL
YIEVSSSALA VWMRGGEENM FKTEEEGEEE ETAAEEETTE EEETVEKPRV LLYDLQGERM
LTLELLLDRG GYQVDAVEAA AAAAAATTTG TAAASTTTTA AAAAGGGAAA AANDSHLLKL
LQQPQEGLVL FINGEKICSL RLSSLSSTPA SLQLQPKQLL LTAELMGGAV LLSPPSPSFS
PAFVEELRAR AILSNSPKPR YSISSSSSSN SRSSSNSSSS SSNSNGSSTT TKFSLEQFLQ
LTCEAVHRLC LKGAEELLQS SSSSSSSSSS SSSSSAARQT HSNFAASDPL SGVQHIVASG
DAAAVEAALQ LLEYQKKRWQ QQQQQQQQQQ QQQQQQQRQR QKQQEAVGAS NSDSVLCCIS
SSSSASSSDR PVSEEQTAAC NSSSSNSSSS SSSRSSGPQE EVGSSVTAVA ATTAGAAAAA
AAAGAAAGAC EWLRYREEIL QQQQQWQMRA ECMYSVLCVL RLLLSPQHPA SKGGALQGLG
CMSSRLMDML LFYFYKEAPA CNICCCSACI QQQGGGAMEI VGALFDAQGA AWLLSRGSTL
LLSTATPTNL QLLLQGARPH TLQQLLLALS SKRQQQESSL AYVLLLLDVL EGQKAGQIIV
SRLLHETRGP PLRLMGAPGG PQGPPGGTAD RRGGAPPSTQ LLQRFAAAVE QQQLRGGALG
EEGGPSGLRL VGAAAVAAAA AASSMWGDTS RPSARRPSPL SFEALQQQQQ QQQQQRQKQQ
QQQQQSVLHD ACTRLASQHY SGFWPLLFCL LEATETQMKE DLRGLQQSAS AAAPASCCSR
LRCCSSKGAA AAAAAAAAAA AASADTSGPQ DAFSSKTWSA CSSSKYPSNC SRCPRCCSRG
PWRGPCGAPP RQLHTSPGFT VGALCHPRLV GLPTGTAAGR DMCACGELLQ RPSLWIPLQH
RLQQLQQVLR RGGGELWGDG AAAAAAGTSG DSSSNRTSSN SSNSNSSRSS SSKSSSSRSS
DVAGRVAAQL TRHAAELWLQ QLFRCLQQRS AKGPNSSSSS SSSNEKQRRN SSSSSSSSSS
NRRWSDAAEV TEGLPSPVWV GGPSLHSLSV DSPSAAAAAA AAAVKGTGGP QQRQAYSGGP
PTLSFGGRLL PWEQTGQASA AAAAAAACQY LEKLFGASLR TANNLLSLML DTVASGGPTV
AALLVCGPRG AYPSSSSSAA AAAAAGAAGG GPSAAAAAAE EKEEEEEGCL QSGDADNCAA
CTLQAQQLLQ PIGAPEPALL HGSSFLGGGV LPLLSFLTPL LQLLMAIIRG SKSSSSSSSN
SSSSSSRGNR SRSRKSSIRC VDAATADTIA AVLGFVLRLW PSLLLLSLRC LLLLRQLNTC
MSEDPCQGSL HPLGEQLLGI VSAAASVLQQ ISSSSFPRLL ASIDLSYTAA AAAAAEGQTE
EEISKAAAAL PPLLLRGAQY VAAAASHPLK PLEQALRSSL LLLLDYTARV SVQQQQQLGF
IALPAAVEDF LAATQQTPAS SCCDQQQQQQ QQQQQQQKQQ QQQQPEEPSQ LLLLHASQPM
QQPTGGLLLH CRGLSAAARG ASRQQQTPQQ QLLEASFAAA ERAAATPSNS DCFSFSATHR
LDPSEVSAAA AAAAAAQTTA TAAAAATAAG GGGGLGSKRH CCPSLLRLLQ GDCEDRNLSS
RFAGFHPRVA AVQRAIFAAV LHLLGYEDSA ENGREGTAEE QQEALLCLAA SVSRRAGMQL
