ID   U7KZ76_9CORY            Unreviewed;       867 AA.
AC   U7KZ76;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   27-MAR-2024, entry version 52.
DE   RecName: Full=LTD domain-containing protein {ECO:0000259|PROSITE:PS51841};
GN   ORFNames=HMPREF1281_01983 {ECO:0000313|EMBL:ERS50814.1};
OS   Corynebacterium sp. KPL1855.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC   Corynebacteriaceae; Corynebacterium.
OX   NCBI_TaxID=1203562 {ECO:0000313|EMBL:ERS50814.1, ECO:0000313|Proteomes:UP000017096};
RN   [1] {ECO:0000313|EMBL:ERS50814.1, ECO:0000313|Proteomes:UP000017096}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KPL1855 {ECO:0000313|EMBL:ERS50814.1,
RC   ECO:0000313|Proteomes:UP000017096};
RG   The Broad Institute Genomics Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Jacobson B., Goguen K.,
RA   Pagano E., Lemon K.P., Young S.K., Zeng Q., Gargeya S., Fitzgerald M.,
RA   Abouelleil A., Alvarado L., Berlin A.M., Chapman S.B., Gainer-Dewar J.,
RA   Goldberg J., Gnerre S., Griggs A., Gujja S., Hansen M., Howarth C.,
RA   Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C., Pearson M.,
RA   Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J.,
RA   Nusbaum C., Birren B.;
RT   "The Genome Sequence of Corynebacterium sp. KPL1855.";
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ERS50814.1}.
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DR   EMBL; AXLX01000029; ERS50814.1; -; Genomic_DNA.
DR   AlphaFoldDB; U7KZ76; -.
DR   PATRIC; fig|1203562.3.peg.1913; -.
DR   HOGENOM; CLU_006338_2_0_11; -.
DR   Proteomes; UP000017096; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   CDD; cd10283; MnuA_DNase1-like; 1.
DR   CDD; cd04486; YhcR_OBF_like; 1.
DR   Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR   InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR   InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR   InterPro; IPR047971; ExeM-like.
DR   InterPro; IPR001322; Lamin_tail_dom.
DR   InterPro; IPR036415; Lamin_tail_dom_sf.
DR   NCBIfam; NF033681; ExeM_NucH_DNase; 1.
DR   PANTHER; PTHR42834; ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_3G09210); 1.
DR   PANTHER; PTHR42834:SF1; ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_3G09210); 1.
DR   Pfam; PF03372; Exo_endo_phos; 1.
DR   Pfam; PF00932; LTD; 1.
DR   SUPFAM; SSF56219; DNase I-like; 1.
DR   SUPFAM; SSF74853; Lamin A/C globular tail domain; 1.
DR   PROSITE; PS51841; LTD; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        815..838
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          1..105
FT                   /note="LTD"
FT                   /evidence="ECO:0000259|PROSITE:PS51841"
FT   REGION          109..194
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          329..349
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          634..653
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          779..809
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        111..170
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   867 AA;  91950 MW;  FDE0A44580F93F77 CRC64;
     MAEIRGASFS NDFIELYNPT DAAIDLTGWS VEYFASNGSS GGKITLSGTI APHGYYLVQG
     AAGNGQAQAL PTPDAQGKVN MSGTKGSVQL ADATGNTIDL VGYGAASKSE GAATGSLSND
     TSASRNAAGA DTDDNSADFT IGAPSPTNSG NESPAPQPGG SDNSAGSENL PAPEGITPIA
     EIQGPGDTSP LEGQNVATQG VVTGVWSEGG LNGFTIQTGG TGKEATDASQ ALFVHMGKKG
     ADKYPSIGDS VEVTGQVSEY YGATQVSASS LKQLDTALEE VTPLAVDELL QGDSARESFE
     HMLIQPGTHT VTNNYSLNQY GEVGLAPGDE AFRQPSDVHS PSTDPNSDLQ KLAKDNAEKL
     VTLDDGRTRD YLRTDKDTPL PYIAQDGGKT IKSLRTTDTV EFQHPVIVGY SHDQWRFQPT
     EPVTGETAGT DLPISWEESR DAELHAVDDV KGEYTIGAFN VLNYFTSLGE EFGGSAYTDR
     EGNKVTVNRG KTRGAYTESA LKDQERKIVA AINGLDADVI GLSEIEDGYA VTGDFNQRDK
     ALKRLTEKLN EAAGSEKWAF VPSPSKEQVP EHPDVIRTAF IYHKDVVKPV GESRIFQDPR
     FSGTAREPLA QEFQPLNSDD ESFVAVANHF KSKGSVAKGD EDSGDGQGNN PNVRNAQAQA
     VLDALHKQDD WKDKPLFALG DFNTYTHETA LDVFRNDGFT VPAEKYGADT SYQFGGLLGT
     LDHVLANEVA SGALDDAQVW NINADEPVAF EYSRRNYNAV DFYDDSPFRA SDHDPVKVGF
     TLGEDESTDD GDQGNDANQD DNTDGPGFGF GSSSWGTGAI IGFAILAGLL AIPGFMAATG
     NLQKIIPAGI WGMLPQQAKD FINGLSK
//