ID U6KR12_EIMTE Unreviewed; 890 AA.
AC U6KR12;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Exosome complex exonuclease, putative {ECO:0000313|EMBL:CDJ37848.1};
GN ORFNames=ETH_00025180 {ECO:0000313|EMBL:CDJ37848.1};
OS Eimeria tenella (Coccidian parasite).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Eimeriidae; Eimeria.
OX NCBI_TaxID=5802 {ECO:0000313|EMBL:CDJ37848.1};
RN [1] {ECO:0000313|EMBL:CDJ37848.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Houghton {ECO:0000313|EMBL:CDJ37848.1};
RA Reid A.J., Blake D., Billington K., Browne H., Dunn M., Hung S.,
RA Kawahara F., Miranda-Saavedra D., Mourier T., Nagra H., Otto T.D.,
RA Rawlings N., Sanchez A., Sanders M., Subramaniam C., Tay Y., Dear P.,
RA Doerig C., Gruber A., Parkinson J., Shirley M., Wan K.L., Berriman M.,
RA Tomley F., Pain A.;
RT "Genomic analysis of the causative agents of coccidiosis in chickens.";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CDJ37848.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Houghton {ECO:0000313|EMBL:CDJ37848.1};
RA Aslett M.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; HG673784; CDJ37848.1; -; Genomic_DNA.
DR RefSeq; XP_013228686.1; XM_013373232.1.
DR AlphaFoldDB; U6KR12; -.
DR EnsemblProtists; CDJ37848; CDJ37848; ETH_00025180.
DR GeneID; 25254146; -.
DR VEuPathDB; ToxoDB:ETH2_0300400; -.
DR VEuPathDB; ToxoDB:ETH2_0300500; -.
DR VEuPathDB; ToxoDB:ETH_00025180; -.
DR OrthoDB; 5472588at2759; -.
DR GO; GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR CDD; cd05789; S1_Rrp4; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR025721; Exosome_cplx_N_dom.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR048565; RRP4_S1.
DR PANTHER; PTHR10019:SF13; PB1 DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR10019; SNF5; 1.
DR Pfam; PF14382; ECR1_N; 1.
DR Pfam; PF21266; RRP4_S1; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF110324; Ribosomal L27 protein-like; 1.
PE 4: Predicted;
KW Exonuclease {ECO:0000313|EMBL:CDJ37848.1};
KW Hydrolase {ECO:0000313|EMBL:CDJ37848.1};
KW Nuclease {ECO:0000313|EMBL:CDJ37848.1};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 20..56
FT /note="Exosome complex component N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14382"
FT DOMAIN 69..139
FT /note="RRP4 S1"
FT /evidence="ECO:0000259|Pfam:PF21266"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 178..213
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 258..284
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 339..362
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 182..213
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 890 AA; 95299 MW; 4FC52C8861E5AABF CRC64;
MWVDQQQQQQ RSSSSSSSKI VLPGEPLHLG EGFLLGLNTH VEDGVARSSV CGVLQTVNRL
VYVKPLKSRY EANVGDVVVG RVADIANGKW LVDVGAARLA VLTLGGVSLD VQRRRDESDL
LDMRVLFKPS DLLCCEVQKT LLIKRQSRHI ASLKCGLQLI LGVNGYLWIS VPSVGSEEAG
AAQPPAQQQQ QQQQQQQQQQ QHHSAQQPPP GCNSFSSCSS SCSSFGSSSN SSRYSSSSSS
STPFGSLLVP LEETLQPLQQ QQQQQQQQQQ QQQQALRTSK SRLSRSLLQQ QQQQLLRERI
EAARSATELL RLVQQQHKNL DAASAAAAVI RFAKIQQHQQ QQTFPSSSSR NSSSRSSSRR
AMSTETLLKH STFYRLLLLL QLQLSLGAPL PLAALVYIPW AFGRLLLHCS SHKELAADML
RQIESRLLLH LPSQQQQQQR QQQQQQQQQP LPLQQLRCSG LCLLVWGLSK AGASQTLWQF
AAAAIRDKLH LFNPHEVASL LYSFARTKDP RALEAAAATP TAAAATATAA AAAAAEPSAP
AAAAAAAEPT ATVAAAAAAV PSAPTAAAAA AAEPTATAAA AAAAEPSAPA APAASAARAA
AATAADLAAA AAPVAAPDGS EAAAAEAAAA AEEIDAAAGA AAATAAAATC EPQSLLSLLA
ERAAAAAAAM KGRTLSTAAL ALTNLTSSSS SSSNSSSSSS GRDIASSKSA FLAAAASQII
PKAHTFDTQA LTLLLYSYSL EYQQQQQQRQ QQQQQVTVAV LESLAAALQQ QQQLLLPEGL
CICCLVLSRC KWKDSWRLFS VLENQLLKLQ SFECFSLQLL KLQSFECFSL QQLIVLLWSA
AKLKQQQLQQ QQPQQQQQPQ QQQQQQQQQQ QQQQQNVELL RRLTEELSSR
//