LATWQRRRAE KATAAKETAA ETDCSSSTPL ALSDSDEFGQ GDPMSSSSWP ASPIQAEQQQ
QQQQQQQQQQ MLPPSRTNEA RDIIARCWWL LSYCPPGLAV PEGRQLHAKR SVRHLLSSSS
SSSSSTGGEA SGAVLIRSVS SPSIGGGQGH GWGLGLGGGG RQQQQQVLQQ QALQKQQQQP
MPQQQQQQQQ QQQQQQKQQQ QQQQQQQQQH HKEARFRLSA CREGLLSSRL PRYSEARQEE
TVAVSSLHHF IESPLEGDRL RGFLASSSCA RSVQMLKRFL RSGRRRSKRS ASQPWGASAR
AAAAAAAATG ATAAAAAAAA AAARGGASTA KETSGHAGAA PAAAAAAAAA AAAAAAVRRS
RRNPHHAWGN LALRSAAAGP RRLQLGRHRS GRAAAAAAAA AAAAAEGRSS SEGTTESNLQ
AFVEFILKGG DVYTVQRVLL VEQLASLIRY VSLNSLRALL ISGLGVVEAP PVSCLLDGDP
VGPHSSSHEG LLPYAAAAAA AAGHRLLPEV STEEVLGLGV TSSGSWGTRE GLLGALIEAP
GVLLQSQQQQ QQQQQQQQQQ QQQQQVVVRS SRRFDTAPSF ACARRALMSG VNAPSAPPYG
RGGLGCVEAV FSFEGPLQGR VIESDCSDSS CCREISCTTA SSEAACVLQQ LDGGIQQGLK
VEPPSKTGEP HRSSSSSSNS SSSNSHSSSC MQPFWKSQPL AEALDASLGE AVRTVFRLHV
QQHVRDMLCL ASSASRGVLS LLPADCCWME AELQLLTLHL CLGRDPFGSS SSSVLLLQHL
LTLALPVPLR LLHSAADARP RGLSLETVPS RDLHEDAAAA AATAATAAGR GSSYYYPRGS
SVDMFAAGAT ATAPTAAAAS TRPAAAAAAA AQPAAPAAAV APAAAAGGER ESSVDMFAAG
ATATAPTAAA ASTRPATAAA AAAAQPAATA AAVAPAAAAG GGERESFAFK RFASSFSSLD
CLSSTPSPRA VYLSLSAALT GPTAGEANGR EESIAEVRLQ LQLQQQQQQQ QQQQQQQREG
EVSWGVGRVG AASLGMGTPW GDSSHCRPSS SSLRREGFAL EVSVQLSDNL WAHVWASKGL
LVYEAPPTSG EAAGAAAAAR DDPRSPPPAR LDRSSSSGCA QREEGGDGGA PKLPSTTPGG
PGGPGGLGFL GLLRSEDFAS SSFLPSSWAL SWGIEEKMRL LLRREYEGAK LRLQQSAWRA
FQAALWFVLA GSEEETEEGD RWFLAAAVQQ EDKLPKKALL EGPPPNPSNC LQRSMQRAAV
AVEALKLCLH VVQRLADLQT QTLRDLRRSN SLGLRGGADI MPVCSRSSTG LGRYEGDKDK
EQETAEALLI GEAVFVSRAT SESSSSLADR GSLGVEEEGF ITSSMGGLPE KLLFTERLID
RTLILLLRCV RASSSAAMLL LKTLLINFRT IPIQLEAVLR TLPVKARLYE LLTECVRRLA
PPPALEASSS SAAATTTTTT AAAAAGVGCS TGAWAALGAP SVMGVGGGQR LFSRESSDGS
SRLLPPLQPV SLGSLLHAAG PLLQLHQEST DFGGGPPSQG RPVPGSEGQE LVFGNAAEGE
GASGPREEGL QAPQTVGGPW MPTGGNTGVT GGVAGPTGLQ EQPSSSSLAE LGAPLVSNSA
GGGEGETGSD SGDFAALPQS EVFLCSVPSE EFQAEVHGRT LHVLRARELG RFGVTVAPAD
