ID   U6N4M3_9EIME            Unreviewed;       980 AA.
AC   U6N4M3;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=TPR domain-containing protein, putative {ECO:0000313|EMBL:CDJ69655.1};
GN   ORFNames=ENH_00072830 {ECO:0000313|EMBL:CDJ69655.1};
OS   Eimeria necatrix.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC   Eucoccidiorida; Eimeriorina; Eimeriidae; Eimeria.
OX   NCBI_TaxID=51315 {ECO:0000313|EMBL:CDJ69655.1};
RN   [1] {ECO:0000313|EMBL:CDJ69655.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Houghton {ECO:0000313|EMBL:CDJ69655.1};
RA   Reid A.J., Blake D., Billington K., Browne H., Dunn M., Hung S.,
RA   Kawahara F., Miranda-Saavedra D., Mourier T., Nagra H., Otto T.D.,
RA   Rawlings N., Sanchez A., Sanders M., Subramaniam C., Tay Y., Dear P.,
RA   Doerig C., Gruber A., Parkinson J., Shirley M., Wan K.L., Berriman M.,
RA   Tomley F., Pain A.;
RT   "Genomic analysis of the causative agents of coccidiosis in chickens.";
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CDJ69655.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Houghton {ECO:0000313|EMBL:CDJ69655.1};
RA   Aslett M.;
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; HG725765; CDJ69655.1; -; Genomic_DNA.
DR   RefSeq; XP_013438121.1; XM_013582667.1.
DR   AlphaFoldDB; U6N4M3; -.
DR   GeneID; 25477414; -.
DR   VEuPathDB; ToxoDB:ENH_00072830; -.
DR   OrthoDB; 196041at2759; -.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.12710; -; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   InterPro; IPR000683; Gfo/Idh/MocA-like_OxRdtase_N.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR038375; NDUFAF7_sf.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR001440; TPR_1.
DR   InterPro; IPR019734; TPR_repeat.
DR   Pfam; PF01408; GFO_IDH_MocA; 1.
DR   Pfam; PF00515; TPR_1; 1.
DR   SMART; SM00028; TPR; 2.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS50005; TPR; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW   TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW   ProRule:PRU00339}; Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   REPEAT          525..558
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   DOMAIN          576..689
FT                   /note="Gfo/Idh/MocA-like oxidoreductase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01408"
SQ   SEQUENCE   980 AA;  108479 MW;  FA25D5C2BE1F3CD5 CRC64;
     MADKGPPFRG SGIATVGGEA PVEQCPQEKF CVEEDSPLCD SIMWKMLDNY YKQVAIEAWA
     HDYVPSFVTS NSRLCRSYAK IIINFLQDWF RRPEADPTQP VTILEIGGGH GRFTFLLLRA
     LQRYKRLFAS LGLPERPFLV VFSDVAEANV DFCSKHPALK TFVEMQWLDF AIFDGNKDRE
     VHLVVRNEPL TNGAAPVVAI CNYVLDSLLT DSWRITPGAC THEFERSLVS IYSPSEEQQL
     DAPDIMLRMT LGWKWKGVNL DAACDPSNPE KIDYLHKDPT IKEVLLRYRQ LNKQLSFVLP
     IGAFALFRNL SHIGGGRLFC LVGDKGYPTA DEFVGPRDPH IAIHGSISFM LNLHAVRIFF
     ECMGGFSHAT PYRDTFQVTG LWLCGTEHEM GRSVAAFLED VEDLAPDALI NWQRAAQETV
     AAGGGPASSI KSLISLLRYS AHDADVFLNF SNEFTSQCVH PYLNPRTEHD LIGDLEETFA
     NWYKLKKGED VADVCGHICM RLGRCDKALK FLQASADLEP ERTHPSTYVN LASCHKVEGK
     LEAGIKCCEK ALQIDPNYTQ AIQMLRTLNM CINPAKVALI GLGYWTQYEA LPLLRRDTRL
     KIVAAFAFKQ EDVATLVEKA ELQGVELYSG SQGLSSLLER SDIQALVVDV HMQLMMSLLP
     RVFAAGKHLL TRSPLQMSLS SAAALLDIYK PYCNSVVWHA VENNRQEEAF VEAAAKLATL
     GRVTSVSFRC GTDTALKYKF STAPYDIKHH MALDLLRCVT ALRQITGLQM SSLSAVAKGD
     HAPCCGSPSS QLEDKPDKIK NTRLRREYAR LSGWLTFVNP SSHQSVLGSF VISHCVGDNS
     LTYKINCLRG TMKLTKASSC WRIDITGEKV PGGTSFAVQS IGHQNCHDAF AEELYEKLRS
     TEKSTGGANS EEGPTLVDIS INGALADSAI IEGILASMQN DGAPARFGSP VSEAVEGHKK
     MDKKSASLRS VHCYDSTTVA
//