ID U6N4E6_9EIME Unreviewed; 646 AA.
AC U6N4E6;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=GDA1/CD39 (Nucleoside phosphatase) family domain containing protein, putative {ECO:0000313|EMBL:CDJ68815.1};
GN ORFNames=ENH_00065440 {ECO:0000313|EMBL:CDJ68815.1};
OS Eimeria necatrix.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Eimeriidae; Eimeria.
OX NCBI_TaxID=51315 {ECO:0000313|EMBL:CDJ68815.1};
RN [1] {ECO:0000313|EMBL:CDJ68815.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Houghton {ECO:0000313|EMBL:CDJ68815.1};
RA Reid A.J., Blake D., Billington K., Browne H., Dunn M., Hung S.,
RA Kawahara F., Miranda-Saavedra D., Mourier T., Nagra H., Otto T.D.,
RA Rawlings N., Sanchez A., Sanders M., Subramaniam C., Tay Y., Dear P.,
RA Doerig C., Gruber A., Parkinson J., Shirley M., Wan K.L., Berriman M.,
RA Tomley F., Pain A.;
RT "Genomic analysis of the causative agents of coccidiosis in chickens.";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CDJ68815.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Houghton {ECO:0000313|EMBL:CDJ68815.1};
RA Aslett M.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the GDA1/CD39 NTPase family.
CC {ECO:0000256|ARBA:ARBA00009283}.
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DR EMBL; HG725606; CDJ68815.1; -; Genomic_DNA.
DR RefSeq; XP_013437282.1; XM_013581828.1.
DR AlphaFoldDB; U6N4E6; -.
DR GeneID; 25476681; -.
DR VEuPathDB; ToxoDB:ENH_00065440; -.
DR OrthoDB; 261519at2759; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR Gene3D; 3.30.420.40; -; 1.
DR Gene3D; 3.30.420.150; Exopolyphosphatase. Domain 2; 1.
DR InterPro; IPR000407; GDA1_CD39_NTPase.
DR PANTHER; PTHR11782; ADENOSINE/GUANOSINE DIPHOSPHATASE; 1.
DR PANTHER; PTHR11782:SF3; APYRASE 6-RELATED; 1.
DR Pfam; PF01150; GDA1_CD39; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|PIRSR:PIRSR600407-2};
KW Nucleotide-binding {ECO:0000256|PIRSR:PIRSR600407-2};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..646
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004677403"
FT REGION 92..130
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 238..308
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 339..370
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 428..506
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 535..591
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 100..130
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 339..364
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 453..467
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 535..558
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 571..589
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 212
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR600407-1"
FT BINDING 322..326
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR600407-2"
SQ SEQUENCE 646 AA; 66131 MW; ADCF4E3FE74448D2 CRC64;
MARTWGPLIL FLLFSLLRGP FAPAAAAAAA AAAAAPIRRK AVVIDAGSTG TRVYVYNYTY
TPRGPPRCRW SCQQQQRSEP GVTAFVDNFE DSEEEDLELE KEKEKEKEKE KEKEKEEKKE
VATSGEKFHS DAAESRSLGV YVQQLQQFVF AAVPAAAERA ETFLFFRGTA GLRSLQQQQQ
QLLLHAICSK LNLWGLKFVP GASCGVLTGH EEGALGWLAL NQLLGALEPH LLMVTSSSSS
SSSSSSSSSS SGESSSSSGE GSGSGSESSS SSGESSSSDS SSSSSESSSS SSESSSSSSS
SSGEGAAAAT KRSTAAMVEM GGASAQVVFE LPLSLLPEEQ QQQQQQQQQQ QQQQQVSGVR
TPETEGGSNF LLPVKGHSDL KLLKLQNKYF LLFAKSYLGL GRQLALVRVA ARSLKEHYKS
QALHLELHHK PFPNPNPKTP KPQTLSHTPT PGAPGAPGAP GAPGAPQAPG APEASGAPGA
SGAPGAPEGA PSGAPGAPGA PESGGAPGVY VQLPSAWEYE APLSCFPEDV TFSLDLSSSS
SSSSSSSSSS SSSSYFVMDE FLHSDEGSRG RSSKQQQQQQ QQQQETHTAA AAAAAAAAAA
AAAAAAAAAA ESAAAAAAAA AAAAAAAAAA AAAADVELGV CDSGNG
//