CVLSAAQDIF ERNDVVGFRT STCPPFWGDV FATTVSYQPG DYLSVKFSVD EQPNGQRCLH
TELHVSGESI GSVLEVFYDQ HTQVEQRRRM NLVFVLQDPL TLVYGGPDFT LQYTDPDSHP
NNNNNNGQTA LLAGGTVGGG ASQQQTGALG LLSSSSNPPS QQTLRSLRLH PLVIQSLRLY
QAVLRASDTP LLLRGERQGA LQQLSQVLEQ CTTALGSVFE GLCSNSTNTH QELPRQGDSS
QRLFARGDSL QLPLNRRGLL DRLAASRRDS SGELQLQLQL QLQGEELKGR EGAAATAEPR
RQTSTGLRPC ACPQQQRSAR VKQEMLQTCR RGVAALGVLC CDCLGRGELQ DVLDRAERQR
PPGTIDPDGI HPSAATGSGR GAASGAPGAP PDSAEAAAGE EGGGLGLPWL VSTSCLQLSA
VAGLRLNECE ALVVAVSQLL TSPVIQGTLH QIAAVGRVVA PSSDWAELQA LALTLGSKAI
VALCLLLRSM LQQTHEGDIS LSPRTQKCLL KVFIFIEQFC FLTSGLATHQ IDPFTVEEAS
DIYPSACNSS ETSPHIPLQP HHPRSSRSAS VPDLRLPAAA ATAAAAAPAP TPTAVAAAAA
AAVGGGSPAA AGGAPATSPQ DAYVGAGETS WPPGQRGFGG CVGEGEGADG EAKLKLEKIA
RLCGVPEIVF ETEGLESLAV SGEAVLAAGE TAKVWSWVYR LNEGWNEALD AAVAAAFQTA
AAGPLAAMTE ESERDRGDKG DISASGRKRQ QLRRVQQLIG RGWDSPAASL LLPKPRQEGG
FIHFRGPVDV RVFNYEGACS LWSSRMLHRL LEPPLRWALR RDALHLVSPT NSPSTRGALR
RITPAPDPAA EAAAAEAAAA EAAEPAATTT AAAEAWKPAH TIQCRSVAAA TTAVEPFVRA
VQTLPVSVFI AEPVSSTRAV GNLEAFPGSF LLLNLQPLHE TQRRKQQWGG LLQRPAETEG
ETAAGGEFIG REVKELRKTP RLLVALDRNL EHLVGESSNC SQTPEWMPAM TATRSSSSSN
SSNSSSSGGE SDAGNDELQV SLMWSRCKDL SGPEGESKGG GVVSRLEVSN LHGVWKNGGV
TVYACSSLPL QCGASSASCS VCFAVHASGG EGSLDMHGLE EGLPLSRVFF GAVDSRQREQ
LLAGSWDGLT DAALLQLSSR ELKCGFDPPL PGRQWGSPQG HRGVKRGGLA ALLGTQRAER
AAPEALRSIV GPPGLKIMLR AVGRHLLWLS QEQLLAAQLL PPGCTAVVPV LLLGERPAAC
TAPAVSSLWR RLLFSATLGP SDVHRPVVVP FNEVFYALEP APADSPARLL GPPGGSIGRS
ESLTAAAAAA ASSGASAAGP SAAAAAVLGD PKGLGEREKE DPAAASRHTA ASAGGGVAVA
GAEGSGTTQR WQVLSLSPKI RGGVSLRLPV GAPAAYSSAV WRWVQRPEVT RESTEEGVSD
SPREEEAEAA RAAAASAAGS MDTWAVGPFS ETRQPSLSGG LGDSLQPGAG EGPPLQLGGG
GGPPPTGPSA AATRAVLSSS PLPGRGPPCM LNLRQQQGGL SIQNSDVAVL SSSPLPGRGP
PCMLNLRQQQ GGLSIQNSDA QESARGSAPL LDVGSVYPAL PFRVQFKGIP TANGAAAGTQ
MVGIVWGLCR WLWFSNGRLL CPLDLPLGEL MRLHAVGAHL NLRGAPRGAP KTSAEGWKDT
HVTLGVAGYS TRDLVEIEFQ PAIPALLFKK NDVYQFGFSF ERFYQWAPPR VARQPQQQPV
