ID U6LF61_9EIME Unreviewed; 1856 AA.
AC U6LF61;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=ABC1 family beta-lactamase, putative {ECO:0000313|EMBL:CDJ47204.1};
GN ORFNames=EBH_0015080 {ECO:0000313|EMBL:CDJ47204.1};
OS Eimeria brunetti.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Eimeriidae; Eimeria.
OX NCBI_TaxID=51314 {ECO:0000313|EMBL:CDJ47204.1};
RN [1] {ECO:0000313|EMBL:CDJ47204.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Houghton {ECO:0000313|EMBL:CDJ47204.1};
RA Reid A.J., Blake D., Billington K., Browne H., Dunn M., Hung S.,
RA Kawahara F., Miranda-Saavedra D., Mourier T., Nagra H., Otto T.D.,
RA Rawlings N., Sanchez A., Sanders M., Subramaniam C., Tay Y., Dear P.,
RA Doerig C., Gruber A., Parkinson J., Shirley M., Wan K.L., Berriman M.,
RA Tomley F., Pain A.;
RT "Genomic analysis of the causative agents of coccidiosis in chickens.";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CDJ47204.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Houghton {ECO:0000313|EMBL:CDJ47204.1};
RA Aslett M.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; HG710646; CDJ47204.1; -; Genomic_DNA.
DR EnsemblProtists; CDJ47204; CDJ47204; EBH_0015080.
DR VEuPathDB; ToxoDB:EBH_0015080; -.
DR OrthoDB; 995984at2759; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd05121; ABC1_ADCK3-like; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 2.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR004147; ABC1_dom.
DR InterPro; IPR001466; Beta-lactam-related.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR43173; ABC1 FAMILY PROTEIN; 1.
DR PANTHER; PTHR43173:SF3; ABC1 FAMILY PROTEIN; 1.
DR Pfam; PF03109; ABC1; 1.
DR Pfam; PF00144; Beta-lactamase; 2.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 2.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1379..1405
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1417..1434
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1446..1463
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1470..1490
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1510..1529
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1568..1588
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1637..1657
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1700..1720
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1732..1752
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1758..1780
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1792..1814
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1820..1841
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 106..352
FT /note="ABC1 atypical kinase-like"
FT /evidence="ECO:0000259|Pfam:PF03109"
FT DOMAIN 494..573
FT /note="Beta-lactamase-related"
FT /evidence="ECO:0000259|Pfam:PF00144"
FT DOMAIN 576..659
FT /note="Beta-lactamase-related"
FT /evidence="ECO:0000259|Pfam:PF00144"
FT REGION 641..793
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 805..899
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1009..1060
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 641..664
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 678..714
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 754..784
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 807..827
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 829..847
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 873..898
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1014..1030
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1031..1054
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1856 AA; 202090 MW; AE094D8283CF5889 CRC64;
MESALFYAQT AATQPVFRLA RPKQTAAFHT LWCWSNVYVG WKVAQARSRA LPQDKQAAYW
EQRHEHFANL VWDNIKELKG WWVKVGQFLS TRSDLLPQQY IHHLIKLQDM MPTTPYAVIE
KTLQTELGDL NEIFSKIEEK PLASASIGQV HRAWLKDGTA VVVKVQHADV ESLLMHDMAN
LKQLSWAFGL LEQGMNFAPI LEEWQKAASK ELDFRFEYAH QTRAYEAAQR SGIGVVIPKC
YPNLVTKSVM VMEFIDGFKV TDVEKLDQYG IDRRELMYKL CDSFAYQIHI DGLFNGDPHP
GNILVCIDPV TKEAKPVILD WGLVKEFDSK GQTAFSKLVY SVASMDVMGL MEAFEHMGFM
FKEGKGAVVD PEIYMEALRV AFREGEVEKN ETEALHKAAG ETVQAAVKAG VTRKKIQEAN
PLEDWPKDII FFVRVASLLH GLCVQLKVHI PFLQIMVRRA QECLFNRYQP PSPLIYTHFL
GGRGAAKCSL HQRLNRLLKG LVERKLVLGC QVAVCFEGEM IIDAAIGQMG PVDTRPVTPD
SLFCGYCTAK GLLSTALLQL VSSGELELDD AVSSCEMVRI VEDAAPASPP GAWGRYAYLT
YGWAVSELVR CVSGMSIDAF VQERLLEPLG LKSEIFIRVP QETEQSSSPA ERPQQTSAGA
AKDSKTSSPP MKPAAAPSSA RQRSTDSMRM VSSSQHAVHV SSTLELQHSS LSKGRGPSPL
AERLAAAGFS GNNKPVPSSG RSKTLDSLRS SHDADTATHA SSSVNGGSQQ QQQGNRSGSL
LLPGSQTPRR DDYGDAVHDA EAWARGSTEN HLSSNTSSRS PHLVSTPKTD ELSPERESSR
DRSVLSPSLE HKVAPSEPSS QRNIEADDGP SERSRCNSSS SSKCSAPVPG SSQGAEKGQL
SAFPKEVEIV TADTPLLWRL TSARRKISFN PMTQQEVLQR LKETQGKLEG ENEQGDGVQS
SFQTRRHIAS AMRRRRRCLM NVKGNSGPLE HMREAQICNT RSAESLPDVF SRTRAVRQAE
DDRQKSEEEG GLSQSDVVTE GLRTPDSDSD SQGVASPAPG AAPRVSVLEL IRTKPHVMDP
LIYDSHRIVH QLIPPSNCRC TARALARFYA ALGEGQIISK PLLDAARVAH TVDPTLEALL
LTGGGSRTWG LGYQLYDCAY LSPPGWGGAR PGQGTHTGAS FLHSRFSSVG DFITRRIRRS
RDTGIFGCGG SSSSAVQHPD VEALLRDRGL SSSHPWGATL GLKPRGVVGL GHGDVGGSVA
VCFPEMNLSI SILLNDVLTG PEASQIILEF VLKCFGLQPK WQTQVSINEV LENLTPPPTQ
SHPRRRLARP TIRESVISAS KGHAQRIPSD VYDENDMNDT TAPVGAHKCR AQMALVGAFL
IHLTLGSLHA FGNIAPLIIA YMRLLQPTAS LRYHDGLILY VSAVLVQGIA GFFGGRLHRA
LGPSKATLLG GSVMSIGLVM SALTLHSCFL FCLSFGVVTA IGSGLCYPVP LTCALEWQPD
KKGTVSCVIF LGRSLSVCLL CPMHSLFLFR ATQPSLLAFV SPLGGADGAA TAPEVYVSDT
EVLHRLPALF LLMAGGCLVL QAVGAALLSD PPPLPMDSHE RRKLIEEIRS PSPSTAASLL
SSFVLTPQDL CSSPSFWLLF MMLFFSWQSV LVAAYMWKIV PFAFIHKVSP STYMDPAEHS
LLPATSFTEG ISNWQSVTDL QLSTIGAVAG ALCVAGRLVW GYIGNKAGNK RAIIIMNLCM
AALLVTFMNS SMTSPRNFGV WLALLNACHG GLFSLLPSLT SDLFGHKNFG PVFSLLFAAR
LCAAACICIL TKVVLELTDG VTLCMTLAGC HVLCAGLALA FHPTEALPNP YKLVMT
//
