ID U6MY78_9EIME Unreviewed; 1351 AA.
AC U6MY78;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=DNA ligase, putative {ECO:0000313|EMBL:CDJ69192.1};
GN ORFNames=ENH_00064670 {ECO:0000313|EMBL:CDJ69192.1};
OS Eimeria necatrix.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Eimeriidae; Eimeria.
OX NCBI_TaxID=51315 {ECO:0000313|EMBL:CDJ69192.1};
RN [1] {ECO:0000313|EMBL:CDJ69192.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Houghton {ECO:0000313|EMBL:CDJ69192.1};
RA Reid A.J., Blake D., Billington K., Browne H., Dunn M., Hung S.,
RA Kawahara F., Miranda-Saavedra D., Mourier T., Nagra H., Otto T.D.,
RA Rawlings N., Sanchez A., Sanders M., Subramaniam C., Tay Y., Dear P.,
RA Doerig C., Gruber A., Parkinson J., Shirley M., Wan K.L., Berriman M.,
RA Tomley F., Pain A.;
RT "Genomic analysis of the causative agents of coccidiosis in chickens.";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CDJ69192.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Houghton {ECO:0000313|EMBL:CDJ69192.1};
RA Aslett M.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; HG725679; CDJ69192.1; -; Genomic_DNA.
DR RefSeq; XP_013437659.1; XM_013582205.1.
DR GeneID; 25476604; -.
DR VEuPathDB; ToxoDB:ENH_00064670; -.
DR OrthoDB; 209192at2759; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:InterPro.
DR GO; GO:0051103; P:DNA ligation involved in DNA repair; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 1.10.3260.10; DNA ligase, ATP-dependent, N-terminal domain; 1.
DR Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR InterPro; IPR021536; DNA_ligase_IV_dom.
DR InterPro; IPR036599; DNA_ligase_N_sf.
DR InterPro; IPR029710; LIG4.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR PANTHER; PTHR45997; DNA LIGASE 4; 1.
DR PANTHER; PTHR45997:SF1; DNA LIGASE 4; 1.
DR Pfam; PF01068; DNA_ligase_A_M; 1.
DR Pfam; PF11411; DNA_ligase_IV; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR PROSITE; PS50172; BRCT; 1.
PE 4: Predicted;
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:CDJ69192.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 165..190
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 197..227
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 821..911
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 552..607
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 684..708
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 974..1022
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1259..1294
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 552..571
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 578..607
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 687..708
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 975..999
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1279..1294
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1351 AA; 140008 MW; 2A5F8BDC7DB600A0 CRC64;
MALSPSLITN ADSLPFSEVC AAVRKLGDPL ASNADKTEFA LGLLSRFSAE CDLFPFLRLL
LPHRDRRRPF LGLRLGAVLG VYAEAFALPA AAVSLLQQYK DPAAAAAIHA HALLNRLSDL
KASQGWKIWR DFSSDAKPGE QQQQQQQQQQ QQQQQQQQQQ QQQEFLLLVL LLVLLLVLWL
VFLLLLLLLL SLLLLLLLLL LLLLLLLLLL LVLLLLLPLL LLLLLLLQQQ QQIGAMGTDY
TQRYGYTSRH RHQQQQQQQQ QQQQLQQQQQ QQQQQPPEDL CVLLLQQFRG HSCILDGEIF
AADSSSKKPL PFKSIKRVAA AETAQQFLVY VVFDILSYSS SDGVEVYRQP LLNMRLEDRK
LEKCCSKSAA KAAKDLSSKS RFPSIDSTRG KLPPAAAAAA AAAAAAAAAA AAAAAGTAAA
AAAAAAAAAD CAAGGDPDCV DDGDGMQKVT REMLQKEQQQ QQQQQQQQQQ PQPQQQQCQQ
HQQHQVDVTW PVHVSWVVSL IAAEFIVSNE FDIPFTFRFP RLLEAPRRDK TPREATTLQQ
LLQLQQQQQQ KQQQQQLPGF SSGNDSLSPR GDDSPQDLLE EPQQQQQQQQ QQQQQQLRAQ
DTSSFNTSGT VETAACLEDF EEPQDPLLAA FSKAMTQQQQ QQQQQQQQQC EKQQLQQIGL
AAEAGNLGSA EAPRQTAAAP EAPMLIDPQD SSSSSSSSCS SSSSSSCSST DCSNTLQSTA
FPLSPYPYAK RQRRNAATAL LSPTAAAAPA AAAKAAAAAA AAAKRSRAGV IKGSPHRLVS
HLLPARVAPP SGSAAAAAAA AAAPEAGAAA AAAAAAAAAA GRDLPLRGLQ LWVLEGDLKH
PKEALERVAL SLGAAVLQSP RGSLFAAVAA AASFRTAAAA AAFPQVPVLR LEWLLACQQQ
QQQVPLLPRF LLHAPQQLQQ QLAQDYDQYG DSYYDSTTPE ELRHCLQAAA AAAAAAAAAA
AAPAAAAAEG SSASGAARSP VSDLQKQQQQ QQQQQSGAAA AAAAAAKEHC SSPAARGTPS
RTWRAVTAAA AALAAAEAAR TPTRRVLHTA GGAAAAAAAA AAAAGTPCSE PSTGLNREAA
AATPAAATRA AATPAAATPA AATPAAATPA AAAATAAGSE GKDDIKDTLE LLLAAAAEID
ESAATLFSLY NTNYYFEDKQ AAAATAATAA AAAAAPAPAG AAAAAAAAAA AEDTDLTSDT
SCQALGEWPA AAAAAAAAAA AAAAPVLRRR ATKALYTFLG GCPALSPAAA THIVTSGAPV
SGPAAGGPPG APKEGPLGGP NSSKQQQQST AETAAAPVLS WEAVEEKVHA VQAAAATAAA
AVAAAAAAFT PNTSSSAAAA AAPAAALGTL P
//