HMQPQQQQQQ QQQQQQQQQQ LLMQQHHQPH QLQHDQQQQQ HQPVLQVPAS SAAKEREAML
FPPQRFRSTE LVSASSGSVG PRTLGTGGPP SSTRHLDVHQ GTVYALFQAI KDRNVRWLLG
FFAQFPNWLE AHDAAAAPGS CTFGSLEQQL ATWSGNGGGG SSSSNSSNSS GSSSGNSSHW
QGEQLQQHIT ALYGEHAHDT PLKLAIQRGY ADVAQVLIEE GGCNPEGFGG SSDRCTPLML
AADLGQELLV ASLVCTYGVW VDRRDAEGNS ALHRAALRAA EPTVNSGRPN AAAPVYRRGC
YNIIKLLLSL GADASLKNDA GLTPLDLIGT RGGAATGGAP QERIEAVAAL LRHAAVTGQM
QQSGLVAAAV YSNSNSWKAA PEAVKATGTS ASAPWVWGSL LANCTVVVGG AGVVALGLHA
LYIDGERRDA QATEGDRLTS SPRGGPETAQ AAGGLQGALP QASGRVAAPA APRCGQPRSE
EPQLQTGGIR LSALKGPVPP SSSSSAGEKM QESTEGGIAT RVGRSSTTSL VSSNSAVVSP
SQRGSGVSSA TAGDSHSSCC PAHPSSSNSS TGAVFPSLLR PLEGRLPVVG VDTRTLLQQL
LVWGLELNGG VSASPRVEGQ SSPLRAPLAA LSPSLLGGLA LSEGFQDVQT VFVAITRRLL
LLEEQAAADR MQPPPQSPVA VAASPQPGPR AVPAGPRRPD GLRHRGTREE PFLTVAAALS
PSSSGLQRLA ASAEAAESSE DLCSLLLPLD SIACSIEGGT RRGWAESMQR RLWRQRVARD
LGYQVAVGGP GGLVWTPDVQ LLEEVSAGLG HEAARQVLPE GMNGGGWGLL VVRSLINRDA
FILQTVSNRW PLKLDIWLRQ LLDLFDGPEE GRAVPQPDKH LRIAALIWQA DRDRDALLLS
LNNNNNASSP LGGKTNALEE LERAAALKEE VLTLIKGALE EVSSDTPLEV LLQQVVGLRL
RLLEHLCACG SRAVPSVAPV FNIPKLPLNY YGLLTAESGS AFFRGLVVGR GSKGGRPFGE
PLSSSKMVLQ VGPSDLPIEM SAYLFLRPLL TNVMVSSLWR SIVEKLGFSS REQPSLRLDR
GQAATAKHLQ HTLWCQATMQ LLSAAANPCR LRARAGDRPF LVVFRGEGAT DFGGPFQEFL
SGVANEVMGA VAETPEAFLS SFIPCLPCLN STHAIGPHQD SVVLRPDARS PLPDPLVSAA
DLRPPPTLEE SDSSNGVSGS RLGSARGSTE RFQEAAGQQA ETTSCLHSAW PPGEGAASPR
SPRVSGLRDR RLRRNLQAET LWTSDTILSA LPSPARRVLP RGHDPNGVGL PYRDALVDPF
SAETARREEV QGSSTAASRT ASPPRAEEEA AADEDLYILM YEALGRLMAM CFCIGSAFNV
TLNPLLWKKL VAAPLSIEDV ADSDCVAVEM LRSLRRLAAV PPQFWDATME ASLSDMTFSA
EDTLGRSCEL VEGGADVPVN AFNLATFIRL SERFRLLEGQ EGIEAVLRGI AAVLPLGRLR
LLFDWRRLEY RVCGDREVDV ATLKEHTECS FVCGRSRLPV ASSDWRMTVD YETIDRGAAI
NDNRLPTAAT CSFRLVMPPY SSVAVMRERL LYAINNCTAI DLDAVVVHEQ MQLMYDD
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