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Database: UniProt
Entry: U6NZU8_HAECO
LinkDB: U6NZU8_HAECO
Original site: U6NZU8_HAECO 
ID   U6NZU8_HAECO            Unreviewed;       559 AA.
AC   U6NZU8;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   22-NOV-2017, entry version 12.
DE   SubName: Full=PUA and Translation initiation factor SUI1 domain containing protein {ECO:0000313|EMBL:CDJ85497.1};
GN   ORFNames=HCOI_00637300 {ECO:0000313|EMBL:CDJ85497.1};
OS   Haemonchus contortus (Barber pole worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Strongylida; Trichostrongyloidea; Haemonchidae; Haemonchinae;
OC   Haemonchus.
OX   NCBI_TaxID=6289 {ECO:0000313|EMBL:CDJ85497.1, ECO:0000313|Proteomes:UP000025227};
RN   [1] {ECO:0000313|Proteomes:UP000025227}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISE/inbred ISE {ECO:0000313|Proteomes:UP000025227};
RX   PubMed=23985316; DOI=10.1186/gb-2013-14-8-r88;
RA   Laing R., Kikuchi T., Martinelli A., Tsai I.J., Beech R.N., Redman E.,
RA   Holroyd N., Bartley D.J., Beasley H., Britton C., Curran D.,
RA   Devaney E., Gilabert A., Hunt M., Jackson F., Johnston S.L.,
RA   Kryukov I., Li K., Morrison A.A., Reid A.J., Sargison N.,
RA   Saunders G.I., Wasmuth J.D., Wolstenholme A., Berriman M.,
RA   Gilleard J.S., Cotton J.A.;
RT   "The genome and transcriptome of Haemonchus contortus, a key model
RT   parasite for drug and vaccine discovery.";
RL   Genome Biol. 14:R88.01-R88.16(2013).
RN   [2] {ECO:0000313|Proteomes:UP000025227}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISE/inbred ISE {ECO:0000313|Proteomes:UP000025227};
RA   Huang N.-L., Huang M.-D., Chen T.-L.L., Huang A.H.;
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:CDJ85497.1, ECO:0000313|Proteomes:UP000025227}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISE/inbred ISE {ECO:0000313|EMBL:CDJ85497.1,
RC   ECO:0000313|Proteomes:UP000025227};
RA   Laing R., Kikuchi T., Martinelli A., Tsai I.J., Beech R.N., Redman E.,
RA   Holroyd N., Bartley D.J., Beasley H., Britton C., Curran D.,
RA   Devaney E., Gilabert A., Jackson F., Hunt M., Johnston S., Kryukov I.,
RA   Li K., Morrison A.A., Reid A.J., Sargison N., Saunders G.,
RA   Wasmuth J.D., Wolstenholme A., Berriman M., Gilleard J.S.,
RA   Cotton J.A.;
RT   "The genome and transcriptome of Haemonchus contortus: a key model
RT   parasite for drug and vaccine discovery.";
RL   Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; HF962022; CDJ85497.1; -; Genomic_DNA.
DR   Proteomes; UP000025227; Unassembled WGS sequence.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.245.10; -; 1.
DR   Gene3D; 2.30.130.10; -; 1.
DR   Gene3D; 3.30.780.10; -; 1.
DR   InterPro; IPR002478; PUA.
DR   InterPro; IPR015947; PUA-like_sf.
DR   InterPro; IPR036974; PUA_sf.
DR   InterPro; IPR001950; SUI1.
DR   InterPro; IPR036877; SUI1_dom_sf.
DR   InterPro; IPR036885; SWIB_MDM2_dom_sf.
DR   InterPro; IPR004521; Uncharacterised_CHP00451.
DR   Pfam; PF01472; PUA; 1.
DR   Pfam; PF01253; SUI1; 1.
DR   SUPFAM; SSF55159; SSF55159; 1.
DR   SUPFAM; SSF88697; SSF88697; 1.
DR   TIGRFAMs; TIGR00451; unchar_dom_2; 1.
DR   PROSITE; PS50890; PUA; 1.
DR   PROSITE; PS50296; SUI1; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000025227};
KW   Initiation factor {ECO:0000313|EMBL:CDJ85497.1};
KW   Protein biosynthesis {ECO:0000313|EMBL:CDJ85497.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000025227}.
FT   DOMAIN       87    171       PUA. {ECO:0000259|PROSITE:PS50890}.
FT   DOMAIN      467    540       SUI1. {ECO:0000259|PROSITE:PS50296}.
SQ   SEQUENCE   559 AA;  62778 MW;  67CA8B746671D665 CRC64;
     MFRKPFSVKK NNNMRNSDVR KLLQRLPPEV GELIPKKALV AHAKFVTFNG ANLNVYLVDK
     DPMFFDFDAE GVLFPTIYCT KMAPTAFPML LVHEPVLAHL QNGADLMLPG VIRNHDLPIR
     EFARGDVVTI SILTNGQIMG PMAIGVALMS SQEMATSMFM GKGVQPLHIY KDFLWEFGSR
     VVPSILDLQS LLKAEETNEA SVEEGVPSLD ALAVSEQNDS AIPTCTKDET SSPAVVEEEG
     VASDDKDDEP MDQLLYRCFL AALKYRLDQL PIDVGQFYAQ CLLKCVPNGK RLEMKRTKYK
     KFSVFLDEVN KNEDGPLVKI RKEGKGCDVI EEVFKNHPAL RSFVITDEIT KDDEAEQTKS
     GPKIYDYFSI TDAVLPLFKT RGNFSKGQLL DGPQIRELIT DYVKSEELNQ GKHVRLDPIL
     AQVTRISEDI TDWNTLIQKI QNKMTKTFVM RMPDGREIIR KITMPRVVFK VETRSGNKKV
     TLINNLSAFG IEVKKLCHQI QVEAATSATT TNEAVNCEGP QVTVLGNHVT YLGDMLSKEY
     GIDKKYMDGL DLGIKKKKK
//
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