ID U6JXS7_9EIME Unreviewed; 572 AA.
AC U6JXS7;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Sulfate adenylyltransferas-adenylylsulfate kinase, putative {ECO:0000313|EMBL:CDJ30234.1};
GN ORFNames=EMH_0005890 {ECO:0000313|EMBL:CDJ30234.1};
OS Eimeria mitis.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Eimeriidae; Eimeria.
OX NCBI_TaxID=44415 {ECO:0000313|EMBL:CDJ30234.1};
RN [1] {ECO:0000313|EMBL:CDJ30234.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Houghton {ECO:0000313|EMBL:CDJ30234.1};
RA Reid A.J., Blake D., Billington K., Browne H., Dunn M., Hung S.,
RA Kawahara F., Miranda-Saavedra D., Mourier T., Nagra H., Otto T.D.,
RA Rawlings N., Sanchez A., Sanders M., Subramaniam C., Tay Y., Dear P.,
RA Doerig C., Gruber A., Parkinson J., Shirley M., Wan K.L., Berriman M.,
RA Tomley F., Pain A.;
RT "Genomic analysis of the causative agents of coccidiosis in chickens.";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CDJ30234.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Houghton {ECO:0000313|EMBL:CDJ30234.1};
RA Aslett M.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; HG682384; CDJ30234.1; -; Genomic_DNA.
DR RefSeq; XP_013352801.1; XM_013497347.1.
DR AlphaFoldDB; U6JXS7; -.
DR EnsemblProtists; CDJ30234; CDJ30234; EMH_0005890.
DR GeneID; 25375609; -.
DR VEuPathDB; ToxoDB:EMH_0005890; -.
DR OrthoDB; 22780at2759; -.
DR GO; GO:0004020; F:adenylylsulfate kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004781; F:sulfate adenylyltransferase (ATP) activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0000103; P:sulfate assimilation; IEA:InterPro.
DR CDD; cd02027; APSK; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.10.400.10; Sulfate adenylyltransferase; 1.
DR InterPro; IPR002891; APS_kinase.
DR InterPro; IPR025980; ATP-Sase_PUA-like_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR024951; Sulfurylase_cat_dom.
DR NCBIfam; TIGR00455; apsK; 1.
DR PANTHER; PTHR42700; SULFATE ADENYLYLTRANSFERASE; 1.
DR PANTHER; PTHR42700:SF1; SULFATE ADENYLYLTRANSFERASE; 1.
DR Pfam; PF01583; APS_kinase; 1.
DR Pfam; PF01747; ATP-sulfurylase; 2.
DR Pfam; PF14306; PUA_2; 1.
DR SUPFAM; SSF52374; Nucleotidylyl transferase; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF88697; PUA domain-like; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000313|EMBL:CDJ30234.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 13..65
FT /note="ATP-sulfurylase PUA-like"
FT /evidence="ECO:0000259|Pfam:PF14306"
FT DOMAIN 75..161
FT /note="Sulphate adenylyltransferase catalytic"
FT /evidence="ECO:0000259|Pfam:PF01747"
FT DOMAIN 243..384
FT /note="Sulphate adenylyltransferase catalytic"
FT /evidence="ECO:0000259|Pfam:PF01747"
FT REGION 173..240
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 173..196
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 206..232
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 572 AA; 64978 MW; A81BAFD18FFA15D1 CRC64;
MKDVLIGVLY HPVIAQLDVE SVYLPDLEEE MQKVLGTTDP NHPYVKYLRD NHSECYYVGG
KITPVNPIVH FNFEHYRMSP ALCKQRIRDR NYDVVVGFQT RNPLHRSHYE LIKHALKTAA
ATEKKRPMLL LSPVVGPTQP GDVPYYLRTR CYEHVIRHFE QDGECKFSHL CPTTTSTPNR
SPPRTQQQQQ THSTESTRQD GECKFSHLCP TTTSTPNRSP PRTQQQQQTH STESTRMEED
CSSNAMLVLI PLAMRMAGPR ECVLHARIRK NYGCTHFIVG RDHAGPSTRK QDGTPFYGPY
DAHKLLGSVA DKLGITPIFG EEMLYVGEEF GGYIPAGRLE DVKKQNPNVE VNSISGTEFR
KRLTTRMPIP EWFSFPSVIV ELQQFYKQNH ERGLCVYFTG LPCSGKSTLA NALEAAILEN
RNERRKITLL DADVVRQHLS KGLGTNVRRI GYIASEITKH GGICIVANIA PYTCDREFNR
KLIEQEGGVY VEVYVCTPLS VCEERDIKHL YKKARQGIIK QFTGVSDPYE APQHPELTID
SSSDIKDKVC QVHQYLKDQG YVLEAPPLNK CC
//
